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著者		Alder A., Jamil M., Marzorati M., Bruno M., Vermathen M., Bigler P., Ghisla S., Bouwmeester H., Beyer P., Al-Babili S.
タイトル		The path from beta-carotene to carlactone, a strigolactone-like plant hormone.
Abstract: Strigolactones, phytohormones with diverse signaling activities, have a common structure consisting of two lactones connected by an enol-ether bridge. Strigolactones derive from carotenoids via a pathway involving the carotenoid cleavage dioxygenases 7 and 8 (CCD7 and CCD8) and the iron-binding protein D27. We show that D27 is a β-carotene isomerase that converts all-trans-β-carotene into 9-cis-β-carotene, which is cleaved by CCD7 into a 9-cis-configured aldehyde. CCD8 incorporates three oxygens into 9-cis-β-apo-10'-carotenal and performs molecular rearrangement, linking carotenoids with strigolactones and producing carlactone, a compound with strigolactone-like biological activities. Knowledge of the structure of carlactone will be crucial for understanding the biology of strigolactones and may have applications in combating parasitic weeds.
掲載誌		Science
Country		Germany
刊数		335(6074)
ページ		1348-51
発刊年		2012
PubMed ID		22422982
PubMed Central ID		-
DOI		-
URL		-
関連情報
遺伝子		D10 D27
INSD		-
系統	野生イネコアコレクション	-
	突然変異系統(遺伝研 Collection)	-
	種子不稔系統	-
	致死変異体系統	-
	組織別発生段階 - 突然変異系統(遺伝子)	-
	栽培イネ品種(遺伝研 Collection)	-
組織別発生段階		-