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Detail of Gene

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Basic Information
CGSNL Gene Symbol HKT8
Gene Symbol Synonym OsHKT8, Os-HKT1;5, OsHKT1;5, HKT1;5, SKC1, qSKC-1(t), OsSKC1
Gene Name Synonym shoot K+ concentration (QTL)-1(t)
Allele HKT1;5NB, HKT1;5K, OsHKT1;5-Ni, OsHKT1;5-NB, oshkt1;5, oshkt1;5-c1, oshkt1;5-c2, oshkt1;5-c3
Chromosome No. 1
Explanation AJ108663, DQ148410. A2WNZ9. This QTL controls shoot K+ concentration in relation to salt tolerance, being located on chromosome 1 between marker C1211 and S2139. BAF04762, ABN48306. Q0JNB6, A2WNZ9. EF589340 - EF589342. EF373553, HQ162137. JQ695808-JQ695816 (O.sativa, O. rufipogon, O. glaberrima). KU994892 (OcHKT1;5 O. coarctata HKT1;5). OsHKT1;5 in Cui et al. 2016, He et al. 2016, Chen et al. 2018, Neang et al. 2020, Ye et al. 2021, Huang et al. 2021. GO:0036376: sodium ion export across plasma membrane.
Trait Class Biochemical character
Tolerance and resistance - Stress tolerance
cDNA Accession No. AK108663
MSU ID LOC_Os01g20160.1
RAP ID Os01g0307500
Links Oryzabase Chromosome View ( IRGSP 1.0 / Build5 )
RAP-DB ( IRGSP 1.0 / Build5 )
Related IDs List ( IRGSP 1.0 / Build5 )
INSD Accession List
(Test version)
Link map Classical linkage map
Ye Y., Wang S., Wu K., Ren Y., Jiang H., Chen J., Tao L., Fu X., Liu B., Wu Y.
Rice (N Y) 2021  14(1)  19
A Semi-Dominant Mutation in OsCESA9 Improves salt tolerance and Favors Field Straw Decay Traits by Altering Cell Wall Properties in Rice.
Zhang X., Long Y., Chen X., Zhang B., Xin Y., Li L., Cao S., Liu F., Wang Z., Huang H., Zhou D., Xia J.
BMC Plant Biol. 2021  21(1)  546
A NAC transcription factor OsNAC3 positively regulates ABA response and salt tolerance in rice.
Farooq M., Park J.R., Jang Y.H., Kim E.G., Kim K.M.
Front Plant Sci 2021  12  680131
Rice Cultivars Under Salt Stress Show Differential Expression of Genes Related to the Regulation of Na+/K+ Balance.
Shanmugam S., Boyett V.A., Khodakovskaya M.
PLoS ONE 2021  16(10)  e0258171
Enhancement of drought tolerance in rice by silencing of the OsSYT-5 gene.
Liu Y., Chen X., Xue S., Quan T., Cui D., Han L., Cong W., Li M., Yun D.J., Liu B., Xu Z.Y.
Plant Biotechnol. J. 2021  19(12)  2576-2588
SET DOMAIN GROUP 721 protein functions in saline-alkaline stress tolerance in the model rice variety Kitaake.
Huang S., Hu L., Zhang S., Zhang M., Jiang W., Wu T., Du X.
Int J Mol Sci 2021  22(16) 
Rice OsWRKY50 Mediates ABA-Dependent Seed Germination and Seedling Growth, and ABA-Independent Salt Stress Tolerance.
Neang S., Goto I., Skoulding N.S., Cartagena J.A., Kano-Nakata M., Yamauchi A., Mitsuya S.
BMC Plant Biol. 2020  20(1)  502
Tissue-specific expression analysis of Na+ and Cl- transporter genes associated with salt removal ability in rice leaf sheath.
Wang Y., Wang J., Zhao X., Yang S., Huang L., Du F., Li Z., Zhao X., Fu B., Wang W.
Rice (N Y) 2020  13(1)  50
Overexpression of the Transcription Factor Gene OsSTAP1 Increases salt tolerance in Rice.
Somasundaram S., Véry AA., Vinekar R.S., Ishikawa T., Kumari K., Pulipati S., Kumaresan K., Corratgé-Faillie C., Sowdhamini R., Parida A., Shabala L., Shabala S., Venkataraman G.
