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Reference Detail
| Reference | ||
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| Author | Takanashi H., Ishimaru Y., Bashir K., Fujimoto M., Shimo H., An G., Nagasaka S., Nishizawa N.K., Nakanishi H., Tsutsumi N. | |
| Title | The rice mitochondrial iron transporter is essential for plant growth | |
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Abstract: In plants, iron (Fe) is essential for mitochondrial electron transport, heme, and Fe-Sulphur (Fe-S) cluster synthesis; however, plant mitochondrial Fe transporters have not been identified. Here we show, identify and characterize the rice mitochondrial Fe transporter (MIT). Based on a transfer DNA library screen, we identified a rice line showing symptoms of Fe deficiency while accumulating high shoot levels of Fe. Homozygous knockout of MIT in this line resulted in a lethal phenotype. MIT localized to the mitochondria and complemented the growth of 繝幄姦rs3繝幄姦rs4 yeast defective in mitochondrial Fe transport. The growth of MIT-knockdown (mit-2) plants was also significantly impaired despite abundant Fe accumulation. Further, the decrease in the activity of the mitochondrial and cytosolic Fe-S enzyme, aconitase, indicated that Fe-S cluster synthesis is affected in mit-2 plants. These results indicate that MIT is a mitochondrial Fe transporter essential for rice growth and development. 諱ｯ 2011 Macmillan Publishers Limited. All rights reserved. |
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| Journal | Nature Communications | |
| Country | Japan | |
| Volume | 2 | |
| Pages | 322 | |
| Year | 2011 | |
| PubMed ID | 21610725 | |
| PubMed Central ID | - | |
| DOI | - | |
| URL | - | |
| Relation | ||
| Gene | FPN1 FRO2 IRT1 IRT2 MIT NRAMP1 VIT1 YSL15 YSL2 | |
| INSD | - | |
| Strain | Wild Core Collection | - |
| Induced Mutation Lines(NIG Collection) | - | |
| Sterile Seed Strain | - | |
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Lethal Embryo Mutantion Strain |
- | |
|
Stages in Each Organ - Muant Lines (Gene) |
- | |
| Cultivated Varieties(NIG Collection) | - | |
| Stages in Each Organ | - | |
