Gene - Detail

Detail of Gene

Click here for feedback

Basic Information
CGSNL Gene Symbol TOP6A1
Gene Symbol Synonym OsTOP6A1, OsSPO11-1, OsSPO11A, SPO11-1
Gene Name Synonym topoisomerase 6 subunit A1, sporulation protein11-1, SPORULATION11-1
Allele Osspo11-1
Chromosome No. 3
Explanation GU170363(Japonica), AJ549926(Indica). AB219537. the likely ortholog of AtSPO11-1.
Trait Class Biochemical character
Reproductive organ - Pollination, fertilization, fertility - Meiosis
cDNA Accession No. AK287862
MSU ID LOC_Os03g54091.1
RAP ID Os03g0752200
Links Oryzabase Chromosome View ( IRGSP 1.0 / Build5 )
RAP-DB ( IRGSP 1.0 / Build5 )
Related IDs List ( IRGSP 1.0 / Build5 )
INSD Accession List
(Test version)
Link map Classical linkage map
Zhang C., Zhang F., Cheng X., Liu K., Tang J., Li Y., Tang D., Cheng Z., Yu H.
Plant Physiol. 2020  183(3)  1047-1057
OsATM Safeguards Accurate Repair of Meiotic Double-Strand Breaks in Rice.
Fayos I., Meunier A.C., Vernet A., Sanz S.N., Portefaix M., Lartaud M., Bastianelli G., Périn C., Nicolas A., Guiderdoni E.
J. Exp. Bot. 2020   
Assessment of the roles of OsSPO11-2 and OsSPO11-4 in rice meiosis using CRISPR/Cas9 mutagenesis.
Zhang F., Ma L., Zhang C., Du G., Shen Y., Tang D., Li Y., Yu H., Ma B., Cheng Z.
Plant Physiol. 2020  183(4)  1517-1530
The SUN Domain Proteins OsSUN1 and OsSUN2 Play Critical but Partially Redundant Roles in Meiosis.
Xue Z., Liu C., Shi W., Miao Y., Shen Y., Tang D., Li Y., You A., Xu Y., Chong K., Cheng Z.
Proc. Natl. Acad. Sci. U.S.A. 2019  116(32)  15967-15972
OsMTOPVIB is required for meiotic bipolar spindle assembly.
Xie E., Li Y., Tang D., Lv Y., Shen Y., Cheng Z.
J Integr Plant Biol 2019   
A strategy for generating rice apomixis by gene editing.
Hu Q., Zhang C., Xue Z., Ma L., Liu W., Shen Y., Ma B., Cheng Z.
Front Plant Sci 2018  9  1236
Osrad17 Is Required for Meiotic Double-Strand Break Repair and Plays a Redundant Role With OsZIP4 in Synaptonemal Complex Assembly.
Xue Z., Li Y., Zhang L., Shi W., Zhang C., Feng M., Zhang F., Tang D., Yu H., Gu M., Cheng Z.
Mol Plant 2016   
OsMTOPVIB promotes meiotic DNA double-strand break formation in rice.
Fu M., Wang C., Xue F., Higgins J., Chen M., Zhang D., Liang W.
Mol Plant 2016   
The DNA topoisomerase VI-B Subunit OsMTOPVIB Is Essential for Meiotic Recombination Initiation in Rice.
Ji J., Tang D., Wang M., Li Y., Zhang L., Wang K., Li M., Cheng Z.
Chromosoma 2013  122(5)  363-76
MRE11 is required for homologous synapsis and DSB processing in rice meiosis.
Miao C., Tang D., Zhang H., Wang M., Li Y., Tang S., Yu H., Gu M., Cheng Z.
Plant Cell 2013  25(8)  2998-3009
CENTRAL REGION COMPONENT1, a Novel Synaptonemal Complex Component, Is Essential for Meiotic Recombination Initiation in Rice.
Ji J., Tang D., Wang K., Wang M., Che L., Li M., Cheng Z.
Plant J. 2012  72(1)  18-30
The role of OsCOM1 in homologous chromosome synapsis and recombination in rice meiosis.
Hong L., Tang D., Zhu K., Wang K., Li M., Cheng Z.
Plant Cell 2012  24(2)  577-88
Somatic and reproductive cell development in rice anther is regulated by a putative glutaredoxin.
Shingu Y., Tokai T., Agawa Y., Toyota K., Ahamed S., Kawagishi-Kobayashi M., Komatsu A., Mikawa T., Yamamoto M.T., Wakasa K., Shibata T., Kusano K.
BMC Mol. Biol. 2012  13  1
The double-stranded break-forming activity of plant SPO11s and a novel rice SPO11 revealed by a Drosophila bioassay.
An,X.J., Deng,Z.Y. and Wang,T.
PLoS One 2011  6 (5)  e20327
OsSpo11-4, a Rice Homologue of the Archaeal TopVIA Protein, Mediates Double-Strand DNA Cleavage and Interacts with OsTopVIB
Tang X., Zhang Z.-Y., Zhang W.-J., Zhao X.-M., Li X., Zhang D., Liu Q.-Q., Tang W.-H.
Plant Physiol. 2010  154(4)  1855-1870
Global gene profiling of laser-captured pollen mother cells indicates molecular pathways and gene subfamilies involved in rice meiosis.
Yu H., Wang M., Tang D., Wang K., Chen F., Gong Z., Gu M., Cheng Z.
Chromosoma 2010  119(6)  625-36
OsSPO11-1 is essential for both homologous chromosome pairing and crossover formation in rice.
Jain M, Tyagi AK, Khurana JP.
Plant Cell Rep. 2008  27(4)  767-78.
Constitutive expression of a meiotic recombination protein gene homolog, OsTOP6A1, from rice confers abiotic stress tolerance in transgenic Arabidopsis plants.
Jain,M., Tyagi,A.K. and Khurana,J.P.
FEBS J. 2006  273(23)  5245-5260
Overexpression of putative topoisomerase 6 genes from rice confers stress tolerance in transgenic Arabidopsis plants
TextPresso Search Search textpresso for TOP6A1 ( Recent references may be retrievable, but without any warranty )
DB Reference
Gramene ID -
Gene Ontology homologous chromosome segregation( GO:0045143 )
synapsis( GO:0007129 )
meiotic cell cycle( GO:0051321 )
DNA topoisomerase activity( GO:0003916 )
DNA binding( GO:0003677 )
meiotic DNA double-strand break processing( GO:0000706 )
ATP binding( GO:0005524 )
nucleus( GO:0005634 )
chromosome( GO:0005694 )
isomerase activity( GO:0016853 )
maintenance of meiotic sister chromatid cohesion( GO:0034090 )
response to water deprivation( GO:0009414 )
response to salt stress( GO:0009651 )
meiotic DNA double-strand break formation( GO:0042138 )
chiasma formation( GO:0051026 )
reciprocal meiotic recombination( GO:0007131 )
Trait Ontology sterility related trait( TO:0000485 )
Plant Ontology -
Related Strains
Phenotype images
Last updated
Jan 19, 2022