Gene - Detail

Detail of Gene

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Basic Information
CGSNL Gene Symbol SPL11
Gene Symbol Synonym spl11, spl11*, OsPUB11, PUB11, OsPUB11/SPL11, PUB11/SPL11
Gene Name Synonym spotted leaf11, spotted leaf-11, Protein spotted leaf 11, Cell death-related protein SPL11, plant U-box-containing protein 11, U-box protein 11, U-box-type E3 ubiquitin ligase 11
Allele spl11
Chromosome No. 12
Explanation Rust colored spots which start appearing at maximum tillering stage and continue until maturity. The spots are distributed throughout the leaf blade with maximum concentration along the midrib. EC=6.3.2.- A2ZLU6(indica). Q0IMG9(japonica). PO:0009025; leaf. GRO:0007048; 04-stem elongation stage ; GRO:0007148; 05-booting stage ; GRO:0007049; 03-tillering stage ; GRO:0007044; 06-heading stage ; GRO:0007042; 08-dough stage ; GRO:0007045; 09-mature grain stage ; GRO:0007046; 07-milk stage. AY652589, AY652590. a U-Box/Armadillo Repeat Protein. LOC_Os12g38210. class II PUB protein (U-box + ARM/HEAT). EST: CB680406, BF430451, CF305067, AT003699, AT003719, AA749599, AU173870, AU197209, BI812454. KC611075-KC611087 (O. sativa and wild rice species, partial cds). U-box domain and ARM repeat domain protein.
Trait Class Reproductive organ - Heading date
Tolerance and resistance - Lesion mimic
Tolerance and resistance - Disease resistance
cDNA Accession No. AK105835
MSU ID LOC_Os12g38210.1
RAP ID Os12g0570000
Links Oryzabase Chromosome View ( IRGSP 1.0 / Build5 )
RAP-DB ( IRGSP 1.0 / Build5 )
Related IDs List ( IRGSP 1.0 / Build5 )
INSD Accession List
(Test version)
Link to INSD Accession List
Link map Classical linkage map
Wang R., You X., Zhang C., Fang H., Wang M., Zhang F., Kang H., Xu X., Liu Z., Wang J., Zhao Q., Wang X., Hao Z., He F., Tao H., Wang D., Wang J., Fang L., Qin M., Zhao T., Zhang P., Xing H., Xiao Y., Liu W., Xie Q., Wang G.L., Ning Y.
Genome Biol. 2022  23(1)  154
An ORFeome of rice E3 ubiquitin ligases for global analysis of the ubiquitination interactome.
Zhang A., Jiang H., Chu H., Cao L., Chen J.
Curr Issues Mol Biol 2022  44(5)  2350-2361
Rice lesion mimic Gene Cloning and Association Analysis for disease resistance.
Kim M.S., Kang K.K., Cho Y.G.
Int J Mol Sci 2021  22(21) 
Molecular and Functional Analysis of U-box E3 Ubiquitin Ligase Gene Family in Rice (<i>Oryza</i><i>sativa</i>).
Fan J., Bai P., Ning Y., Wang J., Shi X., Xiong Y., Zhang K., He F., Zhang C., Wang R., Meng X., Zhou J., Wang M., Shirsekar G., Park C.H., Bellizzi M., Liu W., Jeon J.S., Xia Y., Shan L., Wang G.L.
Cell Host Microbe 2018  23(4)  498-510.e5
The Monocot-Specific Receptor-like Kinase SDS2 Controls Cell Death and Immunity in Rice.

