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Detail of Gene

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Basic Information
CGSNL Gene Symbol WRKY45
Gene Symbol Synonym OsWRKY45
Gene Name Synonym Rice WRKY gene45
Allele OsWRKY45-1, OsWRKY45-2
Chromosome No. 5
Explanation BK005048. DQ298181. AY870611. WRKY71 in Zhang and Wang (2005) and in Berri et al. (2009). WRKY50 in Wu et al. (2005) and Sun et al. 2014. GQ331930, GQ331931, GQ331932 (OsWRKY45-1), GQ331927, GQ331928, GQ331929 (OsWRKY45-2). GO:1902065: response to L-glutamate.
Trait Class Seed - Morphological traits - Grain shape
Tolerance and resistance - Disease resistance
Tolerance and resistance - Insect resistance
Tolerance and resistance - Stress tolerance
cDNA Accession No. AK066255
MSU ID LOC_Os05g25770.1
RAP ID Os05g0322900
Links Oryzabase Chromosome View ( IRGSP 1.0 / Build5 )
RAP-DB ( IRGSP 1.0 / Build5 )
Related IDs List ( IRGSP 1.0 / Build5 )
INSD Accession List
(Test version)
Link to INSD Accession List
Link map Classical linkage map
Yao Y., Zhou J., Cheng C., Niu F., Zhang A., Sun B., Tu R., Wan J., Li Y., Huang Y., Xie K., Dai Y., Zhang H., Hong J.H., Pan X., Zhu J., Zhou H., Liu Z., Cao L., Chu H.
Plant Cell Environ. 2022  45(2)  542-555
A conserved clathrin-coated vesicle component, OsSCYL2, regulates plant innate immunity in rice.
An L., Zhang S., Guo P., Song L., Xie C., Guo H., Fang R., Jia Y.
Mol. Plant Pathol. 2022  23(1)  92-103
RIR1 represses plant immunity by interacting with mitochondrial complex I subunit in rice.
Li Y., Ting-Ting Li, Xiao-Rong He, Zhu Y., Feng Q., Xue-Mei Yang, Xin-Hui Zhou, Guo-Bang Li, Yun-Peng Ji, Jing-Hao Zhao, Zhi-Xue Zhao, Pu M., Shi-Xin Zhou, Ji-Wei Zhang, Yan-Yan Huang, Fan J., Wen-Ming Wang
Plant Biotechnol. J. 2021   
Blocking Osa-miR1871 enhances rice resistance against Magnaporthe oryzae and yield.
Yuan X., Wang H., Bi Y., Yan Y., Gao Y., Xiong X., Wang J., Li D., Song F.
Front Plant Sci 2021  12  749186
ONAC066, A Stress-Responsive NAC Transcription Activator, Positively Contributes to Rice Immunity Against <i>Magnaprothe oryzae</i> Through Modulating Expression of <i>OsWRKY62</i> and Three Cytochrome P450 Genes.
Qiu T., Zhao X., Feng H., Qi L., Yang J., You-Liang Peng, Zhao W.
Plant Biotechnol. J. 2021  19(11)  2277-2290
OsNBL3, a mitochondrion-localized pentatricopeptide repeat protein, is involved in splicing nad5 intron 4 and its disruption causes lesion mimic phenotype with enhanced resistance to biotic and abiotic stresses.
Zhang H., Wu T., Li Z., Huang K., Kim N.E., Ma Z., Kwon S.W., Jiang W., Du X.
Rice (N Y) 2021  14(1)  42
OsGATA16, a GATA transcription factor, Confers cold tolerance by Repressing OsWRKY45-1 at the Seedling Stage in Rice.
Jiang J., Yang G., Xin Y., Wang Z., Yan W., Chen Z., Tang X., Xia J.
Genes (Basel) 2021  12(5) 
Overexpression of <i>OsMed16</i> Inhibits the Growth of Rice and Causes Spontaneous Cell Death.
Hu B., Zhou Y., Zhou Z., Sun B., Zhou F., Yin C., Ma W., Chen H., Lin Y.
Plant Biotechnol. J. 2021   
Repressed OsMESL expression triggers reactive oxygen species-mediated broad-spectrum disease resistance in rice.
Zhao X., Zhang T., Feng H., Qiu T., Li Z., Yang J., Peng Y.L., Zhao W.
Rice (N Y) 2021  14(1)  10
OsNBL1, a Multi-Organelle Localized Protein, Plays Essential Roles in Rice Senescence, disease resistance, and salt tolerance.
Zhang H., Zheng D., Yin L., Song F., Jiang M.
