|
Basic Information
|
|
CGSNL Gene Symbol
|
IRT2
|
|
Gene Symbol Synonym
|
OsIRT2, OsIRT1, OsZIP15, ZIP15
|
|
CGSNL Gene Name
|
IRON-REGULATED TRANSPORTER 2
|
|
Gene Name Synonym
|
IRON-REGULATED TRANSPORTER2, Zinc- and iron-regulating transport-like protein 15, Zn- and Fe-regulating transport-like protein 15
|
|
Protein Name
|
IRON-REGULATED TRANSPORTER 2
|
|
Allele
|
|
|
Chromosome No.
|
3
|
|
Explanation
|
AB126086. Q6L8G1. D49213. CI162465. OsIRT1 in Kobayashi et al. 2005, Regon et al. 2022. TO:0006049: iron concentration. TO:0006053: zinc concentration. TO:0020090: zinc content trait. GO:1990641: response to iron ion starvation. TO:0006059: cadmium content trait. GO: 0120127: response to zinc ion starvation.
|
|
Trait Class
|
Biochemical character
Tolerance and resistance - Stress tolerance
|
|
Expression
|
|
|
Sequence/Locus
|
|
cDNA Accession No.
|
AB126086
|
|
MSU ID
|
LOC_Os03g46454.1
|
|
RAP ID
|
Os03g0667300
|
|
Links
|
Oryzabase Chromosome View
(
IRGSP 1.0
/
Build5
)
RAP-DB
(
IRGSP 1.0
/
Build5
)
Related IDs List (
IRGSP 1.0
/
Build5
)
|
INSD Accession List
(Test version)
|
-
|
|
Map
|
|
Locate(cM)
|
|
|
Link map
|
Classical linkage map
|
|
References
|
|
Wang W., He F., Zhang H., Yang Y., Wang X., Fu Y., Shou H., Zheng L.
Abiotech 2025 6(2) 215-231
OsbHLH062 regulates iron homeostasis by inhibiting iron deficiency responses in rice.
|
|
Shahzad M., Peng D., Khan A., Ayyaz A., Askri S.M.H., Naz S., Huang B., Zhang G.
Ecotoxicol. Environ. Saf. 2024 288 117386
Sufficient manganese supply is necessary for OsNramp5 knockout rice plants to ensure normal growth and less Cd uptake.
|
|
Zeng X., Yang S., Li F., Yao Y., Wu Z., Xue Y., Liu Y.
Genes (Basel) 2024 15(6)
Genome-Wide Identification of <i>OsZIPs</i> in Rice and Gene Expression Analysis under Manganese and Selenium Stress.
|
|
Regon P., Dey S., Rehman M., Pradhan A.K., Chowra U., Tanti B., Talukdar A.D., Panda S.K.
Front Plant Sci 2022 13 798580
Transcriptomic Analysis Revealed Reactive Oxygen Species Scavenging Mechanisms Associated With Ferrous Iron Toxicity in Aromatic Keteki Joha Rice.
|
|
Zhang J., Zhu Y., Yu L., Yang M., Zou X., Yin C., Lin Y.
Cells 2022 11(3)
Research Advances in Cadmium Uptake, Transport and Resistance in Rice (<i>Oryza sativa</i> L.).
|
|
Zhan J., Zou W., Li S., Tang J., Lu X., Meng L., Ye G.
Int J Mol Sci 2022 23(19)
OsNAC15 Regulates Tolerance to Zinc Deficiency and Cadmium by Binding to <i>OsZIP7</i> and <i>OsZIP10</i> in Rice.
|
|
Chowdhury R., Nallusamy S., Shanmugam V., Loganathan A., Muthurajan R., Subramanian Kizhaeral Sivathapandian, Paramasivam J., Duraialagaraja S.
Biologia 2022 77 39-53
Genome‐wide understanding of evolutionary and functional relationships of rice Yellow Stripe‐Like (YSL) transporter family in comparison with other plant species
|
|
Tang L., Dong J., Tan L., Ji Z., Li Y., Sun Y., Chen C., Lv Q., Mao B., Hu Y., Zhao B.
Rice (N Y) 2021 14(1) 89
Overexpression of OsLCT2, a Low-Affinity cation transporter Gene, Reduces Cadmium Accumulation in Shoots and Grains of Rice.
|
|
Liu J., Zhan J., Chen J., Lu X., Zhi S., Ye G.
Front Genet 2021 12 701658
Validation of Genes Affecting Rice Grain Zinc Content Through Candidate Gene-Based Association Analysis.
|
|
Wang M., Hasegawa T., Beier M., Hayashi M., Ohmori Y., Yano K., Teramoto S., Kamiya T., Fujiwara T.
Plant Cell Physiol. 2021
Growth and nitrate reductase activity are impaired in rice OsNLP4 mutantssupplied with nitrate.
|
|
Liang G., Zhang H., Li Y., Pu M., Yang Y., Li C., Lu C., Xu P., Yu D.
J Integr Plant Biol 2020 62(5) 668-689
Oryza sativa FER-LIKE FE DEFICIENCY-INDUCED TRANSCRIPTION FACTOR (OsFIT/OsbHLH156) interacts with OsIRO2 to regulate iron homeostasis.
|
|
Che J., Yokosho K., Yamaji N., Jian Feng Ma
Plant Physiol. 2019 181(1) 276-288
A Vacuolar Phytosiderophore Transporter Alters Iron and Zinc Accumulation in Polished Rice Grains.
|
|
Zheng X., Chen L., Li X.
