|
Basic Information
|
|
CGSNL Gene Symbol
|
PHR2
|
|
Gene Symbol Synonym
|
OsPHR2, Os-PHR2
|
|
CGSNL Gene Name
|
PHOSPHATE STARVATION RESPONSE 2
|
|
Gene Name Synonym
|
Phosphate Starvation Response2, PHOSPHATE RESPONSE2, PHOSPHATE STARVATION RESPONSE REGULATOR 2
|
|
Protein Name
|
|
|
Allele
|
phr2, Osphr2, osphr2, Osphr2-1
|
|
Chromosome No.
|
7
|
|
Explanation
|
Q6Z156 (japonica). B8B5N8 (indica). PDB: 7E40 (SPX1-PHR2 Complex Structure). PDB accession number 7D3Y (Crystal structure of the osPHR2-osSPX2 complex). PDB accession number 7D3T (Crystal structure of OSPHR2 in complex with DNA). TO:0020102: phosphate content. TO:0006054: arsenic concentration. TO:0020098: nitrate sensitivity. a functional ortholog of AtPHR1. the key transcription factor of phosphate signalling. GO:1900426: positive regulation of defense response to bacterium. GO:0036377: arbuscular mycorrhizal association.
|
|
Trait Class
|
Vegetative organ - Root
Tolerance and resistance - Stress tolerance
Tolerance and resistance - Disease resistance
Vegetative organ - Culm
Reproductive organ - panicle
|
|
Expression
|
|
|
Sequence/Locus
|
|
cDNA Accession No.
|
AK100065
|
|
MSU ID
|
LOC_Os07g25710.1
LOC_Os07g25710.2
LOC_Os07g25710.3
LOC_Os07g25710.4
|
|
RAP ID
|
Os07g0438800
|
|
Links
|
Oryzabase Chromosome View
(
IRGSP 1.0
/
Build5
)
RAP-DB
(
IRGSP 1.0
/
Build5
)
Related IDs List (
IRGSP 1.0
/
Build5
)
|
INSD Accession List
(Test version)
|
-
|
|
Map
|
|
Locate(cM)
|
|
|
Link map
|
Classical linkage map
|
|
References
|
|
He Y., Zhao Y., Hu J., Wang L., Li L., Zhang X., Zhou Z., Chen L., Wang H., Wang J., Hong G.
Mol Plant 2024 17(2) 258-276
The OsBZR1-OsSPX1/2 module fine-tunes the growth-immunity trade-off in adaptation to phosphate availability in rice.
|
|
Liu J., Xu W., Zhang Q., Liao W., Li L., Chen S., Yang J., Wang Z., Xu F.
Plant Commun 2024 5(8) 100930
OsPHR2-mediated recruitment of Pseudomonadaceae enhances rice phosphorus uptake.
|
|
Wang T., Jin Y., Deng L., Li F., Wang Z., Zhu Y., Wu Y., Qu H., Zhang S., Liu Y., Mei H., Luo L., Yan M., Gu M., Xu G.
Plant Cell 2023
The transcription factor MYB110 regulates plant height, lodging resistance, and grain yield in rice.
|
|
Gu P., Tao W., Tao J., Sun H., Hu R., Wang D., Zong G., Xie X., Ruan W., Xu G., Yi K., Zhang Y.
New Phytol. 2023 239(2) 673-686
The D14-SDEL1-SPX4 cascade integrates the strigolactone and phosphate signalling networks in rice.
|
|
Zhang Y., Zhang Q., Guo M., Wang X., Li T., Wu Q., Li L., Yi K., Ruan W.
J Integr Plant Biol 2023
NIGT1 represses plant growth and mitigates phosphate starvation signaling to balance the growth response tradeoff in rice.
|
|
Guo M., Zhang Y., Jia X., Wang X., Zhang Y., Liu J., Yang Q., Ruan W., Yi K.
Plant Cell 2022
Alternative splicing of REGULATOR OF LEAF INCLINATION 1 modulates phosphate starvation signaling and plant growth.
|
|
Guan Z., Zhang Q., Zhang Z., Zuo J., Chen J., Liu R., Savarin J., Broger L., Cheng P., Wang Q., Pei K., Zhang D., Zou T., Yan J., Yin P., Hothorn M., Liu Z.
Nat Commun 2022 13(1) 1581
Mechanistic insights into the regulation of plant phosphate homeostasis by the rice SPX2 - PHR2 complex.
|
|
Xiang D., Meng F., Wang A., Wu Y., Wang Z., Zheng S., Mao C.