Front Plant Sci 2021  12  652453
Functional Analysis of <i>OsMED16</i> and <i>OsMED25</i> in Response to Biotic and Abiotic Stresses in Rice.
Liu X., Song L., Zhang H., Lin Y., Shen X., Guo J., Su M., Shi G., Wang Z., Lu G.D.
Mol. Plant Pathol. 2021  22(12)  1613-1623
Rice ubiquitin-conjugating enzyme OsUBC26 is essential for immunity to the blast fungus Magnaporthe oryzae.
Gong P., Luo Y., Huang F., Chen Y., Zhao C., Wu X., Li K., Yang X., Cheng F., Xiang X., Wu C., Pan G.
Plant Mol. Biol. 2019  100(1-2)  133-149
Disruption of a Upf1-like helicase-encoding gene OsPLS2 triggers light-dependent premature leaf senescence in rice.
Sánchez-Sanuy F., Peris-Peris C., Tomiyama S., Okada K., Hsing Y.I., San Segundo B., Campo S.
BMC Plant Biol. 2019  19(1)  563
Osa-miR7695 enhances transcriptional priming in defense responses against the rice blast fungus.
Hoang T.V., Vo K.T.X., Rahman M.M., Choi S.H., Jeon J.S.
Plant Sci. 2019  289  110273
Heat stress transcription factor OsSPL7 plays a critical role in reactive oxygen species balance and stress responses in rice.
Atul Prakash Sathe, Su X., Chen Z., Chen T., Wei X., Tang S., Xiao-Bo Zhang, Jian-Li Wu
Rice (N Y) 2019  12(1)  68
Identification and characterization of a spotted-leaf mutant spl40 with enhanced bacterial blight resistance in rice.
Liu M., Shi Z., Zhang X., Wang M., Zhang L., Zheng K., Liu J., Hu X., Di C., Qian Q., He Z., Yang D.L.
Nat Plants 2019  5(4)  389-400
Inducible overexpression of Ideal Plant Architecture1 improves both yield and disease resistance in rice.
Ke Y., Kang Y., Wu M., Liu H., Hui S., Zhang Q., Li X., Xiao J., Wang S.
Rice (N Y) 2019  12(1)  25
Jasmonic Acid-Involved OsEDS1 Signaling in Rice-Bacteria Interactions.
Cheng X., Zhao Y., Jiang Q., Yang J., Zhao W., Taylor I.A., Peng Y.L., Wang D., Liu J.
Nucleic Acids Res. 2019  47(8)  4308-4318
Structural basis of dimerization and dual W-box DNA recognition by rice WRKY domain.
Uji Y., Kashihara K., Kiyama H., Mochizuki S., Akimitsu K., Gomi K.
Int J Mol Sci 2019  20(12) 
Jasmonic Acid-Induced VQ-Motif-Containing Protein OsVQ13 Influences the OsWRKY45 Signaling Pathway and grain size by Associating with OsMPK6 in Rice.
Hong Y., Liu Q., Cao Y., Zhang Y., Chen D., Lou X., Cheng S., Cao L.
Front Plant Sci 2019  10  752
The <i>OsMPK15</i> Negatively Regulates <i>Magnaporthe oryza</i> and <i>Xoo</i> disease resistance via SA and JA Signaling Pathway in Rice.
Han Y., Song L., Peng C., Liu X., Liu L., Zhang Y., Wang W., Zhou J., Wang S., Ebbole D., Wang Z., Lu G.D.
Plant Physiol. 2019  179(4)  1416-1430
A <i>Magnaporthe</i> Chitinase Interacts with a Rice Jacalin-Related Lectin to Promote Host Colonization.
Xu X., Chen Z., Shi Y.F., Wang H.M., He Y., Shi L., Chen T., Wu J.L., Zhang X.B.
BMC Plant Biol. 2018  18(1)  264
Functional inactivation of OsGCNT induces enhanced disease resistance to Xanthomonas oryzae pv. oryzae in rice.
Kusajima M., Shima S., Fujita M., Minamisawa K., Che F.S., Yamakawa H., Nakashita H.
Biosci. Biotechnol. Biochem. 2018  82(9)  1522-1526
Involvement of ethylene signaling in Azospirillum sp. B510-induced disease resistance in rice.
Chen Z., Chen T., Sathe A.P., He Y., Zhang X.B., Wu J.L.
Int J Mol Sci 2018  19(12) 
Identification of a Novel Semi-Dominant Spotted-Leaf Mutant with Enhanced Resistance to <i>Xanthomonas</i><i>oryzae</i> pv. <i>oryzae</i> in Rice.
