Gene - Detail

Detail of Gene

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Basic Information
CGSNL Gene Symbol AGPL2
Gene Symbol Synonym OsAGPL2, osagpl2, APL2, OsAPL2, AGPiso, sh2, Sh2, GIF2, GAS1
Gene Name Synonym sativa ADP-glucose pyrophosphorylase large subunit 2, ADP-glucose Pyrophosphorylase large subunit 2, AGPase large subunit 2, AGPase large unit 2, ADP-glucose pyrophosphorylase subunit SH2, GRAIN INCOMPLETE FILLING 2
Allele osagpl2, osagpl2-3, osagpl2-1, gif2
Chromosome No. 1
Explanation EC= Adenosine diphosphate glucose pyrophosphorylase. AP004317. PO:0009089; endosperm. U66041. AY028314. U87450. HQ679247-HQ679415 (O. sativa and other wild rice species). U70541 (AAB58473). a homolog of maize sh2 gene. GO:2000034: regulation of seed maturation.
Trait Class Seed - Physiological traits - Storage substances
Seed - Morphological traits - Endosperm
Character as QTL - Yield and productivity
Tolerance and resistance - Stress tolerance
Biochemical character
cDNA Accession No. AK071497
MSU ID LOC_Os01g44220.1
RAP ID Os01g0633100
Links Oryzabase Chromosome View ( IRGSP 1.0 / Build5 )
RAP-DB ( IRGSP 1.0 / Build5 )
Related IDs List ( IRGSP 1.0 / Build5 )
INSD Accession List
(Test version)
Link map Classical linkage map
Sun C., Wang Y., Yang X., Tang L., Wan C., Liu J., Chen C., Zhang H., He C., Liu C., Wang Q., Zhang K., Zhang W., Yang B., Li S., Zhu J., Sun Y., Li W., Zhou Y., Wang P., Deng X.
Plant Biotechnol. J. 2023  21(3)  621-634
MATE transporter GFD1 cooperates with sugar transporters, mediates carbohydrate partitioning and controls grain-filling duration, grain size and number in rice.
Liu Z., Li P., Yu L., Hu Y., Du A., Fu X., Wu C., Luo D., Hu B., Dong H., Jiang H., Ma X., Huang W., Yang X., Tu S., Li H.
Int J Mol Sci 2023  24(9) 
<i>OsMADS1</i> Regulates Grain Quality, Gene Expressions, and Regulatory Networks of Starch and Storage Protein Metabolisms in Rice.
Jin S.K., Zhang M.Q., Leng Y.J., Xu L.N., Jia S.W., Wang S.L., Song T., Wang R.A., Yang Q.Q., Tao T., Cai X.L., Gao J.P.
Front Plant Sci 2022  13  905148
<i>OsNAC129</i> Regulates Seed Development and Plant Growth and Participates in the Brassinosteroid Signaling Pathway.
Cao R., Zhao S., Jiao G., Duan Y., Ma L., Dong N., Lu F., Zhu M., Shao G., Hu S., Sheng Z., Zhang J., Tang S., Wei X., Hu P.
Plant Commun 2022  3(6)  100463
OPAQUE3, encoding a transmembrane bZIP transcription factor, regulates endosperm storage protein and starch biosynthesis in rice.
Teng Z., Zheng Q., Liu B., Meng S., Zhang J., Ye N.
Int J Mol Sci 2022  23(14) 
Moderate Soil Drying-Induced Alternative Splicing Provides a Potential Novel Approach for the Regulation of Grain Filling in Rice Inferior Spikelets.
Ma B., Zhang L., Gao Q., Wang J., Li X., Wang H., Liu Y., Lin H., Liu J., Wang X., Li Q., Deng Y., Tang W., Luan S., He Z.
Nat. Genet. 2021  53(6)  906-915
A plasma membrane transporter coordinates phosphate reallocation and grain filling in cereals.
Liu X., Luo J., Li T., Yang H., Wang P., Su L., Zheng Y., Bao C., Zhou C.
Rice (N Y) 2021  14(1)  25
SDG711 Is Involved in Rice Seed Development through Regulation of Starch Metabolism Gene Expression in Coordination with Other Histone Modifications.
Hu L., Tu B., Yang W., Yuan H., Li J., Guo L., Zheng L., Chen W., Zhu X., Wang Y., Qin P., Ma B., Li S.
Plant Physiol. 2020  183(3)  1073-1087
Mitochondria-Associated pyruvate kinase Complexes Regulate Grain Filling in Rice.
