|
Basic Information
|
|
CGSNL Gene Symbol
|
PIK
|
|
Gene Symbol Synonym
|
Pik, RMg8, Pi-k, Pik-2, Pik-1, Pik1, Pik2, Pik-H4, Pikp-1, Pikh-1, Pik1-H4, Pikh-2, Pik2-H4
|
|
CGSNL Gene Name
|
PYRICULARIA ORYZAE RESISTANCE K
|
|
Gene Name Synonym
|
Pyricularia oryzae resistance-k, Magnaporthe grisea resistance-k, Pyricularia oryzae resistance kh-1, Blast resistance k, Pyricularia oryzae resistance kh-2
|
|
Protein Name
|
|
|
Allele
|
Pi k-s(Pi-s, Pik-s), Pi k-p(Pik-p), Pi k-m(Pi m, Pik-p), Pi k-h(Pik-h), Pi k-g(Pik-g), Pi1, Pik1-KA, Pik1-KU, Pik2-KA, Pik2-KU, Pikp-1SNK-EKE
|
|
Chromosome No.
|
11
|
|
Explanation
|
HQ662330 (Pikh-2 & Pikh-1). Pik-h, an allele of Pik, comprises a pair of NBS-LRR genes, Pikh-1 and Pikh-2. Pikh-1 appears to be constitutively transcribed (Zhai et al. 2014). The transcript abundance of Pikh-2 responds to pathogen challenge (Zhai et al. 2014). Pik1-H4 and Pik2-H4 in Gu et al. 2024. Resistant to rice blast disease. Varieties 'Kanto 51' and 'Kusabue' have this gene. GRO:0007044; 06-heading stage ; GRO:0007042; 08-dough stage ; GRO:0007046; 07-milk stage ; GRO:0007048; 04-stem elongation stage ; GRO:0007047; 02-seedling ; GRO:0007049; 03-tillering stage ; GRO:0007148; 05-booting stage ; GRO:0007045; 09-mature grain stage.
A combination of Pik-1 and Pik-2 is required for the expression of Pik resistance (Zhai et al. 2011). Both Pikp-1 and Pikp-2 are required for Pik-p function (Yuan et al. 2011). Pi-km is one of the alleles in the Pi-k locus. Pikm-specific resistance is conferred by cooperation of Pikm1-TS and Pikm2-TS (Ashikawa et al. 2008). Pi1 is an allele at the Pik locus. Like other alleles at this locus, Pi1 consists of two genes: Pi1-5C and Pi1-6C (Hua et al. 2012). Pik-H4 is an allele of the major resistance (R) gene Pi-k which consists of two adjacent nucleotide-binding domain and leucine- rich repeat (NLR) genes, Pik1-H4 and Pik2-H4 (Liu et al. 2017). The original lines of each allele are as follows: Pi-kp from Pusur (the West Pakistani rice variety), Pi-kh from HR-22 (an Indian variety), Pi-ks in Shinriki, Pi-km in Minehikari and Pi-kg(t) in GA20. Pi-kh was renamed Pi54, because Pi-kh is ~2.5Mbp away from the Pik Locus (Sharma et al. 2010).
Locus 1: Os11g0688832 (LOC_Os11g46200.1), symbol: Pikm1, Pikm1-TS, Pik1-KA, Pik-1, Pikp-1, Pikm5-NP, Pik1-H4, Pi1-5, sequence: AB462324(Pikm1), AB616658 (Pik1-KA), ABA95385 (Pikm5-NP), AB510251-AB510297 (Pikm1-TS variant 1~ variant 47).
