Gene - Detail

Detail of Gene

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Basic Information
CGSNL Gene Symbol PIK
Gene Symbol Synonym Pik, RMg8, Pi-k, Pik-2, Pik-1, Pik1, Pik2, Pik-H4
Gene Name Synonym Pyricularia oryzae resistance-k, Magnaporthe grisea resistance-k, Blast resistance k
Protein Name
Allele Pi k-s(Pi-s, Pik-s), Pi k-p(Pik-p), Pi k-m(Pi m, Pik-p), Pi k-h(Pik-h), Pi k-g(Pik-g), Pi1, Pik1-KA, Pik1-KU, Pik2-KA, Pik2-KU
Chromosome No. 11
Explanation Resistant to rice blast disease. Varieties 'Kanto 51' and 'Kusabue' have this gene. PO:0009047; stem ; PO:0020141; stem node ; PO:0009049; inflorescence ; PO:0009025; leaf. GRO:0007044; 06-heading stage ; GRO:0007042; 08-dough stage ; GRO:0007046; 07-milk stage ; GRO:0007048; 04-stem elongation stage ; GRO:0007047; 02-seedling ; GRO:0007049; 03-tillering stage ; GRO:0007148; 05-booting stage ; GRO:0007045; 09-mature grain stage. HM048900. AY914077. AB462256(Pikm1-TS, Pikm2-TS), AB462324(Pikm1-TS), AB462325(Pikm2-TS). Pikm-specific resistance is conferred by cooperation of Pikm1-TS and Pikm2-TS (Ashikawa et al. 2008). HM048900 (Pik-2, Pik-1). A combination of Pik-1 and Pik-2 is required for the expression of Pik resistance (Zhai et al. 2011). HM035360 (Pikp-1, Pikp-2). Both Pikp-1 and Pikp-2 are required for Pik-p function (Yuan et al. 2011). The original lines of each allele are as follows: Pi-kp from Pusur (the West Pakistani rice variety), Pi-kh from HR-22 (an Indian variety), Pi-ks in Shinriki, Pi-km in Minehikari and Pi-kg(t) in GA20. Pi-kh was renamed Pi54, because Pi-kh is ~2.5Mbp away from the Pik Locus (Sharma et al. 2010). Pi1 is an allele at the Pik locus. Like other alleles at this locus, Pi1 consists of two genes: Pi1-5C and Pi1-6C (HQ606329) (Hua et al. 2012). AB616658 (Pik1-KA), AB616659 (Pik2-KA, Pik1-KA). Pik-H4 is an allele of the major resistance (R) gene Pi-k which consists of two adjacent nucleotide-binding domain and leucine- rich repeat (NLR) genes, Pik1 -H4 and Pik2 -H4 (Liu et al. 2017).
Trait Class Tolerance and resistance - Disease resistance
cDNA Accession No. -
RAP ID Os11g0689000/Os11g0689100
Links Oryzabase Chromosome View ( IRGSP 1.0 / Build5 )
RAP-DB ( IRGSP 1.0 / Build5 )
Related IDs List ( IRGSP 1.0 / Build5 )
INSD Accession List
(Test version)
Link to INSD Accession List
Locate(cM) 141.0
Link map Classical linkage map
Reinke R., Kim S.M., Kim B.K.
Mol. Genet. Genomics 2018  293(6)  1565-1575
Developing japonica rice introgression lines with multiple resistance genes for brown planthopper, bacterial blight, rice blast, and rice stripe virus using molecular breeding.
Yadav M.K., S A., Ngangkham U., Shubudhi H.N., Bag M.K., Adak T., Munda S., Samantaray S., Jena M.
PLoS ONE 2017  12(4)  e0176236
Use of molecular markers in identification and characterization of resistance to rice blast in India.
Liu H., Dong S., Gu F., Liu W., Yang G., Huang M., Xiao W., Liu Y., Guo T., Wang H., Chen Z., Wang J.
Front Plant Sci 2017  8  127
NBS-LRR Protein Pik-H4 Interacts with OsBIHD1 to Balance Rice Blast Resistance and Growth by Coordinating Ethylene-Brassinosteroid Pathway.