Wang J., Zhou L., Shi H., Chern M., Yu H., Yi H., He M., Yin J., Zhu X., Li Y., Li W., Liu J., Wang J., Chen X., Qing H., Wang Y., Liu G., Wang W., Li P., Wu X., Zhu L., Zhou J.M., Ronald P.C., Li S., Li J., Chen X.
Science 2018  361(6406)  1026-1028
A single transcription factor promotes both yield and immunity in rice.
Liu Y., Cao Y., Zhang Q., Li X., Wang S.
Plant Physiol. 2018  178(2)  923-935
A Cytosolic Triosephosphate Isomerase Is a Key Component in Xa3/XA26-Mediated Resistance.
Filipe O., De Vleesschauwer D., Haeck A., Demeestere K., Höfte M.
Sci Rep 2018  8(1)  3864
The energy sensor OsSnRK1a confers broad-spectrum disease resistance in rice.
Hu L., Ye M., Kuai P., Ye M., Erb M., Lou Y.
New Phytol. 2018  219(3)  1097-1111
OsLRR-RLK1, an early responsive leucine-rich repeat receptor-like kinase, initiates rice defense responses against a chewing herbivore.
Liu Q., Ning Y., Zhang Y., Yu N., Zhao C., Zhan X., Wu W., Chen D., Wei X., Wang G.L., Cheng S., Cao L.
Plant Cell 2017  29(2)  345-359
OsCUL3a Negatively Regulates Cell Death and Immunity by Degrading OsNPR1 in Rice.
Wang J., Islam F., Li L., Long M., Yang C., Jin X., Ali B., Mao B., Zhou W.
Int J Mol Sci 2017  18(9) 
Complementary RNA-Sequencing Based Transcriptomics and iTRAQ Proteomics Reveal the Mechanism of the Alleviation of Quinclorac Stress by Salicylic Acid in Oryza sativa ssp. japonica.
Choi N.Y., Lee E., Lee S.G., Choi C.H., Park S.R., Ahn I., Bae S.C., Hwang C.H., Hwang D.J.
Front Plant Sci 2017  8  1628
Genome-Wide Expression Profiling of OsWRKY Superfamily Genes during Infection with Xanthomonas oryzae pv. oryzae Using Real-Time PCR.
Takatsuji H.
Front Plant Sci 2017  8  171
Regulating Tradeoffs to Improve Rice Production.
Zhong X., Yang J., Shi Y., Wang X., Wang G.L.
Mol. Plant Pathol. 2017   
The DnaJ protein OsDjA6 negatively regulates rice innate immunity to the blast fungus Magnaporthe oryzae.
Fukushima S., Mori M., Sugano S., Takatsuji H.
Plant Cell Physiol. 2016  57(12)  2541-2551
Transcription Factor WRKY62 Plays a Role in Pathogen Defense and Hypoxia-Responsive Gene Expression in Rice.
Kadotani N., Akagi A., Takatsuji H., Miwa T., Igarashi D.
BMC Plant Biol. 2016  16(1)  60
Exogenous proteinogenic amino acids induce systemic resistance in rice.
Huang W.K., Ji H.L., Gheysen G., Kyndt T.
Mol. Plant Pathol. 2016  17(4)  614-24
Thiamine-induced priming against root-knot nematode infection in rice involves lignification and hydrogen peroxide generation.
Liu H., Dong S., Sun D., Liu W., Gu F., Liu Y., Guo T., Wang H., Wang J., Chen Z.
PLoS ONE 2016  11(11)  e0166249
CONSTANS-Like 9 (OsCOL9) Interacts with Receptor for Activated C-Kinase 1(OsRACK1) to Regulate Blast Resistance through Salicylic Acid and Ethylene Signaling Pathways.
Li S.B., Xu S.R., Zhang R.N., Liu Y., Zhou R.C.
J. Microbiol. Biotechnol. 2015   
The antibiosis action and rice induced resistance, mediated by a lipopeptide from Bacillus amyloliquefaciens B014, in controlling rice disease caused by Xanthomonas oryzae pv. Oryzae.
Ueda Y., Siddique S., Frei M.
Plant Physiol. 2015   
A novel gene OsORAP1 enhances cell death in ozone stress in rice (Oryza sativa L.).
Ueno Y., Yoshida R., Kishi-Kaboshi M., Matsushita A., Jiang C.J., Goto S., Takahashi A., Hirochika H., Takatsuji H.
PLoS Pathog. 2015  11(10)  e1005231
Abiotic Stresses Antagonize the Rice Defence Pathway through the Tyrosine-Dephosphorylation of OsMPK6.