Locus 2: Os11g0689100 (LOC_Os11g46210.1, AK073759, AK108692), symbol: Pikm2, Pikm2-TS, Pik2-KA, Pik-2, Pikp-2, Pikm6-NP, Pik2-H4, Pi1-6, sequence: AB462325(Pikm2), AB510298-AB510347 (Pikm2-TS variant 1~variant 50).
sequence covering both Os11g0688832 and Os11g0689100: AB462256(Pikm1-TS, Pikm2-TS), HM048900 (Pik-2, Pik-1), HM035360 (Pikp-1, Pikp-2), AB616659 (Pik2-KA, Pik1-KA), HQ606329 (Pi1-5C, Pi1-6C).
|
|
Trait Class
|
Tolerance and resistance - Disease resistance
|
|
Expression
|
|
|
Sequence/Locus
|
|
cDNA Accession No.
|
AK108692
AK073759
|
|
MSU ID
|
LOC_Os11g46200.1
LOC_Os11g46210.1
|
|
RAP ID
|
Os11g0688832/Os11g0689100
|
|
Links
|
Oryzabase Chromosome View
(
IRGSP 1.0
/
Build5
)
RAP-DB
(
IRGSP 1.0
/
Build5
)
Related IDs List (
IRGSP 1.0
/
Build5
)
|
INSD Accession List
(Test version)
|
Link to INSD Accession List
|
|
Map
|
|
Locate(cM)
|
141.0
|
|
Link map
|
Classical linkage map
|
|
References
|
|
Gu F., Han Z., Zou X., Xie H., Chen C., Huang C., Guo T., Wang J., Wang H.
Int J Mol Sci 2024 25(10)
Unveiling the Role of RNA recognition motif Proteins in Orchestrating Nucleotide-Binding Site and Leucine-Rich Repeat Protein Gene Pairs and Chloroplast Immunity Pathways: Insights into Plant Defense Mechanisms.
|
|
Maidment J.H.R., Shimizu M., Bentham A.R., Vera S., Franceschetti M., Longya A., Stevenson C.E.M., De la Concepcion JC., Białas A., Kamoun S., Terauchi R., Banfield M.J.
Elife 2023 12
Effector target-guided engineering of an integrated domain expands the disease resistance profile of a rice NLR immune receptor.
|
|
Bentham A.R., De la Concepcion JC., Benjumea J.V., Kourelis J., Jones S., Mendel M., Stubbs J., Stevenson C.E.M., Maidment J.H.R., Youles M., Zdrzałek R., Kamoun S., Banfield M.J.
Plant Cell 2023 35(10) 3809-3827
Allelic compatibility in plant immune receptors facilitates engineering of new effector recognition specificities.
|
|
Reinke R., Kim S.M., Kim B.K.
Mol. Genet. Genomics 2018 293(6) 1565-1575
Developing japonica rice introgression lines with multiple resistance genes for brown planthopper, bacterial blight, rice blast, and rice stripe virus using molecular breeding.
|
|
Liu H., Dong S., Gu F., Liu W., Yang G., Huang M., Xiao W., Liu Y., Guo T., Wang H., Chen Z., Wang J.
Front Plant Sci 2017 8 127
NBS-LRR Protein Pik-H4 Interacts with OsBIHD1 to Balance Rice Blast Resistance and Growth by Coordinating Ethylene-Brassinosteroid Pathway.
|
|
Yadav M.K., S A., Ngangkham U., Shubudhi H.N., Bag M.K., Adak T., Munda S., Samantaray S., Jena M.
PLoS ONE 2017 12(4) e0176236
Use of molecular markers in identification and characterization of resistance to rice blast in India.
|
|
Zhai C., Zhang Y., Yao N., Lin F., Liu Z., Dong Z., Wang L., Pan Q.
PLoS ONE 2014 9(6) e98067
Function and interaction of the coupled genes responsible for Pik-h encoded rice blast resistance.
|
|
Imam J.a b, Alam S.a, Mandal N.P.a, Variar M.a, Shukla P.b
Euphytica 2014 196 199-211
Molecular screening for identification of blast resistance genes in North East and Eastern Indian rice germplasm (Oryza sativa L.) with PCR based makers
|
|
Miah G., Rafii M.Y., R .Ismail M., B. Puteh A., A. Rahim H., Asfaliza R., A. Latif M.
Mol. Biol. Rep. 2013 40(3) 2369-88
Blast resistance in rice: a review of conventional breeding to molecular approaches
|
|
Gupta S.K., Rai A.K., Kanwar S.S., Sharma T.R.
PLoS ONE 2012 7(8) e42578
Comparative analysis of zinc finger proteins involved in plant disease resistance.
|
|
Sharma T.R., Rai A.K., Gupta S.K., Vijayan J., Devanna B.N., Ray S.