Imam J.a b, Alam S.a, Mandal N.P.a, Variar M.a, Shukla P.b
Euphytica 2014  196  199-211
Molecular screening for identification of blast resistance genes in North East and Eastern Indian rice germplasm (Oryza sativa L.) with PCR based makers
Miah G., Rafii M.Y., R .Ismail M., B. Puteh A., A. Rahim H., Asfaliza R., A. Latif M.
Mol. Biol. Rep. 2013  40(3)  2369-88
Blast resistance in rice: a review of conventional breeding to molecular approaches
Luo,S., Zhang,Y., Hu,Q., Chen,J., Li,K., Lu,C., Liu,H., Wang,W. and Kuang,H.
Plant Physiol. 2012  159(1)  197-210
Dynamic Nucleotide-Binding-Site and Leucine-Rich-Repeat- encoding Genes in the Grass Family
Ashikawa,I., Hayashi,N., Abe,F., Wu,J. and Matsumoto,T.
Mol. Breed. 2012  30  485-494
Characterization of the rice blast resistance gene Pik cloned from Kanto51
Gupta S.K., Rai A.K., Kanwar S.S., Sharma T.R.
PLoS ONE 2012  7(8)  e42578
Comparative analysis of zinc finger proteins involved in plant disease resistance.
Hua L., Wu J., Chen C., Wu W., He X., Lin F., Wang Li., Ashikawa I., Matsumoto T., Wang L., Pan Q.
Theor Appl Genet (Published online) 2012  125  1047-1055
The isolation of Pi1, an allele at the Pik locus which confers broad spectrum resistance to rice blast
Sharma T.R., Rai A.K., Gupta S.K., Vijayan J., Devanna B.N., Ray S.
Agric Res 2012  1  37-52
Rice Blast Management Through Host-Plant Resistance: Retrospect and Prospects
Hua,L., Wu,J., Chen,C., Wu,W., He,X., Lin,F., Wang,L., Ashikawa,I., Matsumoto,T., Wang,L. and Pan,Q.
Theor. Appl. Genet. 2012  125(5)  1047-55
The isolation of Pi1, an allele at the Pik locus which confers broad spectrum resistance to rice blast
Zhai,C., Lin,F., Dong,Z., He,X., Yuan,B., Zeng,X., Wang,L. and Pan,Q.
New Phytol. 2011  189(1)  321-334
The isolation and characterization of Pik, a rice blast resistance gene which emerged after rice domestication
Jia Y., Moldenhauer K.
Journal of Plant Registrations, 2010  4  163-166
Development of Monogenic and Digenic Rice Lines for Blast Resistance Genes Pi-ta, Pi-kh/Pi-ks
Costanzo,S. and Jia,Y.
Plant Sci. 2010  178(6)  523-530
Sequence variation at the rice blast resistance gene Pi-km locus: Implications for the development of allele specific markers
Yuan B,Zhai C,Wang W,Zeng X,Xu X,Hu H,Lin F,Wang L,Pan Q
Theor. Appl. Genet. 2010  122(5)  1017-28
The Pik-p resistance to Magnaporthe oryzae in rice is mediated by a pair of closely linked CC-NBS-LRR genes.
Sharma T.R., Rai A.K., Gupta S.K., Singh N.K.
J. Plant Biochem. Biotechnol. 2010  19  87-89
Broad-spectrum blast resistance gene Pi-kh cloned from rice line Tetep designated as Pi54.
Wang L., Xu X., Lin F., Pan Q.
Phytopathology 2009  99(8)  900-5
Characterization of rice blast resistance genes in the Pik cluster and fine mapping of the Pik-p locus.
Jia Y., Lee F.N., McClung A.
Plant Dis. 2009  93  639-644
Determination of Resistance Spectra of the Pi-ta and Pi-k Genes to U.S. Races of Magnaporthe oryzae Causing Rice Blast in a Recombinant Inbred Line Population
Koide Y., Kobayashi N., Xu D., Fukuta Y.
JARQ 2009  43  255-280
Resistance Genes and Selection DNA Markers for Blast Disease in Rice (Oryza sativa L.)
