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著者 Yilmaz,A., Nishiyama,M.Y. Jr., Fuentes,B.G., Souza,G.M., Janies,D., Gray,J. and Grotewold,E.
タイトル GRASSIUS: a platform for comparative regulatory genomics across the grasses
Abstract:
Transcription factors (TFs) are major players in gene regulatory networks and interactions between TFs and their target genes furnish spatiotemporal patterns of gene expression. Establishing the architecture of regulatory networks requires gathering information on TFs, their targets in the genome, and the corresponding binding sites. We have developed GRASSIUS (Grass Regulatory Information Services) as a knowledge-based Web resource that integrates information on TFs and gene promoters across the grasses. In its initial implementation, GRASSIUS consists of two separate, yet linked, databases. GrassTFDB holds information on TFs from maize (Zea mays), sorghum (Sorghum bicolor), sugarcane (Saccharum spp.), and rice (Oryza sativa). TFs are classified into families and phylogenetic relationships begin to uncover orthologous relationships among the participating species. This database also provides a centralized clearinghouse for TF synonyms in the grasses. GrassTFDB is linked to the grass TFome collection, which provides clones in recombination-based vectors corresponding to full-length open reading frames for a growing number of grass TFs. GrassPROMDB contains promoter and cis-regulatory element information for those grass species and genes for which enough data are available. The integration of GrassTFDB and GrassPROMDB will be accomplished through GrassRegNet as a first step in representing the architecture of grass regulatory networks. GRASSIUS can be accessed from www.grassius.org.
掲載誌 Plant Physiol.
Country USA
刊数 149(1)
ページ 171-180
発刊年 2009
PubMed ID 18987217
PubMed Central ID -
DOI 10.1104/pp.108.128579
URL -
関連情報
遺伝子 2R_MYB2 2R_MYB73 ARID1 BBX6 BHLH083 BHLH1 BHLH148 BHLH31 BHLH44 BHLH59 BHLH60 BHLH98 BRD2 BSRD1 BZIP42 BZIP63 C3H32 DLN17 DLN231 DOF5 DOS DPF DRAP1 E2F1 EHD3 EIL2 ERF33 ERF50 HMGB707 HSFB1 ICE2 LFS LIP19 PLT2 RAI1 RNG1 SAP16 SGSD3 SPL4 TIFY6A WRKY10 WRKY11 WRKY121 WRKY19 WRKY26 WRKY47 WRKY51 WRKY67 WRKY69 WRKY72 WRKY87 ZFP15 ZFP182 _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _
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