Gene - Detail

Detail of Gene

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Basic Information
CGSNL Gene Symbol NRAMP1
Gene Symbol Synonym OsNramp1, OsNRAMP1, OsNramp6
Gene Name Synonym homologues of mammalian Nramp1 gene
Protein Name
Chromosome No. 7
Explanation L41217, S81897. D15268. integral membrane protein. Q0D7E4. TO:0006059: cadmium concentration. TO:0006049: iron concentration. TO:0006053: zinc concentration. TO:0006054: arsenic concentration. OsNramp6 in Liang et al. 2014. arsenic transport. NRAMP transporter (Fe/Mn/Cd/As transport).
Trait Class Tolerance and resistance - Stress tolerance
cDNA Accession No. AK121534
MSU ID LOC_Os07g15460.1
RAP ID Os07g0258400
Links Oryzabase Chromosome View ( IRGSP 1.0 / Build5 )
RAP-DB ( IRGSP 1.0 / Build5 )
Related IDs List ( IRGSP 1.0 / Build5 )
INSD Accession List
(Test version)
Link to INSD Accession List
Link map Classical linkage map
Liang G., Zhang H., Li Y., Pu M., Yang Y., Li C., Lu C., Xu P., Yu D.
J Integr Plant Biol 2020  62(5)  668-689
Oryza sativa FER-LIKE FE DEFICIENCY-INDUCED TRANSCRIPTION FACTOR (OsFIT/OsbHLH156) interacts with OsIRO2 to regulate iron homeostasis.
Sánchez-Sanuy F., Peris-Peris C., Tomiyama S., Okada K., Hsing Y.I., San Segundo B., Campo S.
BMC Plant Biol. 2019  19(1)  563
Osa-miR7695 enhances transcriptional priming in defense responses against the rice blast fungus.
Cao Z.Z., Lin X.Y., Yang Y.J., Guan M.Y., Xu P., Chen M.X.
BMC Plant Biol. 2019  19(1)  250
Gene identification and transcriptome analysis of low cadmium accumulation rice mutant (lcd1) in response to cadmium stress using MutMap and RNA-seq.
Mani A., Sankaranarayanan K.
Protein J. 2018  37(3)  237-247
In Silico Analysis of Natural Resistance-Associated Macrophage Protein (NRAMP) Family of Transporters in Rice.
Tanaka N., Uraguchi S., Kajikawa M., Saito A., Ohmori Y., Fujiwara T.
Plant J. 2018  96(5)  997-1006
A rice PHD-finger protein OsTITANIA, is a growth regulator that functions through elevating expression of transporter genes for multiple metals.
Chen X., Ouyang Y., Fan Y., Qiu B., Zhang G., Zeng F.
J. Exp. Bot. 2018  69(21)  5279-5291
The pathway of transmembrane cadmium influx via calcium-permeable channels and its spatial characteristics along rice root.
Chen Y., Han Y.H., Cao Y., Zhu Y.G., Rathinasabapathi B., Ma L.Q.
Front Plant Sci 2017  8  268
Arsenic Transport in Rice and Biological Solutions to Reduce Arsenic Risk from Rice.
Bashir K., Ishimaru Y., Itai R.N., Senoura T., Takahashi M., An G., Oikawa T., Ueda M., Sato A., Uozumi N., Nakanishi H., Nishizawa N.K.
Plant Mol. Biol. 2015  88(1-2)  165-76
Iron deficiency regulated OsOPT7 is essential for iron homeostasis in rice.
Tiwari M., Sharma D., Dwivedi S., Singh M., Tripathi R.D., Trivedi P.K.
Plant Cell Environ. 2014  37(1)  140-52
Expression in Arabidopsis and cellular localization reveal involvement of rice NRAMP, OsNRAMP1, in arsenic transport and tolerance.
Liang C., Wang Y., Zhu Y., Tang J., Hu B., Liu L., Ou S., Wu H., Sun X., Chu J., Chu C.
Proc. Natl. Acad. Sci. U.S.A. 2014  111(27)  10013-8
OsNAP connects abscisic acid and leaf senescence by fine-tuning abscisic acid biosynthesis and directly targeting senescence-associated genes in rice.
Agarwal S., Tripura Venkata VG., Kotla A., Mangrauthia S.K., Neelamraju S.
Gene 2014  546(2)  430-6
Expression patterns of QTL based and other candidate genes in Madhukar × Swarna RILs with contrasting levels of iron and zinc in unpolished rice grains.