Ballini E., Morel J.B., Droc G., Price A., Courtois B., Notteghem J.L., Tharreau D.
Mol. Plant Microbe Interact. 2008  21(7)  859-68
A genome-wide meta-analysis of rice blast resistance genes and quantitative trait loci provides new insights into partial and complete resistance.
Ashikawa,I., Hayashi,N., Yamane,H., Kanamori,H., Wu,J., Matsumoto,T., Ono,K. and Yano,M.
Genetics 2008  180(4)  2267-2276
Two adjacent nucleotide-binding site-leucine-rich repeat class genes are required to confer Pikm-specific rice blast resistance
Li L.Y., Wang L., Jing J.X., Li Z.Q., Lin F., Huang L.F., Pan Q.H.
Mol Breeding 2007  20  179-188
The Pikm gene, conferring stable resistance to isolates of Magnaporthe oryzae, was finely mapped in a crossover-cold region on rice chromosome 11
Cho Y.C., Kwon S.W., Choi I.S., Lee S.K., Jeon J.S., Oh M.K., Roh J.H., Hwang H.G., Yang S.J., Kim Y.G.
J. Crop Sci. Biotech. 2007  10  265-276
Identification of Major Blast Resistance Genes in Korean Rice Varieties (Oryza sativa L.) Using Molecular Markers
Hayashi K, Yoshida H, Ashikawa I.
Theor. Appl. Genet. 2006  113(2)  251-260
Development of PCR-based allele-specific and InDel marker sets for nine rice blast resistance genes.
Sharma,T.R., Madhav,M.S., Singh,B.K., Shanker,P., Jana,T.K., Dalal,V., Pandit,A., Singh,A., Gaikwad,K., Upreti,H.C. and Singh,N.K.
Molecular Genetics & Genomics (Molecular General Genetics up to 2001) 2005  274(6)  569-578
High-resolution mapping, cloning and molecular characterization of the Pi-kh gene of rice, which confers resistance to Magnaporthe grisea.
Campbell M.A., Chen D., Ronald P.C.
Phytopathology 2004  94(3)  302-7
Development of Co-Dominant Amplified Polymorphic Sequence Markers in Rice that Flank the Magnaporthe grisea Resistance Gene Pi7(t) in Recombinant Inbred Line 29.
Robert Fjellstrom, Concetta A. Conaway-Bormans, Anna M. McClung, Marco A. Marchetti, A. obert Shank and William D. Park
Crop Sci. 2004  44  1790-1798
Development of DNA Markers Suitable for Marker Assisted Selection of Three Pi Genes Conferring esistance to Multiple Pyricularia grisea Pathotypes
Ebron L A, Fukuta Y, Imbe T, Kato H, Yanoria JMT, Tsunematsu H, Khush GS, Yokoo M.
Breeding Science 2004  54(4)  381-387
Estimation of Genes in Blast Resistance in Elite Indica-type Rice (Oryza sativa L.) Varieties-bred at the International Rice Research Institute
Muralidharan, K., D. Krishnaveni, G.S. Laha, C.S. Reddy, M. Srinivasprasad and R. Sridhar
RGN 2003  20  94-96
Evaluation of blast resistance genes in India.
Sallaud, C., M. Lorieux, E. Roumen, D Tharreau, R. Berruyer, P. Svestasrani, O. Garsmeur, A. Ghesquiere, J.L. Nottenghem
Theor. Appl. Genet. 2003  106  794-803
Identification of five new blast resistance genes in the highly blast-resistant rice variety IR64 using a QTL mapping strategy.
Bryan,G.T., Wu,K.S., Farrall,L., Jia,Y., Hershey,H.P., McAdams,S.A., Faulk,K.N., Donaldson,G.K., Tarchini,R. and Valent,B.
Plant Cell 2000  12(11)  2033-2045
tA single amino acid difference distinguishes resistant and susceptible alleles of the rice blast resistance gene Pi-ta.
Pan Q., Wang L., Tanisaka T., Ikehashi H.
Plant Pathol. 1998  47  165-170
Allelism of rice blast resistance genes in two chinese rice cultivars, and identification of two new resistance genes
Imbe, T., S. Oba, M.J.T. Yanoria and H. Tsunematsu
RGN 1997  14  60-62.
