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| 文献 | ||
|---|---|---|
| 著者 | Chen X., Chern M., Patrick E Canlas, Ruan D., Jiang C., Pamela C Ronald | |
| タイトル | An ATPase promotes autophosphorylation of the pattern recognition receptor XA21 and inhibits XA21-mediated immunity. | |
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Abstract: Cell-surface pattern recognition receptors (PRRs) are key components of the innate immune response in animals and plants. These receptors typically carry or associate with non-RD kinases to control early events of innate immunity signaling. Despite their importance, the mode of regulation of PRRs is largely unknown. Here we show that the rice PRR, XA21, interacts with XA21 binding protein 24 (XB24), a previously undescribed ATPase. XB24 promotes autophosphorylation of XA21 through its ATPase activity. Rice lines silenced for XB24 display enhanced XA21-mediated immunity, whereas rice lines overexpressing XB24 are compromised for immunity. XB24 ATPase enzyme activity is required for XB24 function. XA21 is degraded in the presence of the pathogen-associated molecular pattern Ax21 when XB24 is overexpressed. These results demonstrate a function for this large class of broadly conserved ATPases in PRR-mediated immunity. |
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| 掲載誌 | Proc. Natl. Acad. Sci. U.S.A. | |
| Country | USA | |
| 刊数 | 107(17) | |
| ページ | 8029-34 | |
| 発刊年 | 2010 | |
| PubMed ID | 20385831 | |
| PubMed Central ID | 2867851 | |
| DOI | 10.1073/pnas.0912311107 | |
| URL | - | |
| 関連情報 | ||
| 遺伝子 | XA21 XB24 | |
| INSD | - | |
| 系統 |
野生イネ コアコレクション |
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| 突然変異系統(遺伝研 Collection) | - | |
| 種子不稔系統 | - | |
| 致死変異体系統 | - | |
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組織別発生段階 - 突然変異系統(遺伝子) |
- | |
| 栽培イネ品種(遺伝研 Collection) | - | |
| 組織別発生段階 | - | |