Agric Res 2012 1 37-52
Rice Blast Management Through Host-Plant Resistance: Retrospect and Prospects
|
|
Luo,S., Zhang,Y., Hu,Q., Chen,J., Li,K., Lu,C., Liu,H., Wang,W. and Kuang,H.
Plant Physiol. 2012 159(1) 197-210
Dynamic Nucleotide-Binding-Site and Leucine-Rich-Repeat- encoding Genes in the Grass Family
|
|
Hua L., Wu J., Chen C., Wu W., He X., Lin F., Wang Li., Ashikawa I., Matsumoto T., Wang L., Pan Q.
Theor Appl Genet (Published online) 2012 125 1047-1055
The isolation of Pi1, an allele at the Pik locus which confers broad spectrum resistance to rice blast
|
|
Ashikawa,I., Hayashi,N., Abe,F., Wu,J. and Matsumoto,T.
Mol. Breed. 2012 30 485-494
Characterization of the rice blast resistance gene Pik cloned from Kanto51
|
|
Hua,L., Wu,J., Chen,C., Wu,W., He,X., Lin,F., Wang,L., Ashikawa,I., Matsumoto,T., Wang,L. and Pan,Q.
Theor. Appl. Genet. 2012 125(5) 1047-55
The isolation of Pi1, an allele at the Pik locus which confers broad spectrum resistance to rice blast
|
|
Zhai,C., Lin,F., Dong,Z., He,X., Yuan,B., Zeng,X., Wang,L. and Pan,Q.
New Phytol. 2011 189(1) 321-334
The isolation and characterization of Pik, a rice blast resistance gene which emerged after rice domestication
|
|
Sharma T.R., Rai A.K., Gupta S.K., Singh N.K.
J. Plant Biochem. Biotechnol. 2010 19 87-89
Broad-spectrum blast resistance gene Pi-kh cloned from rice line Tetep designated as Pi54.
|
|
Yuan B,Zhai C,Wang W,Zeng X,Xu X,Hu H,Lin F,Wang L,Pan Q
Theor. Appl. Genet. 2010 122(5) 1017-28
The Pik-p resistance to Magnaporthe oryzae in rice is mediated by a pair of closely linked CC-NBS-LRR genes.
|
|
Jia Y., Moldenhauer K.
Journal of Plant Registrations, 2010 4 163-166
Development of Monogenic and Digenic Rice Lines for Blast Resistance Genes Pi-ta, Pi-kh/Pi-ks
|
|
Costanzo,S. and Jia,Y.
Plant Sci. 2010 178(6) 523-530
Sequence variation at the rice blast resistance gene Pi-km locus: Implications for the development of allele specific markers
|
|
Jia Y., Lee F.N., McClung A.
Plant Dis. 2009 93 639-644
Determination of Resistance Spectra of the Pi-ta and Pi-k Genes to U.S. Races of Magnaporthe oryzae Causing Rice Blast in a Recombinant Inbred Line Population
|
|
Koide Y., Kobayashi N., Xu D., Fukuta Y.
JARQ 2009 43 255-280
Resistance Genes and Selection DNA Markers for Blast Disease in Rice (Oryza sativa L.)
|
|
Wang L., Xu X., Lin F., Pan Q.
Phytopathology 2009 99(8) 900-5
Characterization of rice blast resistance genes in the Pik cluster and fine mapping of the Pik-p locus.
|
|
Ashikawa,I., Hayashi,N., Yamane,H., Kanamori,H., Wu,J., Matsumoto,T., Ono,K. and Yano,M.
Genetics 2008 180(4) 2267-2276
Two adjacent nucleotide-binding site-leucine-rich repeat class genes are required to confer Pikm-specific rice blast resistance
|
|
Ballini E., Morel J.B., Droc G., Price A., Courtois B., Notteghem J.L., Tharreau D.
Mol. Plant Microbe Interact. 2008 21(7) 859-68
A genome-wide meta-analysis of rice blast resistance genes and quantitative trait loci provides new insights into partial and complete resistance.
|
|
Li L.Y., Wang L., Jing J.X., Li Z.Q., Lin F., Huang L.F., Pan Q.H.