Plant J. 2021 107(2) 480-492
Root-secreted peptide OsPEP1 regulates primary root elongation in rice.
|
|
Zhou J., Hu Q., Xiao X., Yao D., Ge S., Ye J., Li H., Cai R., Liu R., Meng F., Wang C., Zhu J.K., Lei M., Xing W.
Nat Commun 2021 12(1) 7040
Mechanism of phosphate sensing and signaling revealed by rice SPX1-PHR2 complex structure.
|
|
Shi J., Zhao B., Zheng S., Zhang X., Wang X., Dong W., Xie Q., Wang G., Xiao Y., Chen F., Yu N., Wang E.
Cell 2021 184(22) 5527-5540.e18
A phosphate starvation response-centered network regulates mycorrhizal symbiosis.
|
|
Sun Y., Song K., Liu L., Sun L., Qin Q., Jiang T., Zhou B., Zhu C., Xu G., Sun S., Xue Y.
J. Exp. Bot. 2021
Silencing of Sulfoquinovosyl Diacylglycerol Synthase 1 Impairs the Glycolipids Accumulation and Photosynthesis in Phosphate-deprived Rice.
|
|
Pandey B.K., Verma L., Prusty A., Singh A.P., Bennett M.J., Tyagi A.K., Giri J., Mehra P.
Planta 2021 254(1) 8
OsJAZ11 regulates phosphate starvation responses in rice.
|
|
Kong Y., Wang G., Chen X., Li L., Zhang X., Chen S., He Y., Hong G.
Plant Cell Environ. 2021
OsPHR2 modulates phosphate starvation-induced OsMYC2 signalling and resistance to Xanthomonas oryzae pv. oryzae.
|
|
Zhang Z., Li Z., Wang W., Jiang Z., Guo L., Wang X., Qian Y., Huang X., Liu Y., Liu X., Qiu Y., Li A., Yan Y., Xie J., Cao S., Kopriva S., Li L., Kong F., Liu B., Wang Y., Hu B., Chu C.
Mol Plant 2021 14(3) 517-529
Modulation of nitrate-induced phosphate response by the MYB transcription factor RLI1/HINGE1 in the nucleus.
|
|
Gho Y.S., Choi H., Moon S., Song M.Y., Park H.E., Kim D.H., Ha S.H., Jung K.H.
Front Plant Sci 2020 11 585561
Phosphate-Starvation-Inducible S-like RNase Genes in Rice Are Involved in Phosphate Source Recycling by RNA Decay.
|
|
He Q., Lu H., Guo H., Wang Y., Zhao P., Li Y., Wang F., Xu J., Mo X., Mao C.
Plant J. 2020
OsbHLH6 interacts with OsSPX4 and regulates the phosphate starvation response in rice.
|
|
Chang M.X., Gu M., Xia Y.W., Dai X.L., Dai C.R., Zhang J., Wang S.C., Qu H.Y., Yamaji N., Feng Ma J., Xu G.H.
Plant Physiol. 2019 179(2) 656-670
OsPHT1;3 Mediates Uptake, Translocation, and Remobilization of Phosphate under Extremely Low Phosphate Regimes.
|
|
Wang W., Hu B., Li A., Chu C.
J. Exp. Bot. 2019
NRT1.1 in plants: functions beyond nitrate transporter.
|
|
Hu B., Jiang Z., Wang W., Qiu Y., Zhang Z., Liu Y., Li A., Gao X., Liu L., Qian Y., Huang X., Yu F., Kang S., Wang Y., Xie J., Cao S., Zhang L., Wang Y., Xie Q., Kopriva S., Chu C.
Nat Plants 2019 5(4) 401-413
Nitrate-NRT1.1B-SPX4 cascade integrates nitrogen and phosphorus signalling networks in plants.
|
|
Ruan W., Guo M., Wang X., Guo Z., Xu Z., Xu L., Zhao H., Sun H., Yan C., Yi K.
Mol Plant 2019 12(8) 1060-1074
Two RING-Finger Ubiquitin E3 Ligases Regulate the Degradation of SPX4, An Internal Phosphate Sensor, for Phosphate Homeostasis and Signaling in Rice.
|
|
Mehra P., Pandey B.K., Verma L., Giri J.
Plant Cell Environ. 2019 42(4) 1167-1179
A novel glycerophosphodiester phosphodiesterase improves phosphate deficiency tolerance in rice.
|
|
Zhong Y., Wang Y., Guo J., Zhu X., Shi J., He Q., Liu Y., Wu Y., Zhang L., Lv Q., Mao C.
New Phytol. 2018 219(1) 135-148
Rice SPX6 negatively regulates the phosphate starvation response through suppression of the transcription factor PHR2.
|
|
Yang J., Xie M.Y., Wang L., Yang Z.L., Tian Z.H., Wang Z.Y., Xu J.M., Liu B.H., Deng L.W., Mao C.Z., Lin H.H.