Takahashi R., Ishimaru Y., Shimo H., Bashir K., Senoura T., Sugimoto K., Ono K., Suzui N., Kawachi N., Ishii S., Yin Y.G., Fujimaki S., Yano M., Nishizawa N.K., Nakanishi H.
PLoS ONE 2014  9(6)  e98816
From laboratory to field: OsNRAMP5-knockdown rice is a promising candidate for Cd phytoremediation in paddy fields.
Kobayashi T.a b, Nakanishi Itai R.c, Nishizawa N.K.b
Rice 2014  7 
Iron deficiency responses in rice roots
Jan A., Maruyama K., Todaka D., Kidokoro S., Abo M., Yoshimura E., Shinozaki K., Nakashima K., Kazuko Yamaguchi-Shinozaki
Plant Physiol. 2013  161(3)  1202-16
OsTZF1, a CCCH-tandem zinc finger protein, confers delayed senescence and stress tolerance in rice by regulating stress-related genes.
Ishikawa S., Ishimaru Y., Igura M., Kuramata M., Abe T., Senoura T., Hase Y., Arao T., Nishizawa N.K., Nakanishi H.
Proc. Natl. Acad. Sci. U.S.A. 2012  109(47)  19166-71
Ion-beam irradiation, gene identification, and marker-assisted breeding in the development of low-cadmium rice.
Wang L., Ying Y., Narsai R., Ye L., Zheng L., Tian J., Whelan J., Shou H.
Plant Cell Environ. 2012  36(1)  224-36.
Identification of OsbHLH133 as a regulator of iron distribution between roots and shoots in Oryza sativa.
Anuradha K., Agarwal S., Rao Y.V., Rao K.V., Viraktamath B.C., Sarla N.
Gene 2012  508(2)  233-40
Mapping QTLs and candidate genes for iron and zinc concentrations in unpolished rice of Madhukar×Swarna RILs.
Takanashi H., Ishimaru Y., Bashir K., Fujimoto M., Shimo H., An G., Nagasaka S., Nishizawa N.K., Nakanishi H., Tsutsumi N.
Nature Communications 2011  2  322
The rice mitochondrial iron transporter is essential for plant growth
Takahashi R. , Ishimaru Y. , Senoura T. , Shimo H. , Ishikawa S. , Arao T. , Nakanishi H. , Nishizawa N.K.
J. Exp. Bot. 2011    -
The OsNRAMP1 iron transporter is involved in Cd accumulation in rice.
Takahashi R., Ishimaru Y., Nakanishi H., Nishizawa N.K.
Plant Signal Behav 2011  6(11) 
Role of the iron transporter OsNRAMP1 in cadmium uptake and accumulation in rice.
Ishimaru Y., Masuda H., Bashir K., Inoue H., Tsukamoto T., Takahashi M., Nakanishi H., Aoki N., Hirose T., Ohsugi R., Naoko K Nishizawa
Plant J. 2010  62(3)  379-90
Rice metal-nicotianamine transporter, OsYSL2, is required for the long-distance transport of iron and manganese.
Narayanan NN, Vasconcelos MW, Grusak MA.
Plant Physiol. Biochem. 2007  45(5)  277-86.
Expression profiling of Oryza sativa metal homeostasis genes in different rice cultivars using a cDNA macroarray.
C Curie, J M Alonso, M Le Jean, J R Ecker, J F Briat
Biochem. J. 2000  347 Pt 3  749-55
Involvement of NRAMP1 from Arabidopsis thaliana in iron transport.
Belouchi,A., Kwan,T. and Gros,P.
Plant Mol. Biol. 1997  33(6)  1085-1092
Cloning and characterization of the OsNramp family from Oryza sativa, a new family of membrane proteins possibly implicated in the transport of metal ions.
Belouchi,A., Cellier,M., Kwan,T., Saini,H.S., Leroux,G. and Gros,P.
Plant Mol. Biol. 1995  29(6)  1181-1196
The macrophage-specific membrane protein Nramp controlling natural resistance to infections in mice has homologues expressed in the root system of plants.
TextPresso Search Search textpresso for NRAMP1 ( Recent references may be retrievable, but without any warranty )
DB Reference
Gramene ID -
Gene Ontology iron ion transmembrane transporter activity( GO:0005381 )
cadmium ion transport( GO:0015691 )
integral to membrane( GO:0016021 )
metal ion transport( GO:0030001 )
iron ion homeostasis( GO:0055072 )
response to arsenic( GO:0046685 )
response to cadmium ion( GO:0046686 )
Trait Ontology -
Plant Ontology endodermis( PO:0000252 )
pericycle( PO:0006203 )
root( PO:0009005 )
Related Strains
Phenotype images
Last updated
Sep 17, 2020