Mol Breeding 2007 20 179-188
The Pikm gene, conferring stable resistance to isolates of Magnaporthe oryzae, was finely mapped in a crossover-cold region on rice chromosome 11
|
|
Cho Y.C., Kwon S.W., Choi I.S., Lee S.K., Jeon J.S., Oh M.K., Roh J.H., Hwang H.G., Yang S.J., Kim Y.G.
J. Crop Sci. Biotech. 2007 10 265-276
Identification of Major Blast Resistance Genes in Korean Rice Varieties (Oryza sativa L.) Using Molecular Markers
|
|
Hayashi K, Yoshida H, Ashikawa I.
Theor. Appl. Genet. 2006 113(2) 251-260
Development of PCR-based allele-specific and InDel marker sets for nine rice blast resistance genes.
|
|
Sharma,T.R., Madhav,M.S., Singh,B.K., Shanker,P., Jana,T.K., Dalal,V., Pandit,A., Singh,A., Gaikwad,K., Upreti,H.C. and Singh,N.K.
Molecular Genetics & Genomics (Molecular General Genetics up to 2001) 2005 274(6) 569-578
High-resolution mapping, cloning and molecular characterization of the Pi-kh gene of rice, which confers resistance to Magnaporthe grisea.
|
|
Ebron L A, Fukuta Y, Imbe T, Kato H, Yanoria JMT, Tsunematsu H, Khush GS, Yokoo M.
Breeding Science 2004 54(4) 381-387
Estimation of Genes in Blast Resistance in Elite Indica-type Rice (Oryza sativa L.) Varieties-bred at the International Rice Research Institute
|
|
Robert Fjellstrom, Concetta A. Conaway-Bormans, Anna M. McClung, Marco A. Marchetti, A. obert Shank and William D. Park
Crop Sci. 2004 44 1790-1798
Development of DNA Markers Suitable for Marker Assisted Selection of Three Pi Genes Conferring esistance to Multiple Pyricularia grisea Pathotypes
|
|
Campbell M.A., Chen D., Ronald P.C.
Phytopathology 2004 94(3) 302-7
Development of Co-Dominant Amplified Polymorphic Sequence Markers in Rice that Flank the Magnaporthe grisea Resistance Gene Pi7(t) in Recombinant Inbred Line 29.
|
|
Muralidharan, K., D. Krishnaveni, G.S. Laha, C.S. Reddy, M. Srinivasprasad and R. Sridhar
RGN 2003 20 94-96
Evaluation of blast resistance genes in India.
|
|
Sallaud, C., M. Lorieux, E. Roumen, D Tharreau, R. Berruyer, P. Svestasrani, O. Garsmeur, A. Ghesquiere, J.L. Nottenghem
Theor. Appl. Genet. 2003 106 794-803
Identification of five new blast resistance genes in the highly blast-resistant rice variety IR64 using a QTL mapping strategy.
|
|
Bryan,G.T., Wu,K.S., Farrall,L., Jia,Y., Hershey,H.P., McAdams,S.A., Faulk,K.N., Donaldson,G.K., Tarchini,R. and Valent,B.
Plant Cell 2000 12(11) 2033-2045
tA single amino acid difference distinguishes resistant and susceptible alleles of the rice blast resistance gene Pi-ta.
|
|
Pan Q., Wang L., Tanisaka T., Ikehashi H.
Plant Pathol. 1998 47 165-170
Allelism of rice blast resistance genes in two chinese rice cultivars, and identification of two new resistance genes
|
|
Imbe, T., S. Oba, M.J.T. Yanoria and H. Tsunematsu
RGN 1997 14 60-62.