Sun L.J.a, Huang L.b, Li D.Y.b, Zhang H.J.b, Song F.M.b
Zhiwu Shengli Xuebao/Plant Physiology Journal 2014  50  1651-1658
Comprehensive expression analysis suggests overlapping of rice OsWRKY transcription factor genes during abiotic stress responses
Goto S., Sasakura-Shimoda F., Suetsugu M., Selvaraj M.G., Hayashi N., Yamazaki M., Ishitani M., Shimono M., Sugano S., Matsushita A., Tanabata T., Takatsuji H.
Plant Biotechnol. J. 2014   
Development of disease-resistant rice by optimized expression of WRKY45.
Su Z.Z., Mao L.J., Li N., Feng X.X., Yuan Z.L., Wang L.W., Lin F.C., Zhang C.L.
PLoS ONE 2013  8(4)  e61332
Evidence for Biotrophic Lifestyle and Biocontrol Potential of Dark Septate Endophyte Harpophora oryzae to Rice blast disease.
Xu J., Audenaert K., Hofte M., De Vleesschauwer D.
PLoS ONE 2013  8(6)  e67413
Abscisic Acid Promotes Susceptibility to the Rice Leaf Blight Pathogen Xanthomonas oryzae pv oryzae by Suppressing Salicylic Acid-Mediated Defenses.
Geng S., Li A., Tang L., Yin L., Wu L., Lei C., Guo X., Zhang X., Jiang G., Zhai W., Wei Y., Zheng Y., Lan X., Mao L.
J. Exp. Bot. 2013  64(11)  3125-36
TaCPK2-A, a calcium-dependent protein kinase gene that is required for wheat powdery mildew resistance enhances bacterial blight resistance in transgenic rice.
Yang D.L., Yang Y., He Z.
Mol Plant 2013  6(3)  675-85
Role of plant hormones and their cross-talks in rice immunity.
Jiang C.J., Shimono M., Sugano S., Kojima M., Liu X., Inoue H., Sakakibara H., Takatsuji H.
Mol. Plant Microbe Interact. 2013  26(3)  287-96
Cytokinins act synergistically with salicylic acid to activate defense gene expression in rice.
Inoue H., Hayashi N., Matsushita A., Xinqiong L., Nakayama A., Sugano S., Jiang C.J., Takatsuji H.
Proc. Natl. Acad. Sci. U.S.A. 2013  110(23)  9577-82
Blast resistance of CC-NB-LRR protein Pb1 is mediated by WRKY45 through protein-protein interaction.
Nakayama A., Fukushima S., Goto S., Matsushita A., Shimono M., Sugano S., Jiang C.J., Akagi A., Yamazaki M., Inoue H., Takatsuji H.
BMC Plant Biol. 2013  13  150
Genome-wide identification of WRKY45-regulated genes that mediate benzothiadiazole-induced defense responses in rice.
Todaka D., Nakashima K., Shinozaki K., Kazuko Yamaguchi-Shinozaki
Rice (N Y) 2012  5  6
Toward understanding transcriptional regulatory networks in abiotic stress responses and tolerance in rice.
Rice WRKY Working Group
Rice (N Y) 2012  5  3
Nomenclature report on rice WRKYs. -Conflict regarding gene names and its solution
Shimono M., Koga H., Akagi A., Hayashi N., Goto S., Sawada M., Kurihara T., Matsushita A., Sugano S., Jiang C.J., Kaku H., Inoue H., Takatsuji H.
Mol. Plant Pathol. 2012  13(1)  83-94
Rice WRKY45 plays important roles in fungal and bacterial disease resistance.
Matsushita A., Inoue H., Goto S., Nakayama A., Sugano S., Hayashi N., Takatsuji H.
Plant J. 2012   
The nuclear ubiquitin proteasome degradation affects WRKY45 function in the rice defense program.
Tao Z., Kou Y., Liu H., Li X., Xiao J., Wang S.
J. Exp. Bot. 2011  62(14)  4863-74
OsWRKY45 alleles play different roles in abscisic acid signalling and salt stress tolerance but similar roles in drought and cold tolerance in rice.
Chang-Jie Jiang, Shimono M., Sugano S., Kojima M., Yazawa K., Yoshida R., Inoue H., Hayashi N., Sakakibara H., Takatsuji H.
Mol. Plant Microbe Interact. 2010  23(6)  791-8
Abscisic acid interacts antagonistically with salicylic acid signaling pathway in rice-Magnaporthe grisea interaction.
