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Reference Detail
| Reference | ||
|---|---|---|
| Author | Lee S., Kim Y.S., Jeon U.S., Kim Y.K., Schjoerring J.K., An G. | |
| Title | Activation of Rice nicotianamine synthase 2 (OsNAS2) enhances iron availability for biofortification. | |
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Abstract: Because micronutrients in human diets ultimately come from plant sources, malnutrition of essential minerals is a significant public health concern. By increasing the expression of nicotianamine synthase (NAS), we fortified the level of bioavailable iron in rice seeds. Activation of iron deficiency-inducible OsNAS2 resulted in a rise in Fe content (3.0-fold) in mature seeds. Its ectopic expression also increased that content. Enhanced expression led to higher tolerance of Fe deficiency and better growth under elevated pH. Mice fed with OsNAS2-D1 seeds recovered more rapidly from anemia, indicating that bioavailable Fe contents were improved by this increase in OsNAS2 expression. |
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| Journal | Mol. Cells | |
| Country | USA | |
| Volume | 33(3) | |
| Pages | 269-75 | |
| Year | 2012 | |
| PubMed ID | 22228185 | |
| PubMed Central ID | - | |
| DOI | - | |
| URL | - | |
| Relation | ||
| Gene | IRT1 IRT2 NAS2 YSL15 YSL2 | |
| INSD | - | |
| Strain | Wild Core Collection | - |
| Induced Mutation Lines(NIG Collection) | - | |
| Sterile Seed Strain | - | |
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Lethal Embryo Mutantion Strain |
- | |
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Stages in Each Organ - Muant Lines (Gene) |
- | |
| Cultivated Varieties(NIG Collection) | - | |
| Stages in Each Organ | - | |