Plant Cell Physiol. 2018 59(12) 2564-2575
A Phosphate-Starvation Induced RING-Type E3 ligase Maintains Phosphate Homeostasis Partially Through OsSPX2 in Rice.
|
|
Feng H., Li B., Zhi Y., Chen J., Li R., Xia X., Xu G., Fan X.
Plant Cell Rep. 2017 36(8) 1287-1296
Overexpression of the nitrate transporter, OsNRT2.3b, improves rice phosphorus uptake and translocation.
|
|
Mehra P., Pandey B.K., Giri J.
Plant Biotechnol. J. 2017
Improvement in phosphate acquisition and utilization by a secretory purple acid phosphatase (OsPAP21b) in rice.
|
|
Pandey B.K., Mehra P., Verma L., Bhadouria J., Giri J.
Plant Physiol. 2017 174(4) 2316-2332
OsHAD1, a Haloacid Dehalogenase-Like APase, Enhances Phosphate Accumulation.
|
|
Ruan W., Guo M., Wu P., Yi K.
Plant Mol. Biol. 2016
Phosphate starvation induced OsPHR4 mediates Pi-signaling and homeostasis in rice.
|
|
Guo M., Ruan W., Li C., Huang F., Zeng M., Liu Y., Yu Y., Ding X., Wu Y., Wu Z., Mao C., Yi K., Wu P., Mo X.
Plant Physiol. 2015 168(4) 1762-76
Integrative Comparison of the Role of the PHOSPHATE RESPONSE1 Subfamily in Phosphate Signaling and Homeostasis in Rice.
|
|
Ye Y., Yuan J., Chang X., Yang M., Zhang L., Lu K., Lian X.
PLoS ONE 2015 10(5) e0126186
The Phosphate Transporter Gene OsPht1;4 Is Involved in Phosphate Homeostasis in Rice.
|
|
Lv Q., Zhong Y., Wang Y., Wang Z., Zhang L., Shi J., Wu Z., Liu Y., Mao C., Yi K., Wu P.
Plant Cell 2014 26(4) 1586-1597
SPX4 Negatively Regulates Phosphate Signaling and Homeostasis through Its Interaction with PHR2 in Rice.
|
|
Wang Z., Ruan W., Shi J., Zhang L., Xiang D., Yang C., Li C., Wu Z., Liu Y., Yu Y., Shou H., Mo X., Mao C., Wu P.
Proc. Natl. Acad. Sci. U.S.A. 2014 111(41) 14953-8
Rice SPX1 and SPX2 inhibit phosphate starvation responses through interacting with PHR2 in a phosphate-dependent manner.
|
|
Deng M., Hu B., Xu L., Liu Y., Wang F., Zhao H., Wei X., Wang J., Yi K.
Plant Mol. Biol. 2014
OsCYCP1;1, a PHO80 homologous protein, negatively regulates phosphate starvation signaling in the roots of rice (Oryza sativa L.).
|
|
Li S., Wang C., Zhou L., Shou H.
J. Plant Res. 2014 127(3) 433-40
Oxygen deficit alleviates phosphate overaccumulation toxicity in OsPHR2 overexpression plants.
|
|
Shi J., Hu H., Zhang K., Zhang W., Yu Y., Wu Z., WU P.
J. Exp. Bot. 2014 65 859-870
The paralogous SPX3 and SPX5 genes redundantly modulate Pi homeostasis in rice
|
|
Wang S., Zhang S., Sun C., Xu Y., Chen Y., Yu C., Qian Q., Jiang D.A., Qi Y.
New Phytol. 2014 201(1) 91-103
Auxin response factor (OsARF12), a novel regulator for phosphate homeostasis in rice (Oryza sativa).
|
|
Cao Y., Yan Y., Zhang F., Hua-Dun Wang, Gu M., Xue-Neng Wu, Shu-Bin Sun, Guo-Hua Xu
J. Plant Physiol. 2013
Fine characterization of OsPHO2 knockout mutants reveals its key role in Pi utilization in rice.
|
|
Shen C., Wang S., Zhang S., Xu Y., Qian Q., Qi Y., Jiang D.A.
Plant Cell Environ. 2013 36(3) 607-20
osarf16, a transcription factor, is required for auxin and phosphate starvation response in rice (Oryza sativa L.).
|
|
Tian J., Wang C., Zhang Q., He X., Whelan J., Shou H.
