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Basic Information
CGSNL Gene Symbol PHR2
Gene Symbol Synonym OsPHR2, Os-PHR2
Protein Name
Allele phr2, Osphr2, osphr2
Chromosome No. 7
Explanation Q6Z156 (japonica). B8B5N8 (indica). PDB: 7E40 (SPX1-PHR2 Complex Structure). PDB accession number 7D3Y (Crystal structure of the osPHR2-osSPX2 complex). PDB accession number 7D3T (Crystal structure of OSPHR2 in complex with DNA). TO:0020102: phosphate content. TO:0006054: arsenic concentration. TO:0020098: nitrate sensitivity. a functional ortholog of AtPHR1. the key transcription factor of phosphate signalling. GO:1900426: positive regulation of defense response to bacterium.
Trait Class Tolerance and resistance - Disease resistance
Vegetative organ - Root
Tolerance and resistance - Stress tolerance
cDNA Accession No. AK100065
MSU ID LOC_Os07g25710.1
RAP ID Os07g0438800
Links Oryzabase Chromosome View ( IRGSP 1.0 / Build5 )
RAP-DB ( IRGSP 1.0 / Build5 )
Related IDs List ( IRGSP 1.0 / Build5 )
INSD Accession List
(Test version)
Link map Classical linkage map
Gu P., Tao W., Tao J., Sun H., Hu R., Wang D., Zong G., Xie X., Ruan W., Xu G., Yi K., Zhang Y.
New Phytol. 2023  239(2)  673-686
The D14-SDEL1-SPX4 cascade integrates the strigolactone and phosphate signalling networks in rice.
Zhang Y., Zhang Q., Guo M., Wang X., Li T., Wu Q., Li L., Yi K., Ruan W.
J Integr Plant Biol 2023   
NIGT1 represses plant growth and mitigates phosphate starvation signaling to balance the growth response tradeoff in rice.
Guan Z., Zhang Q., Zhang Z., Zuo J., Chen J., Liu R., Savarin J., Broger L., Cheng P., Wang Q., Pei K., Zhang D., Zou T., Yan J., Yin P., Hothorn M., Liu Z.
Nat Commun 2022  13(1)  1581
Mechanistic insights into the regulation of plant phosphate homeostasis by the rice SPX2 - PHR2 complex.
Pandey B.K., Verma L., Prusty A., Singh A.P., Bennett M.J., Tyagi A.K., Giri J., Mehra P.
Planta 2021  254(1)  8
OsJAZ11 regulates phosphate starvation responses in rice.
Kong Y., Wang G., Chen X., Li L., Zhang X., Chen S., He Y., Hong G.
Plant Cell Environ. 2021   
OsPHR2 modulates phosphate starvation-induced OsMYC2 signalling and resistance to Xanthomonas oryzae pv. oryzae.
Zhang Z., Li Z., Wang W., Jiang Z., Guo L., Wang X., Qian Y., Huang X., Liu Y., Liu X., Qiu Y., Li A., Yan Y., Xie J., Cao S., Kopriva S., Li L., Kong F., Liu B., Wang Y., Hu B., Chu C.
Mol Plant 2021  14(3)  517-529
Modulation of nitrate-induced phosphate response by the MYB transcription factor RLI1/HINGE1 in the nucleus.
Xiang D., Meng F., Wang A., Wu Y., Wang Z., Zheng S., Mao C.
Plant J. 2021  107(2)  480-492
Root-secreted peptide OsPEP1 regulates primary root elongation in rice.
Zhou J., Hu Q., Xiao X., Yao D., Ge S., Ye J., Li H., Cai R., Liu R., Meng F., Wang C., Zhu J.K., Lei M., Xing W.
Nat Commun 2021  12(1)  7040
Mechanism of phosphate sensing and signaling revealed by rice SPX1-PHR2 complex structure.
Sun Y., Song K., Liu L., Sun L., Qin Q., Jiang T., Zhou B., Zhu C., Xu G., Sun S., Xue Y.
J. Exp. Bot. 2021   
Silencing of Sulfoquinovosyl Diacylglycerol Synthase 1 Impairs the Glycolipids Accumulation and Photosynthesis in Phosphate-deprived Rice.
Gho Y.S., Choi H., Moon S., Song M.Y., Park H.E., Kim D.H., Ha S.H., Jung K.H.
Front Plant Sci 2020  11  585561
Phosphate-Starvation-Inducible S-like RNase Genes in Rice Are Involved in Phosphate Source Recycling by RNA Decay.
He Q., Lu H., Guo H., Wang Y., Zhao P., Li Y., Wang F., Xu J., Mo X., Mao C.
Plant J. 2020   
OsbHLH6 interacts with OsSPX4 and regulates the phosphate starvation response in rice.
Mehra P., Pandey B.K., Verma L., Giri J.
