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Reference Detail
| Reference | ||
|---|---|---|
| Author | Sun Q,Zhou DX | |
| Title | Rice jmjC domain-containing gene JMJ706 encodes H3K9 demethylase required for floral organ development. | |
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Abstract: Histone lysine methylation is an important epigenetic modification with both activating and repressive roles in gene expression. Jumonji C (jmjC) domain-containing proteins have been shown to reverse histone methylation in nonplant model systems. Here, we show that plant Jumonji C proteins have both conserved and specific features compared with mammalian homologues. In particular, the rice JMJD2 family jmjC gene JMJ706 is shown to encode a heterochromatin-enriched protein. The JMJ706 protein specifically reverses di- and trimethylations of lysine 9 of histone H3 (H3K9) in vitro. Loss-of-function mutations of the gene lead to increased di- and trimethylations of H3K9 and affect the spikelet development, including altered floral morphology and organ number. Gene expression and histone modification analysis indicates that JMJ706 regulates a subset of flower development regulatory genes. Taken together, our data suggest that rice JMJ706 encodes a heterochromatin-associated H3K9 demethylase involved in the regulation of flower development in rice. |
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| Journal | Proc. Natl. Acad. Sci. U.S.A. | |
| Country | China | |
| Volume | 105 | |
| Pages | 13679-84 | |
| Year | 2008 | |
| PubMed ID | 18765808 | |
| PubMed Central ID | - | |
| DOI | 10.1073/pnas.0805901105 | |
| URL | - | |
| Relation | ||
| Gene | DH1 JMJ702 JMJ703 JMJ705 JMJ706 JMJ707 JMJ715 JMJ718 JMJ719 MADS24 MADS47 SE14 _ _ _ _ _ _ _ _ _ _ _ | |
| INSD | - | |
| Strain | Wild Core Collection | - |
| Induced Mutation Lines(NIG Collection) | - | |
| Sterile Seed Strain | - | |
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Lethal Embryo Mutantion Strain |
- | |
|
Stages in Each Organ - Muant Lines (Gene) |
- | |
| Cultivated Varieties(NIG Collection) | - | |
| Stages in Each Organ | - | |