Baysal C., He W., Drapal M., Villorbina G., Medina V., Capell T., Khush G.S., Zhu C., Fraser P.D., Christou P.
Proc. Natl. Acad. Sci. U.S.A. 2020  117(42)  26503-26512
Inactivation of rice starch branching enzyme IIb triggers broad and unexpected changes in metabolism by transcriptional reprogramming.
Paul P., Dhatt B.K., Miller M., Folsom J.J., Wang Z., Krassovskaya I., Liu K., Sandhu J., Yu H., Zhang C., Obata T., Staswick P., Walia H.
Plant Physiol. 2020  182(2)  933-948
<i>MADS78</i> and <i>MADS79</i> Are Essential Regulators of Early Seed Development in Rice.
Wang J., Chen Z., Zhang Q., Meng S., Wei C.
Plant Physiol. 2020  184(4)  1775-1791
The NAC Transcription Factors OsNAC20 and OsNAC26 Regulate Starch and Storage Protein Synthesis.
Chen C., He B., Liu X., Ma X., Liu Y., Yao H.Y., Zhang P., Yin J., Wei X., Koh H.J., Yang C., Xue H.W., Fang Z., Qiao Y.
Plant Biotechnol. J. 2019   
Pyrophosphate-fructose 6-phosphate 1-phosphotransferase (PFP1) regulates starch biosynthesis and seed development via heterotetramer formation in rice (Oryza sativa L.).
Xiong Y., Ren Y., Li W., Wu F., Yang W., Huang X., Yao J.
J. Exp. Bot. 2019  70(15)  3765-3780
NF-YC12 is a key multi-functional regulator of accumulation of seed storage substances in rice.
Pérez L., Soto E., Villorbina G., Bassie L., Medina V., Muñoz P., Capell T., Zhu C., Christou P., Farré G.
Transgenic Res. 2018  27(5)  423-439
CRISPR/Cas9-induced monoallelic mutations in the cytosolic AGPase large subunit gene APL2 induce the ectopic expression of APL2 and the corresponding small subunit gene APS2b in rice leaves.
Long W., Wang Y., Zhu S., Jing W., Wang Y., Ren Y., Tian Y., Liu S., Liu X., Chen L., Wang D., Zhong M., Zhang Y., Hu T., Zhu J., Hao Y., Zhu X., Zhang W., Wang C., Zhang W., Wan J.
Plant Physiol. 2018  177(2)  698-712
FLOURY shrunken endosperm1 Connects Phospholipid Metabolism and Amyloplast Development in Rice.
Xu E., Chen M., He H., Zhan C., Cheng Y., Zhang H., Wang Z.
Front Plant Sci 2016  7  2006
Proteomic Analysis Reveals Proteins Involved in Seed Imbibition under Salt Stress in Rice.
Wei X., Jiao G., Lin H., Sheng Z., Shao G., Xie L., Tang S., Xu Q., Hu P.
J Integr Plant Biol 2016   
GRAIN INCOMPLETE FILLING 2 regulates grain filling and starch synthesis during rice caryopsis development.
Yang J., Kim S.R., Lee S.K., Choi H., Jeon J.S., An G.
Plant Sci. 2015  240  79-89
Alanine aminotransferase 1 (OsAlaAT1) plays an essential role in the regulation of starch storage in rice endosperm.
Wu Y.P., Pu C.H., Lin H.Y., Huang H.Y., Huang Y.C., Hong C.Y., Chang M.C., Lin Y.R.
Plant Sci. 2015  233  44-52
Three novel alleles of FLOURY ENDOSPERM2 (flo2) confer dull grains with low amylose content in rice.
Tuncel A., Kawaguchi J., Ihara Y., Matsusaka H., Nishi A., Nakamura T., Kuhara S., Hirakawa H., Nakamura Y., Cakir B., Nagamine A., Okita T.W., Hwang S.K., Satoh H.
Plant Cell Physiol. 2014  55(6)  1169-83
The rice endosperm ADP-glucose pyrophosphorylase large subunit is essential for optimal catalysis and allosteric regulation of the heterotetrameric enzyme.
Lu F.H., Park Y.J.
Genet Res (Camb) 2012  94  179-189
Sequence variations in OsAGPase significantly associated with amylose content and viscosity properties in rice (Oryza sativa L.)
Zhang D., Wu J., Zhang Y., Shi C.
Plant Molecular Biology Reporter 2012  30  1303-1312
Phenotypic and Candidate Gene Analysis of a New floury endosperm Mutant (osagpl2-3) in Rice
Yan CJ,Tian ZX,Fang YW,Yang YC,Li J,Zeng SY,Gu SL,Xu CW,Tang SZ,Gu MH
Theor. Appl. Genet. 2011  122(1)  63-76
Genetic analysis of starch paste viscosity parameters in glutinous rice (Oryza sativa L.).
