Update info.Tools - Reference - Detail
Reference Detail
| Reference | ||
|---|---|---|
| Author | Dixit S., Kumar Biswal A., Min A., Henry A., Oane R.H., Raorane M.L., Longkumer T., Pabuayon I.M., Mutte S.K., Vardarajan A.R., Miro B., Govindan G., Albano-Enriquez B., Pueffeld M., Sreenivasulu N., Slamet-Loedin I., Sundarvelpandian K., Tsai Y.C., Raghuvanshi S., Hsing Y.I., Kumar A., Kohli A. | |
| Title | Action of multiple intra-QTL genes concerted around a co-localized transcription factor underpins a large effect QTL. | |
|
Abstract: Sub-QTLs and multiple intra-QTL genes are hypothesized to underpin large-effect QTLs. Known QTLs over gene families, biosynthetic pathways or certain traits represent functional gene-clusters of genes of the same gene ontology (GO). Gene-clusters containing genes of different GO have not been elaborated, except in silico as coexpressed genes within QTLs. Here we demonstrate the requirement of multiple intra-QTL genes for the full impact of QTL qDTY12.1 on rice yield under drought. Multiple evidences are presented for the need of the transcription factor 'no apical meristem' (OsNAM12.1) and its co-localized target genes of separate GO categories for qDTY12.1 function, raising a regulon-like model of genetic architecture. The molecular underpinnings of qDTY12.1 support its effectiveness in further improving a drought tolerant genotype and for its validity in multiple genotypes/ecosystems/environments. Resolving the combinatorial value of OsNAM12.1 with individual intra-QTL genes notwithstanding, identification and analyses of qDTY12.1has fast-tracked rice improvement towards food security. |
||
| Journal | Sci Rep | |
| Country | the Philippines | |
| Volume | 5 | |
| Pages | 15183 | |
| Year | 2015 | |
| PubMed ID | 26507552 | |
| PubMed Central ID | 4623671 | |
| DOI | 10.1038/srep15183 | |
| URL | - | |
| Relation | ||
| Gene | ABA45 ARF24 AROMA2 CESA10 CRL4 GDA1 GDPD POEI19 SWEET13 WAK125 _ _ | |
| INSD | - | |
| Strain | Wild Core Collection | - |
| Induced Mutation Lines(NIG Collection) | - | |
| Sterile Seed Strain | - | |
|
Lethal Embryo Mutantion Strain |
- | |
|
Stages in Each Organ - Muant Lines (Gene) |
- | |
| Cultivated Varieties(NIG Collection) | - | |
| Stages in Each Organ | - | |