Tao Z,Liu H,Qiu D,Zhou Y,Li X,Xu C,Wang S
Plant Physiol. 2009  151(2)  936-48
A pair of allelic WRKY genes play opposite roles in rice-bacteria interactions.
Chang-Jie Jiang, Shimono M., Maeda S., Inoue H., Mori M., Hasegawa M., Sugano S., Takatsuji H.
Mol. Plant Microbe Interact. 2009  22(7)  820-9
Suppression of the rice fatty-acid desaturase gene OsSSI2 enhances resistance to blast and leaf blight diseases in rice.
Yasuda M., Isawa T., Shinozaki S., Minamisawa K., Nakashita H.
Biosci. Biotechnol. Biochem. 2009  73(12)  2595-9
Effects of colonization of a bacterial endophyte, Azospirillum sp. B510, on disease resistance in rice.
Berri S,Abbruscato P,Faivre-Rampant O,Brasileiro AC,Fumasoni I,Satoh K,Kikuchi S,Mizzi L,Morandini P,Pe ME,Piffanelli P
BMC Plant Biol 2009  9  120
Characterization of WRKY co-regulatory networks in rice and Arabidopsis.
Shimono M,Sugano S,Nakayama A,Jiang CJ,Ono K,Toki S,Takatsuji H
Plant Cell 2007  19  2064-76
Rice WRKY45 plays a crucial role in benzothiadiazole-inducible blast resistance.
Christian A. Ross Yue Liu Qingxi J. Shen
Journal of integrative plant biology 2007  49(6)  827-842
The WRKY Gene Family in Rice (Oryza sativa)
Ryu,H.S., Han,M., Lee,S.K., Cho,J.I., Ryoo,N., Heu,S., Lee,Y.H., Bhoo,S.H., Wang,G.L., Hahn,T.R. and Jeon,J.S.
Plant Cell Rep. 2006  25(8)  836-847
A comprehensive expression analysis of the WRKY gene superfamily in rice plants during defense response.
Zhang Y., Wang L.
BMC evolutionary biology 2005  5  1
The WRKY transcription factor superfamily: its origin in eukaryotes and expansion in plants.
Kun-Lu Wu, Ze-Jian Guo, Hai-Hua Wang, Li J.
DNA research : an international journal for rapid publication of reports on genes and genomes 2005  12(1)  9-26
The WRKY family of transcription factors in rice and Arabidopsis and their origins.
Xie Z, Zhang ZL, Zou X, Huang J, Ruas P, Thompson D, Shen QJ.
Plant Physiol. 2005  137 (1)  176-189
Annotations and Functional Analyses of the Rice WRKY Gene Superfamily Reveal Positive and Negative Regulators of Abscisic Acid Signaling in Aleurone Cells
Zhang,Z.L., Xie,Z., Zou,X., Casaretto,J., Ho,T.H. and Shen,Q.J.
Plant Physiol. 2004  134 (4)  1500-1513
A Rice WRKY Gene Encodes a Transcriptional Repressor of the Gibberellin Signaling Pathway in Aleurone Cells
Qiu,Y., Jing,S., Fu,J., Li,L. and Yu,D.
Chin. Sci. Bull. 2004  49  2159-2168
Cloning and analysis of expression profile of 13 WRKY genes in rice
TextPresso Search Search textpresso for WRKY45 ( Recent references may be retrievable, but without any warranty )
DB Reference
Gramene ID -
Gene Ontology defense response( GO:0006952 )
sequence-specific DNA binding( GO:0043565 )
salicylic acid mediated signaling pathway( GO:0009863 )
response to molecule of bacterial origin( GO:0002237 )
response to salt stress( GO:0009651 )
lignin biosynthetic process( GO:0009809 )
response to cold( GO:0009409 )
transcription factor activity( GO:0003700 )
response to abscisic acid stimulus( GO:0009737 )
response to salicylic acid stimulus( GO:0009751 )
response to vitamin B1( GO:0010266 )
defense response to bacterium( GO:0042742 )
defense response to fungus( GO:0050832 )
defense response to insect( GO:0002213 )
response to herbivore( GO:0080027 )
Trait Ontology blast disease( TO:0000074 )
abscisic acid sensitivity( TO:0000615 )
salt tolerance( TO:0006001 )
cold tolerance( TO:0000303 )
plant growth hormone sensitivity( TO:0000401 )
stem borer resistance( TO:0000454 )
bacterial blight disease resistance( TO:0000175 )
grain size( TO:0000397 )
disease resistance( TO:0000112 )
salt sensitivity( TO:0000429 )
Plant Ontology -
Related Strains
Phenotype images
Last updated
May 16, 2022