Yu,G., Olsen,K.M. and Schaal,B.A.
Mol. Biol. Evol. 2011  28(1)  659-671
Molecular Evolution of the Endosperm Starch Synthesis Pathway Genes in Rice (Oryza sativa L.) and Its Wild Ancestor, O. rufipogon L
Li C., Wang Y., Liu L., Hu Y., Zhang F., Mergen S., Wang G., Schläppi MR., Chu C.
PLoS Genet. 2011  7(7)  e1002196
A rice plastidial nucleotide sugar epimerase is involved in galactolipid biosynthesis and improves photosynthetic efficiency.
Zhang J,Nallamilli BR,Mujahid H,Peng Z
Plant J. 2010  64(4)  604-17
OsMADS6 plays an essential role in endosperm nutrient accumulation and is subject to epigenetic regulation in rice (Oryza sativa).
Tian,Z., Qian,Q., Liu,Q., Yan,M., Liu,X., Yan,C., Liu,G., Gao,Z., Tang,S., Zeng,D., Wang,Y., Yu,J., Gu,M. and Li,J.
Proc. Natl. Acad. Sci. U.S.A. 2009  106(51)  21760-5
Allelic diversities in rice starch biosynthesis lead to a diverse array of rice eating and cooking qualities
Lee SK, Hwang SK, Han M, Eom JS, Kang HG, Han Y, Choi SB, Cho MH, Bhoo SH, An G, Hahn TR, Okita TW, Jeon JS.
Plant Mol. Biol. 2007  65(4)  531-46.
Identification of the ADP-glucose pyrophosphorylase isoforms essential for starch synthesis in the leaf and seed endosperm of rice (Oryza sativa L.).
Sikka,V.K., Choi,S.-B., Kavakli,I.H., Sakulsingharoj,C., Gupta,S., Ito,H. and Okita,T.W.
Plant Sci. 2001  161(3)  461-468
Subcellular compartmentation and allosteric regulation of the rice endosperm ADPglucose pyrophosphorylase
Chen,M., SanMiguel,P., A.C., Woo,S.S., Zhang,H., Wing,R.A. and Bennetzen,J.L.
Proc. Natl. Acad. Sci. U.S.A. 1997  94(7)  3431-3435
Microcolinearity in sh2-homologous regions of the maize, rice, and sorghum genomes.
Chen,M. and Bennetzen,J.L.
Plant Mol. Biol. 1996  32(6)  999-1001
Sequence composition and organization in the Sh2/A1-homologous region of rice.
Kavakli,H.I., Wu,Y. and Okita,T.W.
Plant Physiol. 1996  112  1399
DNA Sequence of a Near-Full Length cDNA Encoding the ADPglucose Pyrophosphorylase Large Subunit from Rice (Oryza sativa L) Endosperm (Accession No: U66041)(PGR96-116)
TextPresso Search Search textpresso for AGPL2 ( Recent references may be retrievable, but without any warranty )
DB Reference
Gramene ID GR:0101320
Gene Ontology response to inorganic substance( GO:0010035 )
response to desiccation( GO:0009269 )
glycogen biosynthetic process( GO:0005978 )
glucose-1-phosphate adenylyltransferase activity( GO:0008878 )
biosynthetic process( GO:0009058 )
cytosol( GO:0005829 )
plastid( GO:0009536 )
nucleotidyltransferase activity( GO:0016779 )
starch biosynthetic process( GO:0019252 )
seed maturation( GO:0010431 )
regulation of starch biosynthetic process( GO:0010581 )
response to salt stress( GO:0009651 )
seed development( GO:0048316 )
Trait Ontology starch content( TO:0000696 )
shrunken endosperm( TO:0000100 )
floury endosperm( TO:0000104 )
seed maturation( TO:0002661 )
grain weight( TO:0000590 )
grain yield( TO:0000396 )
seed quality( TO:0000162 )
salt tolerance( TO:0006001 )
seed development trait( TO:0000653 )
drought related trait( TO:0000394 )
1000-seed weight( TO:0000382 )
nutrient sensitivity( TO:0000480 )
Plant Ontology endosperm( PO:0009089 )
seed maturation stage( PO:0007632 )
fruit( PO:0009001 )
seed development stage( PO:0001170 )
seed imbibition stage( PO:0007022 )
seed( PO:0009010 )
Related Strains
Phenotype images
Last updated
Aug 31, 2023