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Author		Mizutani M., Ohta D.
Title		Diversification of P450 genes during land plant evolution.
Abstract: Plant cytochromes P450 (P450s) catalyze a wide variety of monooxygenation/hydroxylation reactions in primary and secondary metabolism. The number of P450 genes in plant genomes is estimated to be up to 1% of total gene annotations of each plant species. This implies that diversification within P450 gene superfamilies has led to the emergence of new metabolic pathways throughout land plant evolution. The conserved P450 families contribute to chemical defense mechanisms under terrestrial conditions and several are involved in hormone biosynthesis and catabolism. Species-specific P450 families are essential for the biosynthetic pathways of species-specialized metabolites. Future genome-wide analyses of P450 gene clusters and coexpression networks should help both in identifying the functions of many orphan P450s and in understanding the evolution of this versatile group of enzymes.
Journal		Annu Rev Plant Biol
Country		Japan
Volume		61
Pages		291-315
Year		2010
PubMed ID		20192745
PubMed Central ID		-
DOI		10.1146/annurev-arplant-042809-112305
URL		-
Relation
Gene		CPS4 CYP99A2 CYP99A3 D10 D17 D35 EUI1 GO KS4 MAS PLA1
INSD		-
Strain	Wild Core Collection	-
	Induced Mutation Lines(NIG Collection)	-
	Sterile Seed Strain	-
	Lethal Embryo Mutantion Strain	-
	Stages in Each Organ - Muant Lines (Gene)	-
	Cultivated Varieties(NIG Collection)	-
Stages in Each Organ		-