A new gene for blast resistance in rice cultivar, IR24.
Hayasaka, H., A. Miyao, M. Yano, K. Matsunaga and T. Sasaki
Breeding Science 1996  46(Suppl. 2)  68
RFLP mapping of a rice blast resistance gene Pi-k.
Kaji, R. and T. Ogawa
Breeding Science 1996  46(Suppl. 1)  70
RFLP mapping of a blast resistance gene, Pi-km, in rice.
Pan, Q.H., T. Tanisaka and H. Ikehashi
Breeding Science 1996  46(Suppl. 2)  70
Studies on the genetics and breeding of blast resistance in rice VI. Gene analysis for the blast resistance of two Yunnan native cultivars GA20 and GA25.
Kaji, R. and T. Ogawa
IRRN 1996  21(2-3)  47
RFLP mapping of blast resistance gene Pi-km in rice.
Inukai, T., R.J. Nelson, R.S. Zeigler, S. Sarkarung, D.J. Mackill, J.M. Bonman, I. Takamure and T. Kinoshita
Phytopathology 1994  84  1278-1283.
Allelism of blast resistance genes in near-isogenic lines of rice.
Kaji, R. and T. Ogawa
Japan. J. Breed. 1994  44(Suppl. 2)  181
RFLP mapping of a blast resistance gene, Pi-k in rice.
Kiyosawa S.
RGN 1984  1  95-96
Establishment of differential varieties for pathogenicity test of rice blast fungus
Goto, I., Y.L. Jaw and A.A. Baluch
Ann. Phytopath. Soc. Japan 1981  47(2)  252-254.
Genetic studies on resistance of rice plant to blast fungus.IV. Linkage analysis of four genes, Pi-a, Pi-k, Pi-z and Pi-i.
Kiyosawa, S.
Japan. J. Breed. 1978  28(4)  287-296.
Identification of blast-resistance genes in some varieties.
Kiyosawa, S.
Symposium on Rice Breeding, IRRI, Los Banos, Philippines. 1972    203-225.
Genetics of blast resistance.
Shinoda, H., K. Toriyama, T. Yunoki, A. Ezuka and Y. Sakurai
Bull. Chugoku Agric. Exp. Stn., Ser.A 1971  20  1-25.
Studies on the varietal resistance of rice to blast. 6. Linkage relationship of blast resistance genes.
Kiyosawa S.
JARQ 1971  6  8-15
Gene Analysis of Blast Resistance in Exotic Varieties of Rice
Kiyosawa, S.
Bull. Natl. Inst. Agric. Sci., Ser.D 1970  21  61-71.
Inheritance of a particular sensitivity of the variety Sekiguchi Asahi to pathogens and chemicals and linkage relationship with blast resistance genes.
Kiyosawa S.
Japan. J. Breeding 1969  19  121-128
Inheritance of blast-resistance in West Pakistani rice variety, Pusur
Kiyosawa S.
Japan. J. Breeding 1969  19  61-73
Inheritance of resistance of rice varieties to a Philippine fungus strain of Pyricularia oryzae
Kiyosawa S., Murty V.V.S.
Japan. J. Breeding 1969  19  269-276
The inheritance of blast-resistance in indian rice variety, HR-22
Kiyosawa S.
Japan. J. Breeding 1968  18  193-205
Inheritance of blast-resistance in some Chinese rice varieties and their derivatives
TextPresso Search Search textpresso for PIK ( Recent references may be retrievable, but without any warranty )
DB Reference
Gramene ID GR:0060619
Gene Ontology response to fungus( GO:0009620 )
ATP binding( GO:0005524 )
defense response( GO:0006952 )
nucleoside-triphosphatase activity( GO:0017111 )
ADP binding( GO:0043531 )
Trait Ontology leaf blast disease resistance( TO:0000468 )
panicle blast disease resistance( TO:0000477 )
potassium concentration( TO:0000513 )
Plant Ontology vascular leaf( PO:0009025 )
stem( PO:0009047 )
inflorescence( PO:0009049 )
stem node( PO:0020141 )
Related Strains
Phenotype images
Last updated
May 4, 2019