Tools - Reference - Detail

Reference Detail

Author Chang-Jin Park, Sang-Wook Han, Chen X., Pamela C Ronald
Title Elucidation of Xa21-mediated innate immunity.
In the early 1970s, the Xa21 gene from the wild rice species Oryza longistaminata drew attention of rice breeders because of its broad-spectrum resistance to diverse strains of a serious bacterial disease of rice in Asia and Africa, called 'bacterial blight disease', caused by the Gram-negative bacterium, Xanthomonas oryzae pv. oryzae (Xoo). In 1995, we isolated the gene controlling this resistance and in 2009 demonstrated that Xa21 recognizes a highly conserved peptide, called 'Ax21' (activator of Xa21-mediated immunity). Tyrosine sulfation of Ax21 is required for recognition by rice Xa21. A decade of genetic, molecular and biochemical studies have uncovered key components of the Xa21-mediated signalling cascade. Ax21 recognition by Xa21 at the cell surface induces phosphorylation-mediated events, which are predicted to alter subcellular localization and/or DNA-binding activity of a WRKY family of transcription factors. Because Xa21 is representative of the large number of predicted pattern recognition receptors (PRRs) in rice (n = 328), Arabidopsis (n = 35) and other plant species, further characterization of Xa21-mediated signalling pathways will contribute to elucidation of these important defence responses.
Journal Cell. Microbiol.
Country USA
Volume 12(8)
Pages 1017-25
Year 2010
PubMed ID 20590657
PubMed Central ID 2906629
DOI 10.1111/j.1462-5822.2010.01489.x
Gene WRKY62 XA21 XB15 XB24 XB3
Strain Wild Core Collection -
Induced Mutation Lines(NIG Collection) -
Sterile Seed Strain -
Lethal Embryo
Mutantion Strain
Stages in Each Organ
- Muant Lines (Gene)
Cultivated Varieties(NIG Collection) -
Stages in Each Organ -