J Integr Plant Biol 2012 54(9) 631-9
Overexpression of OsPAP10a, A Root-Associated acid phosphatase, Increased Extracellular Organic Phosphorus Utilization in Rice.
|
|
Sun S., Gu M., Cao Y., Huang X., Zhang X., Ai P., Zhao J., Fan X., Xu G.
Plant Physiol. 2012 159(4) 1571-81
A Constitutive Expressed Phosphate Transporter, OsPht1;1, Modulates Phosphate Uptake and Translocation in Phosphate-Replete Rice.
|
|
Wang C., Huang W., Ying Y., Li S., Secco D., Tyerman S., Whelan J., Shou H.
New Phytol. 2012 196(1) 139-48
Functional characterization of the rice SPX-MFS family reveals a key role of OsSPX-mfs1 in controlling phosphate homeostasis in leaves.
|
|
Chen J., Liu Y., Ni J., Wang Y., Bai Y., Shi J., Gan J., Wu Z., Wu P.
Plant Physiol. 2011 157(1) 269-78
OsPHF1 regulates the plasma membrane localization of low- and high-affinity inorganic phosphate transporters and determines inorganic phosphate uptake and translocation in rice.
|
|
Wu Z. , Ren H. , McGrath S.P. , Wu P. , Zhao F.J.
Plant Physiol. 2011 157(1) 498-508
Investigating the Contribution of the Phosphate Transport Pathway to Arsenic Accumulation in Rice.
|
|
Zhang Q., Wang C., Tian J., Li K., Shou H.
Plant Biol. 2011 13 7-15
Identification of rice purple acid phosphatases related to posphate starvation signalling
|
|
Liu F., Wang Z., Ren H., Shen C., Li Y., Hong-Qing Ling, Wu C., Lian X., WU P.
Plant J. 2010 62(3) 508-17
OsSPX1 suppresses the function of OsPHR2 in the regulation of expression of OsPT2 and phosphate homeostasis in shoots of rice.
|
|
Wu P., Xu J.
Plant Signaling and Behavior 2010 5 712-714
Does OsPHR2, central Pi-signaling regulator, regulate some unknown factors crucial for plant growth?
|
|
Zhou J, Jiao F, Wu Z, Li Y, Wang X, He X, Zhong W, Wu P.
Plant Physiol. 2008 146(4) 1673-86.
OsPHR2 Is Involved in Phosphate-Starvation Signaling and Excessive Phosphate Accumulation in Shoots of Plants.
|
|
DB Reference
|
|
Gramene ID
|
-
|
|
Ontologies
|
|
Gene Ontology
|
symbiosis, encompassing mutualism through parasitism( GO:0044403 )
response to symbiotic fungus( GO:0009610 )
regulation of unidimensional cell growth( GO:0051510 )
regulation of phosphate transport( GO:0010966 )
response to symbiotic bacterium( GO:0009609 )
acid secretion( GO:0046717 )
interspecies interaction between organisms( GO:0044419 )
response to brassinosteroid stimulus( GO:0009741 )
jasmonic acid mediated signaling pathway( GO:0009867 )
defense response to bacterium( GO:0042742 )
inositol phosphate-mediated signaling( GO:0048016 )
phosphate ion homeostasis( GO:0055062 )
transcription factor activity( GO:0003700 )
anion homeostasis( GO:0055081 )
root hair elongation( GO:0048767 )
response to starvation( GO:0042594 )
nucleus( GO:0005634 )
cytoplasm( GO:0005737 )
response to nitrate( GO:0010167 )
phosphorus utilization( GO:0006794 )
nitrogen utilization( GO:0019740 )
phosphate transport( GO:0006817 )
DNA binding( GO:0003677 )
chromatin binding( GO:0003682 )
cellular response to phosphate starvation( GO:0016036 )
|
|
Trait Ontology
|
abiotic stress trait( TO:0000168 )
root hair length( TO:0002665 )
phosphorus sensitivity( TO:0000102 )
bacterial blight disease resistance( TO:0000175 )
brassinosteroid sensitivity( TO:0002677 )
phosphorus uptake( TO:0000511 )
phosphorus content( TO:0001024 )
peduncle length( TO:0002691 )
plant height( TO:0000207 )
relative plant height( TO:0001034 )
internode length( TO:0000145 )
panicle length( TO:0000040 )
total biomass yield( TO:0000457 )
relative total dry weight( TO:0000633 )
relative shoot dry weight( TO:0000636 )
shoot dry weight( TO:0000552 )
relative root dry weight( TO:0000644 )
root dry weight( TO:0000078 )
|
|
Plant Ontology
|
5 root hair formation stage( PO:0007519 )
|
|
Related Strains
|
|
-
|
|
Phenotype images
|
|
-
|
|
Last updated
|
|
Mar 14, 2025
|
Update info.