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Author Mizutani M., Ohta D.
Title Diversification of P450 genes during land plant evolution.
Plant cytochromes P450 (P450s) catalyze a wide variety of monooxygenation/hydroxylation reactions in primary and secondary metabolism. The number of P450 genes in plant genomes is estimated to be up to 1% of total gene annotations of each plant species. This implies that diversification within P450 gene superfamilies has led to the emergence of new metabolic pathways throughout land plant evolution. The conserved P450 families contribute to chemical defense mechanisms under terrestrial conditions and several are involved in hormone biosynthesis and catabolism. Species-specific P450 families are essential for the biosynthetic pathways of species-specialized metabolites. Future genome-wide analyses of P450 gene clusters and coexpression networks should help both in identifying the functions of many orphan P450s and in understanding the evolution of this versatile group of enzymes.
Journal Annu Rev Plant Biol
Country Japan
Volume 61
Pages 291-315
Year 2010
PubMed ID 20192745
PubMed Central ID -
DOI 10.1146/annurev-arplant-042809-112305
Gene CPS4 CYP99A2 CYP99A3 D10 D17 D35 EUI1 GO KS4 MAS PLA1
Strain Wild Core Collection -
Induced Mutation Lines(NIG Collection) -
Sterile Seed Strain -
Lethal Embryo
Mutantion Strain
Stages in Each Organ
- Muant Lines (Gene)
Cultivated Varieties(NIG Collection) -
Stages in Each Organ -