Plant Cell Physiol. 2020  61(7)  1321-1334
Homology Modeling Identifies Crucial Amino-Acid Residues That Confer Higher Na+ Transport Capacity of OcHKT1;5 from Oryza coarctata Roxb.
Chakraborty K., Mondal S., Ray S., Samal P., Pradhan B., Chattopadhyay K., Kar M.K., Swain P., Sarkar R.K.
Front Plant Sci 2020  11  265
Tissue Tolerance Coupled With Ionic Discrimination Can Potentially Minimize the Energy Cost of Salinity Tolerance in Rice.
Fang C., Li K., Wu Y., Wang D., Zhou J., Liu X., Li Y., Jin C., Liu X., Mur L.A.J., Luo J.
Plant Cell Environ. 2019  42(5)  1503-1512
OsTSD2-mediated cell wall modification affects ion homeostasis and salt tolerance.
Chen H.C., Cheng W.H., Hong C.Y., Chang Y.S., Chang M.C.
Rice (N Y) 2018  11(1)  50
The transcription factor Osbhlh035 mediates seed germination and enables seedling recovery from salt stress through ABA-dependent and ABA-independent pathways, respectively.
Yang M., Lu K., Zhao F.J., Xie W., Ramakrishna P., Wang G., Du Q., Liang L., Sun C., Zhao H., Zhang Z., Liu Z., Tian J., Huang X.Y., Wang W., Dong H., Hu J., Ming L., Xing Y., Wang G., Xiao J., Salt D.E., Lian X.
Plant Cell 2018  30(11)  2720-2740
Genome-Wide Association Studies Reveal the Genetic Basis of Ionomic Variation in Rice.
Kobayashi N.I., Yamaji N., Yamamoto H., Okubo K., Ueno H., Costa A., Tanoi K., Matsumura H., Fujii-Kashino M., Horiuchi T., Nayef M.A., Shabala S., An G., Ma J.F., Horie T.
Plant J. 2017  91(4)  657-670
OsHKT1;5 mediates Na(+) exclusion in the vasculature to protect leaf blades and reproductive tissues from salt toxicity in rice.
Cui P., Liu H., Islam F., Li L., Farooq M.A., Ruan S., Zhou W.
Front Plant Sci 2016  7  1357
OsPEX11, a Peroxisomal Biogenesis Factor 11, Contributes to Salt Stress Tolerance in Oryza sativa.
He X., Li L., Xu H., Xi J., Cao X., Xu H., Rong S., Dong Y., Wang C., Chen R., Xu J., Gao X., Xu Z.
Plant Biol (Stuttg) 2016   
A rice jacalin-related mannose-binding lectin gene, OsJRL, enhances Escherichia coli viability under high salinity stress and improves salinity tolerance of rice.
Wang R., Jing W., Xiao L., Jin Y., Shen L., Zhang W.
Plant Physiol. 2015  168(3)  1076-90
The Rice High-Affinity Potassium Transporter1;1 Is Involved in Salt Tolerance and Regulated by an MYB-Type Transcription Factor.
Wu H., Ye H., Yao R., Zhang T., Xiong L.
Plant Sci. 2015  232  1-12
OsJAZ9 acts as a transcriptional regulator in jasmonate signaling and modulates salt stress tolerance in rice.
Platten J.D., Egdane J.A., Ismail A.M.
BMC Plant Biol. 2013  13  32
Salinity tolerance, Na+ exclusion and allele mining of HKT1;5 in Oryza sativa and O. glaberrima: many sources, many genes, one mechanism?
Cotsaftis,O., Plett,D., Shirley,N., Tester,M. and Hrmova,M.
PLoS ONE 2012  7 (7)  E39865
A Two-Staged Model of Na(+) Exclusion in Rice Explained by 3D Modeling of HKT Transporters and Alternative Splicing
Yang C., Zhao N., Xu C., Liu B., Shi D.
Aust J Crop Sci 2012  6  724-731
Regulation of ion homeostasis in rice subjected to salt and alkali stresses
Wang H., Wu Z., Han J., Zheng W., Yang C.