A new gene for blast resistance in rice cultivar, IR24.
|
|
Hayasaka, H., A. Miyao, M. Yano, K. Matsunaga and T. Sasaki
Breeding Science 1996 46(Suppl. 2) 68
RFLP mapping of a rice blast resistance gene Pi-k.
|
|
Kaji, R. and T. Ogawa
Breeding Science 1996 46(Suppl. 1) 70
RFLP mapping of a blast resistance gene, Pi-km, in rice.
|
|
Pan, Q.H., T. Tanisaka and H. Ikehashi
Breeding Science 1996 46(Suppl. 2) 70
Studies on the genetics and breeding of blast resistance in rice VI. Gene analysis for the blast resistance of two Yunnan native cultivars GA20 and GA25.
|
|
Kaji, R. and T. Ogawa
IRRN 1996 21(2-3) 47
RFLP mapping of blast resistance gene Pi-km in rice.
|
|
Kaji, R. and T. Ogawa
Japan. J. Breed. 1994 44(Suppl. 2) 181
RFLP mapping of a blast resistance gene, Pi-k in rice.
|
|
Inukai, T., R.J. Nelson, R.S. Zeigler, S. Sarkarung, D.J. Mackill, J.M. Bonman, I. Takamure and T. Kinoshita
Phytopathology 1994 84 1278-1283.
Allelism of blast resistance genes in near-isogenic lines of rice.
|
|
Kiyosawa S.
RGN 1984 1 95-96
Establishment of differential varieties for pathogenicity test of rice blast fungus
|
|
Goto, I., Y.L. Jaw and A.A. Baluch
Ann. Phytopath. Soc. Japan 1981 47(2) 252-254.
Genetic studies on resistance of rice plant to blast fungus.IV. Linkage analysis of four genes, Pi-a, Pi-k, Pi-z and Pi-i.
|
|
Kiyosawa, S.
Japan. J. Breed. 1978 28(4) 287-296.
Identification of blast-resistance genes in some varieties.
|
|
Kiyosawa, S.
Symposium on Rice Breeding, IRRI, Los Banos, Philippines. 1972 203-225.
Genetics of blast resistance.
|
|
Shinoda, H., K. Toriyama, T. Yunoki, A. Ezuka and Y. Sakurai
Bull. Chugoku Agric. Exp. Stn., Ser.A 1971 20 1-25.
Studies on the varietal resistance of rice to blast. 6. Linkage relationship of blast resistance genes.
|
|
Kiyosawa S.
JARQ 1971 6 8-15
Gene Analysis of Blast Resistance in Exotic Varieties of Rice
|
|
Kiyosawa, S.
Bull. Natl. Inst. Agric. Sci., Ser.D 1970 21 61-71.
Inheritance of a particular sensitivity of the variety Sekiguchi Asahi to pathogens and chemicals and linkage relationship with blast resistance genes.
|
|
Kiyosawa S.
Japan. J. Breeding 1969 19 61-73
Inheritance of resistance of rice varieties to a Philippine fungus strain of Pyricularia oryzae
|
|
Kiyosawa S., Murty V.V.S.
Japan. J. Breeding 1969 19 269-276
The inheritance of blast-resistance in indian rice variety, HR-22
|
|
Kiyosawa S.
Japan. J. Breeding 1969 19 121-128
Inheritance of blast-resistance in West Pakistani rice variety, Pusur
|
|
Kiyosawa S.
Japan. J. Breeding 1968 18 193-205
Inheritance of blast-resistance in some Chinese rice varieties and their derivatives
|
|
DB Reference
|
|
Gramene ID
|
GR:0060619
|
|
Ontologies
|
|
Gene Ontology
|
response to fungus( GO:0009620 )
ATP binding( GO:0005524 )
defense response( GO:0006952 )
nucleoside-triphosphatase activity( GO:0017111 )
ADP binding( GO:0043531 )
detection of molecule of fungal origin( GO:0032491 )
hormone-mediated signaling( GO:0009755 )
chloroplast( GO:0009507 )
vesicle( GO:0031982 )
|
|
Trait Ontology
|
blast disease( TO:0000074 )
leaf blast disease resistance( TO:0000468 )
potassium concentration( TO:0000513 )
panicle blast disease resistance( TO:0000477 )
|
|
Plant Ontology
|
stem node( PO:0020141 )
vascular leaf( PO:0009025 )
stem( PO:0009047 )
inflorescence( PO:0009049 )
|
|
Related Strains
|
|
-
|
|
Phenotype images
|
|
-
|
|
Last updated
|
|
Oct 15, 2024
|
Update info.