Plant Cell Environ. 2019  42(4)  1167-1179
A novel glycerophosphodiester phosphodiesterase improves phosphate deficiency tolerance in rice.
Wang W., Hu B., Li A., Chu C.
J. Exp. Bot. 2019   
NRT1.1 in plants: functions beyond nitrate transporter.
Hu B., Jiang Z., Wang W., Qiu Y., Zhang Z., Liu Y., Li A., Gao X., Liu L., Qian Y., Huang X., Yu F., Kang S., Wang Y., Xie J., Cao S., Zhang L., Wang Y., Xie Q., Kopriva S., Chu C.
Nat Plants 2019  5(4)  401-413
Nitrate-NRT1.1B-SPX4 cascade integrates nitrogen and phosphorus signalling networks in plants.
Ruan W., Guo M., Wang X., Guo Z., Xu Z., Xu L., Zhao H., Sun H., Yan C., Yi K.
Mol Plant 2019  12(8)  1060-1074
Two RING-Finger Ubiquitin E3 Ligases Regulate the Degradation of SPX4, An Internal Phosphate Sensor, for Phosphate Homeostasis and Signaling in Rice.
Chang M.X., Gu M., Xia Y.W., Dai X.L., Dai C.R., Zhang J., Wang S.C., Qu H.Y., Yamaji N., Feng Ma J., Xu G.H.
Plant Physiol. 2019  179(2)  656-670
OsPHT1;3 Mediates Uptake, Translocation, and Remobilization of Phosphate under Extremely Low Phosphate Regimes.
Zhong Y., Wang Y., Guo J., Zhu X., Shi J., He Q., Liu Y., Wu Y., Zhang L., Lv Q., Mao C.
New Phytol. 2018  219(1)  135-148
Rice SPX6 negatively regulates the phosphate starvation response through suppression of the transcription factor PHR2.
Yang J., Xie M.Y., Wang L., Yang Z.L., Tian Z.H., Wang Z.Y., Xu J.M., Liu B.H., Deng L.W., Mao C.Z., Lin H.H.
Plant Cell Physiol. 2018  59(12)  2564-2575
A Phosphate-Starvation Induced RING-Type E3 ligase Maintains Phosphate Homeostasis Partially Through OsSPX2 in Rice.
Mehra P., Pandey B.K., Giri J.
Plant Biotechnol. J. 2017   
Improvement in phosphate acquisition and utilization by a secretory purple acid phosphatase (OsPAP21b) in rice.
Feng H., Li B., Zhi Y., Chen J., Li R., Xia X., Xu G., Fan X.
Plant Cell Rep. 2017  36(8)  1287-1296
Overexpression of the nitrate transporter, OsNRT2.3b, improves rice phosphorus uptake and translocation.
Pandey B.K., Mehra P., Verma L., Bhadouria J., Giri J.
Plant Physiol. 2017  174(4)  2316-2332
OsHAD1, a Haloacid Dehalogenase-Like APase, Enhances Phosphate Accumulation.
Ruan W., Guo M., Wu P., Yi K.
Plant Mol. Biol. 2016   
Phosphate starvation induced OsPHR4 mediates Pi-signaling and homeostasis in rice.
Guo M., Ruan W., Li C., Huang F., Zeng M., Liu Y., Yu Y., Ding X., Wu Y., Wu Z., Mao C., Yi K., Wu P., Mo X.
Plant Physiol. 2015  168(4)  1762-76
Integrative Comparison of the Role of the PHOSPHATE RESPONSE1 Subfamily in Phosphate Signaling and Homeostasis in Rice.
Ye Y., Yuan J., Chang X., Yang M., Zhang L., Lu K., Lian X.
PLoS ONE 2015  10(5)  e0126186
The Phosphate Transporter Gene OsPht1;4 Is Involved in Phosphate Homeostasis in Rice.
Deng M., Hu B., Xu L., Liu Y., Wang F., Zhao H., Wei X., Wang J., Yi K.
Plant Mol. Biol. 2014   
OsCYCP1;1, a PHO80 homologous protein, negatively regulates phosphate starvation signaling in the roots of rice (Oryza sativa L.).
Li S., Wang C., Zhou L., Shou H.
J. Plant Res. 2014  127(3)  433-40
Oxygen deficit alleviates phosphate overaccumulation toxicity in OsPHR2 overexpression plants.
Shi J., Hu H., Zhang K., Zhang W., Yu Y., Wu Z., WU P.
J. Exp. Bot. 2014  65  859-870
The paralogous SPX3 and SPX5 genes redundantly modulate Pi homeostasis in rice
Lv Q., Zhong Y., Wang Y., Wang Z., Zhang L., Shi J., Wu Z., Liu Y., Mao C., Yi K., Wu P.
Plant Cell 2014  26(4)  1586-1597
SPX4 Negatively Regulates Phosphate Signaling and Homeostasis through Its Interaction with PHR2 in Rice.
