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| 文献 | ||
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| 著者 | Huang X., Zhao Y., Wei X., Li C., Wang A., Zhao Q., Li W., Guo Y., Deng L., Zhu C., Fan D., Lu Y., Weng Q., Liu K., Zhou T., Jing Y., Si L., Dong G., Huang T., Lu T., Feng Q., Qian Q., Li J., Han B. | |
| タイトル | Genome-wide association study of flowering time and grain yield traits in a worldwide collection of rice germplasm. | |
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Abstract: A high-density haplotype map recently enabled a genome-wide association study (GWAS) in a population of indica subspecies of Chinese rice landraces. Here we extend this methodology to a larger and more diverse sample of 950 worldwide rice varieties, including the Oryza sativa indica and Oryza sativa japonica subspecies, to perform an additional GWAS. We identified a total of 32 new loci associated with flowering time and with ten grain-related traits, indicating that the larger sample increased the power to detect trait-associated variants using GWAS. To characterize various alleles and complex genetic variation, we developed an analytical framework for haplotype-based de novo assembly of the low-coverage sequencing data in rice. We identified candidate genes for 18 associated loci through detailed annotation. This study shows that the integrated approach of sequence-based GWAS and functional genome annotation has the potential to match complex traits to their causal polymorphisms in rice. |
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| 掲載誌 | Nat. Genet. | |
| Country | China | |
| 刊数 | 44(1) | |
| ページ | 32-9 | |
| 発刊年 | 2012 | |
| PubMed ID | 22138690 | |
| PubMed Central ID | - | |
| DOI | - | |
| URL | - | |
| 関連情報 | ||
| 遺伝子 | ALK ASP1 C LK3 RC WX1 _ _ | |
| INSD | - | |
| 系統 |
野生イネ コアコレクション |
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| 突然変異系統(遺伝研 Collection) | - | |
| 種子不稔系統 | - | |
| 致死変異体系統 | - | |
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組織別発生段階 - 突然変異系統(遺伝子) |
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| 栽培イネ品種(遺伝研 Collection) | - | |
| 組織別発生段階 | - | |
