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Reference Detail
| Reference | ||
|---|---|---|
| Author | Chen L.-Q., Hou B.-H., Lalonde S., Takanaga H., Hartung M.L., Qu X.-Q., Guo W.-J., Kim J.-G., Underwood W., Chaudhuri B., Chermak D., Antony G., White F.F., Somerville S.C., Mudgett M.B., Frommer W.B. | |
| Title | Sugar transporters for intercellular exchange and nutrition of pathogens. | |
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Abstract: Sugar efflux transporters are essential for the maintenance of animal blood glucose levels, plant nectar production, and plant seed and pollen development. Despite broad biological importance, the identity of sugar efflux transporters has remained elusive. Using optical glucose sensors, we identified a new class of sugar transporters, named SWEETs, and show that at least six out of seventeen Arabidopsis, two out of over twenty rice and two out of seven homologues in Caenorhabditis elegans, and the single copy human protein, mediate glucose transport. Arabidopsis SWEET8 is essential for pollen viability, and the rice homologues SWEET11 and SWEET14 are specifically exploited by bacterial pathogens for virulence by means of direct binding of a bacterial effector to the SWEET promoter. Bacterial symbionts and fungal and bacterial pathogens induce the expression of different SWEET genes, indicating that the sugar efflux function of SWEET transporters is probably targeted by pathogens and symbionts for nutritional gain. The metazoan homologues may be involved in sugar efflux from intestinal, liver, epididymis and mammary cells. |
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| Journal | Nature | |
| Country | USA | |
| Volume | 468(7323) | |
| Pages | 527-532 | |
| Year | 2010 | |
| PubMed ID | 21107422 | |
| PubMed Central ID | - | |
| DOI | 10.1038/nature09606 | |
| URL | - | |
| Relation | ||
| Gene | SWEET12 SWEET13 SWEET15 SWEET16 SWEET1A SWEET1B SWEET2A SWEET2B SWEET3A SWEET3B SWEET4 SWEET5 SWEET6A SWEET6B SWEET7B SWEET7C SWEET7D SWEET7E XA41 | |
| INSD | - | |
| Strain | Wild Core Collection | - |
| Induced Mutation Lines(NIG Collection) | - | |
| Sterile Seed Strain | - | |
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Lethal Embryo Mutantion Strain |
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Stages in Each Organ - Muant Lines (Gene) |
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| Cultivated Varieties(NIG Collection) | - | |
| Stages in Each Organ | - | |