Wang S., Zhang S., Sun C., Xu Y., Chen Y., Yu C., Qian Q., Jiang D.A., Qi Y.
New Phytol. 2014  201(1)  91-103
Auxin response factor (OsARF12), a novel regulator for phosphate homeostasis in rice (Oryza sativa).
Wang Z., Ruan W., Shi J., Zhang L., Xiang D., Yang C., Li C., Wu Z., Liu Y., Yu Y., Shou H., Mo X., Mao C., Wu P.
Proc. Natl. Acad. Sci. U.S.A. 2014  111(41)  14953-8
Rice SPX1 and SPX2 inhibit phosphate starvation responses through interacting with PHR2 in a phosphate-dependent manner.
Shen C., Wang S., Zhang S., Xu Y., Qian Q., Qi Y., Jiang D.A.
Plant Cell Environ. 2013  36(3)  607-20
osarf16, a transcription factor, is required for auxin and phosphate starvation response in rice (Oryza sativa L.).
Cao Y., Yan Y., Zhang F., Hua-Dun Wang, Gu M., Xue-Neng Wu, Shu-Bin Sun, Guo-Hua Xu
J. Plant Physiol. 2013   
Fine characterization of OsPHO2 knockout mutants reveals its key role in Pi utilization in rice.
Tian J., Wang C., Zhang Q., He X., Whelan J., Shou H.
J Integr Plant Biol 2012  54(9)  631-9
Overexpression of OsPAP10a, A Root-Associated acid phosphatase, Increased Extracellular Organic Phosphorus Utilization in Rice.
Sun S., Gu M., Cao Y., Huang X., Zhang X., Ai P., Zhao J., Fan X., Xu G.
Plant Physiol. 2012  159(4)  1571-81
A Constitutive Expressed Phosphate Transporter, OsPht1;1, Modulates Phosphate Uptake and Translocation in Phosphate-Replete Rice.
Wang C., Huang W., Ying Y., Li S., Secco D., Tyerman S., Whelan J., Shou H.
New Phytol. 2012  196(1)  139-48
Functional characterization of the rice SPX-MFS family reveals a key role of OsSPX-mfs1 in controlling phosphate homeostasis in leaves.
Chen J., Liu Y., Ni J., Wang Y., Bai Y., Shi J., Gan J., Wu Z., Wu P.
Plant Physiol. 2011  157(1)  269-78
OsPHF1 regulates the plasma membrane localization of low- and high-affinity inorganic phosphate transporters and determines inorganic phosphate uptake and translocation in rice.
Wu Z. , Ren H. , McGrath S.P. , Wu P. , Zhao F.J.
Plant Physiol. 2011  157(1)  498-508
Investigating the Contribution of the Phosphate Transport Pathway to Arsenic Accumulation in Rice.
Zhang Q., Wang C., Tian J., Li K., Shou H.
Plant Biol. 2011  13  7-15
Identification of rice purple acid phosphatases related to posphate starvation signalling
Liu F., Wang Z., Ren H., Shen C., Li Y., Hong-Qing Ling, Wu C., Lian X., WU P.
Plant J. 2010  62(3)  508-17
OsSPX1 suppresses the function of OsPHR2 in the regulation of expression of OsPT2 and phosphate homeostasis in shoots of rice.
Wu P., Xu J.
Plant Signaling and Behavior 2010  5  712-714
Does OsPHR2, central Pi-signaling regulator, regulate some unknown factors crucial for plant growth?
Zhou J, Jiao F, Wu Z, Li Y, Wang X, He X, Zhong W, Wu P.
Plant Physiol. 2008  146(4)  1673-86.
OsPHR2 Is Involved in Phosphate-Starvation Signaling and Excessive Phosphate Accumulation in Shoots of Plants.
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DB Reference
Gramene ID -
Gene Ontology defense response to bacterium( GO:0042742 )
inositol phosphate-mediated signaling( GO:0048016 )
phosphate ion homeostasis( GO:0055062 )
transcription factor activity( GO:0003700 )
anion homeostasis( GO:0055081 )
root hair elongation( GO:0048767 )
response to starvation( GO:0042594 )
nucleus( GO:0005634 )
cytoplasm( GO:0005737 )
response to nitrate( GO:0010167 )
phosphorus utilization( GO:0006794 )
nitrogen utilization( GO:0019740 )
phosphate transport( GO:0006817 )
DNA binding( GO:0003677 )
chromatin binding( GO:0003682 )
cellular response to phosphate starvation( GO:0016036 )
Trait Ontology abiotic stress trait( TO:0000168 )
root hair length( TO:0002665 )
phosphorus sensitivity( TO:0000102 )
bacterial blight disease resistance( TO:0000175 )
Plant Ontology 5 root hair formation stage( PO:0007519 )
Related Strains
Phenotype images
Last updated
Nov 7, 2023