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Reference Detail
| Reference | ||
|---|---|---|
| Author | Brenda J Reinhart, Earl G Weinstein, Matthew W Rhoades, Bartel B., David P Bartel | |
| Title | MicroRNAs in plants. | |
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Abstract: MicroRNAs (miRNAs) are an extensive class of ~22-nucleotide noncoding RNAs thought to regulate gene expression in metazoans. We find that miRNAs are also present in plants, indicating that this class of noncoding RNA arose early in eukaryotic evolution. In this paper 16 Arabidopsis miRNAs are described, many of which have differential expression patterns in development. Eight are absolutely conserved in the rice genome. The plant miRNA loci potentially encode stem-loop precursors similar to those processed by Dicer (a ribonuclease III) in animals. Mutation of an Arabidopsis Dicer homolog, CARPEL FACTORY, prevents the accumulation of miRNAs, showing that similar mechanisms direct miRNA processing in plants and animals. The previously described roles of CARPEL FACTORY in the development of Arabidopsis embryos, leaves, and floral meristems suggest that the miRNAs could play regulatory roles in the development of plants as well as animals. |
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| Journal | Genes Dev. | |
| Country | USA | |
| Volume | 16(13) | |
| Pages | 1616-26 | |
| Year | 2002 | |
| PubMed ID | 12101121 | |
| PubMed Central ID | 186362 | |
| DOI | 10.1101/gad.1004402 | |
| URL | - | |
| Relation | ||
| Gene | MIR156A MIR160A MIR162A MIR164A MIR166A MIR167A MIR169 MIR171 | |
| INSD | - | |
| Strain | Wild Core Collection | - |
| Induced Mutation Lines(NIG Collection) | - | |
| Sterile Seed Strain | - | |
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Lethal Embryo Mutantion Strain |
- | |
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Stages in Each Organ - Muant Lines (Gene) |
- | |
| Cultivated Varieties(NIG Collection) | - | |
| Stages in Each Organ | - | |