PLoS ONE 2012  7(5)  e37817
Comparison of ion balance and nitrogen metabolism in old and young leaves of alkali-stressed rice plants.
Wang H., Zhang M., Guo R., Shi D., Liu B., Lin X., Yang C.
BMC Plant Biol. 2012  12  194
Effects of salt stress on ion balance and nitrogen metabolism of old and young leaves in rice (Oryza sativa L.).
Ahmadi N., Negrão S., Katsantonis D., Frouin J., Ploux J., Letourmy P., Droc G., Babo P., Trindade H., Bruschi G., Greco R., Oliveira M.M., Piffanelli P., Courtois B.
Theor. Appl. Genet. 2011  123(6)  881-95
Targeted association analysis identified japonica rice varieties achieving Na(+)/K (+) homeostasis without the allelic make-up of the salt tolerant indica variety Nona Bokra.
Cotsaftis,O., Plett,D., Johnson,A.A., Walia,H., Wilson,C., Ismail,A.M., Close,T.J., Tester,M. and Baumann,U.
Mol Plant 2011  4(1)  25-41
Root-specific transcript profiling of contrasting rice genotypes in response to salinity stress
Kim SH,Bhat PR,Cui X,Walia H,Xu J,Wanamaker S,Ismail AM,Wilson C,Close TJ
BMC Plant Biol 2009  9  65
Detection and validation of single feature polymorphisms using RNA expression data from a rice genome array.
Platten JD, Cotsaftis O, Berthomieu P, Bohnert H, Davenport RJ, Fairbairn DJ, Horie T, Leigh RA, Lin HX, Luan S, Maser P, Pantoja O, Rodriguez-Navarro A, Schachtman DP, Schroeder JI, Sentenac H, Uozumi N, Very AA, Zhu JK, Dennis ES, Tester M.
Trends Plant Sci. 2006  11(8)  372-4.
Nomenclature for HKT transporters, key determinants of plant salinity tolerance.
Ren,Z.H., Gao,J.P., Li,L.G., Cai,X.L., Huang,W., Chao,D.Y., Zhu,M.Z., Wang,Z.Y., Luan,S. and Lin,H.X.
Nat Genet 2005  37(10)  1141-1146
A rice quantitative trait locus for salt tolerance encodes a sodium transporter.
Lin, H.X., M.Z, Zhu, M. Yano, J.P. Gao, Z.W. Liang, W.A. Su, X.H. Hu, Z.H. Ren, D.Y. Chao
Theor. Appl. Genet. 2004  108  253-260
QTLs for Na+ and K+ uptake of the shoots and roots controlling rice salt tolerance.
Garciadeblas,B., Senn,M.E., Banuelos,M.A. and Rodriguez-Navarro,A.
Plant J. 2003  34(6)  788-801
Sodium transport and HKT transporters: the rice model.
TextPresso Search Search textpresso for HKT8 ( Recent references may be retrievable, but without any warranty )
DB Reference
Gramene ID -
Gene Ontology chloride transport( GO:0006821 )
phloem transport( GO:0010233 )
response to stress( GO:0006950 )
sodium ion transport( GO:0006814 )
potassium ion transport( GO:0006813 )
potassium ion binding( GO:0030955 )
potassium ion transmembrane transporter activity( GO:0015079 )
integral to membrane( GO:0016021 )
cation transmembrane transporter activity( GO:0008324 )
response to jasmonic acid stimulus( GO:0009753 )
potassium ion homeostasis( GO:0055075 )
sodium ion homeostasis( GO:0055078 )
response to salt stress( GO:0009651 )
plasma membrane( GO:0005886 )
transmembrane transport( GO:0055085 )
sodium ion binding( GO:0031402 )
Trait Ontology jasmonic acid sensitivity( TO:0000172 )
salt tolerance( TO:0006001 )
sodium to potassium content ratio( TO:0000525 )
sodium content( TO:0000608 )
Plant Ontology xylem( PO:0005352 )
phloem( PO:0005417 )
vascular bundle( PO:0005020 )
leaf sheath( PO:0020104 )
root( PO:0009005 )
leaf( PO:0025034 )
shoot system( PO:0009006 )
Related Strains
Phenotype images
Last updated
May 26, 2022