Botanical Studies 2018 59(1) 22
Arabidopsis and rice showed a distinct pattern in ZIPs genes expression profile in response to Cd stress.
|
|
Tanaka N., Uraguchi S., Kajikawa M., Saito A., Ohmori Y., Fujiwara T.
Plant J. 2018 96(5) 997-1006
A rice PHD-finger protein OsTITANIA, is a growth regulator that functions through elevating expression of transporter genes for multiple metals.
|
|
Zhang H., Li Y., Yao X., Liang G., Yu D.
Plant Physiol. 2017 175(1) 543-554
POSITIVE REGULATOR OF IRON HOMEOSTASIS1, OsPRI1, Facilitates Iron Homeostasis.
|
|
Bashir K., Ishimaru Y., Itai R.N., Senoura T., Takahashi M., An G., Oikawa T., Ueda M., Sato A., Uozumi N., Nakanishi H., Nishizawa N.K.
Plant Mol. Biol. 2015 88(1-2) 165-76
Iron deficiency regulated OsOPT7 is essential for iron homeostasis in rice.
|
|
Sebastian A., Prasad M.N.
Protoplasma 2015
Operative photo assimilation associated proteome modulations are critical for iron-dependent cadmium tolerance in Oryza sativa L.
|
|
Agarwal S., Tripura Venkata VG., Kotla A., Mangrauthia S.K., Neelamraju S.
Gene 2014 546(2) 430-6
Expression patterns of QTL based and other candidate genes in Madhukar × Swarna RILs with contrasting levels of iron and zinc in unpolished rice grains.
|
|
Kobayashi T.a b, Nakanishi Itai R.c, Nishizawa N.K.b
Rice 2014 7
Iron deficiency responses in rice roots
|
|
Takahashi R., Ishimaru Y., Shimo H., Bashir K., Senoura T., Sugimoto K., Ono K., Suzui N., Kawachi N., Ishii S., Yin Y.G., Fujimaki S., Yano M., Nishizawa N.K., Nakanishi H.
PLoS ONE 2014 9(6) e98816
From laboratory to field: OsNRAMP5-knockdown rice is a promising candidate for Cd phytoremediation in paddy fields.
|
|
Lee S., Kim Y.S., Jeon U.S., Kim Y.K., Schjoerring J.K., An G.
Mol. Cells 2012 33(3) 269-75
Activation of Rice nicotianamine synthase 2 (OsNAS2) enhances iron availability for biofortification.
|
|
Wang L., Ying Y., Narsai R., Ye L., Zheng L., Tian J., Whelan J., Shou H.
Plant Cell Environ. 2012 36(1) 224-36.
Identification of OsbHLH133 as a regulator of iron distribution between roots and shoots in Oryza sativa.
|
|
Takahashi R., Ishimaru Y., Nakanishi H., Nishizawa N.K.
Plant Signal Behav 2011 6(11)
Role of the iron transporter OsNRAMP1 in cadmium uptake and accumulation in rice.
|
|
Oda K., Otani M., Uraguchi S., Akihiro T., Fujiwara T.
Bioscience, Biotechnology and Biochemistry 2011 75 1211-1213
Rice ABCG43 is Cd inducible and confers Cd tolerance on yeast
|
|
Takanashi H., Ishimaru Y., Bashir K., Fujimoto M., Shimo H., An G., Nagasaka S., Nishizawa N.K., Nakanishi H., Tsutsumi N.
Nature Communications 2011 2 322
The rice mitochondrial iron transporter is essential for plant growth
|
|
Nakanishi H., Ogawa I., Ishimaru Y., Mori S., Nishizawa N.
Soil Sci. Plant Nutr. 2006 52(4) 464 469
Iron deficiency enhances cadmium uptake and translocation mediated by the Fe^<2+> transporters OsIRT1 and OsIRT2 in rice
|
|
Ishimaru,Y., Suzuki,M., Tsukamoto,T., Suzuki,K., Nakazono,M., Kobayashi,T., Wada,Y., Watanabe,S., Matsuhashi,S., Takahashi,M., Nakanishi,H., Mori,S. and Nishizawa,N.K.
Plant J. 2006 45(3) 335-346
Rice plants take up iron as an Fe3+-phytosiderophore and as Fe2+
|
|
Kobayashi,T., Suzuki,M., Inoue,H., Itai,R.N., Takahashi,M., Nakanishi,H., Mori,S. and Nishizawa,N.K.
J. Exp. Bot. 2005 56 1305-1316
Expression of iron-acquisition-related genes in iron-deficient rice is co-ordinately induced by partially conserved iron-deficiency-responsive elements
|
|
DB Reference
|
|
Gramene ID
|
-
|
|
Ontologies
|
|
Gene Ontology
|
response to selenium ion( GO:0010269 )
response to manganese ion( GO:0010042 )
membrane( GO:0016020 )
plasma membrane( GO:0005886 )
zinc ion transmembrane transporter activity( GO:0005385 )
cadmium ion transmembrane transport( GO:0070574 )
iron ion homeostasis( GO:0055072 )
integral to membrane( GO:0016021 )
iron ion transport( GO:0006826 )
response to cadmium ion( GO:0046686 )
|
|
Trait Ontology
|
iron sensitivity( TO:0000224 )
zinc sensitivity( TO:0000351 )
manganese sensitivity( TO:0000073 )
selenium sensitivity( TO:0000032 )
|
|
Plant Ontology
|
root( PO:0009005 )
|
|
Related Strains
|
|
-
|
|
Phenotype images
|
|
-
|
|
Last updated
|
|
Mar 17, 2026
|
Update info.