PLoS Pathog. 2015  11(4)  e1004807
Correction: The RhoGAP SPIN6 Associates with SPL11 and OsRac1 and Negatively Regulates Programmed Cell Death and Innate Immunity in Rice.
Liu J., Park C.H., He F., Nagano M., Wang M., Bellizzi M., Zhang K., Zeng X., Liu W., Ning Y., Kawano Y., Wang G.L.
PLoS Pathog. 2015  11(2)  e1004629
The RhoGAP Spin6 associates with SPL11 and OsRac1 and negatively regulates programmed cell death and innate immunity in rice.
Zhang H., Liu J., He F., Wang Z., Ning Y., Wang G.L.
Plant Signal Behav 2015  10(8)  e1039212
OsHUB1 and OsHub2 interact with SPIN6 and form homo- and hetero-dimers in rice.
Zhu,T., Xu,P.Z., Liu,J.P., Peng,S., Mo,X.C. and Gao,L.Z.
Mol. Phylogenet. Evol. 2014  70  348-361
Phylogenetic relationships and genome divergence among the AA- genome species of the genus Oryza as revealed by 53 nuclear genes and 16 intergenic regions
Cai Y., Vega-Sánchez ME., Park C.H., Bellizzi M., Guo Z., Wang G.L.
PLoS ONE 2014  9(1)  e87258
RBS1, an RNA binding protein, interacts with Spin1 and is involved in flowering time control in rice.
Shirsekar G.S., Vega-Sánchez ME., Bordeos A., Baraoidan M., Swisshelm A., Fan J., Park C.H., Leung H., Wang G.L.
Mol. Plant Microbe Interact. 2014  27(6)  528-36
Identification and characterization of suppressor mutants of spl11- mediated cell death in rice.
Liu J., Li W., Ning Y., Shirsekar G., Wang X., Dai L., Wang Z., Liu W., Wang G.L.
Plant Physiol. 2012  160(1)  28-37
The U-box E3 ligase SPL11/PUB13 Is a Convergence Point of Defense and Flowering Signaling in Plants.
Li-Rong Zeng, Chan Ho Park, R C Venu, Gough J., Guo-Liang Wang
Mol Plant 2008  1(5)  800-15
Classification, expression pattern, and E3 ligase activity assay of rice U-box-containing proteins.
Vega-Sanchez ME,Zeng L,Chen S,Leung H,Wang GL
Plant Cell 2008  20  1456-69
SPIN1, a K homology domain protein negatively regulated and ubiquitinated by the E3 ubiquitin ligase SPL11, is involved in flowering time control in rice.
Kojo K, Yaeno T, Kusumi K, Matsumura H, Fujisawa S, Terauchi R, Iba K.
Plant Cell Physiol. 2006  47(8)  1035-44
Regulatory mechanisms of ROI generation are affected by rice spl mutations.
Jantasuriyarat C, Gowda M, Haller K, Hatfield J, Lu G, Stahlberg E, Zhou B, Li H, Kim H, Yu Y, Dean RA, Wing RA, Soderlund C, Wang GL.
Plant Physiol. 2005  138(1)  105-115
Large-scale identification of expressed sequence tags involved in rice and rice blast fungus interaction.
Zeng,L.R., Qu,S., Bordeos,A., Yang,C., Baraoidan,M., Yan,H., Xie,Q., Nahm,B.H., Leung,H. and Wang,G.L.
Plant Cell 2004  16(10)  2795-2808
Spotted leaf11, a Negative Regulator of Plant Cell Death and Defense, Encodes a U-Box/Armadillo Repeat Protein Endowed with E3 Ubiquitin Ligase Activity.
Zeng L, Yin Z, Chen J, Leung H, Wang GL.
Molecular Genetics & Genomics (Molecular General Genetics up to 2001) 2002  268(2)  253-261
Fine genetic mapping and physical delimitation of the lesion mimic gene Spl11 to a 160-kb DNA segment of the rice genome.
Z Yin, J Chen, L Zeng, M Goh, H Leung, G S Khush, G L Wang
Mol. Plant Microbe Interact. 2000  13(8)  869-76
Characterizing rice lesion mimic mutants and identifying a mutant with broad-spectrum resistance to rice blast and bacterial blight.
Singh, K., D.S. Multani and G.S. Khush
RGN 1995  12  192-193.
A new spotted leaf mutant in rice.
TextPresso Search Search textpresso for SPL11 ( Recent references may be retrievable, but without any warranty )
DB Reference
Gramene ID GR:0060912
Gene Ontology ubiquitin ligase complex( GO:0000151 )
binding( GO:0005488 )
protein ubiquitination( GO:0016567 )
modification-dependent protein catabolic process( GO:0019941 )
ubiquitin-protein ligase activity( GO:0004842 )
disease resistance( GO:0009614 )
negative regulation of apoptosis( GO:0043066 )
negative regulation of innate immune response( GO:0045824 )
negative regulation of long-day photoperiodism, flowering( GO:0048579 )
regulation of photoperiodism, flowering( GO:2000028 )
defense response to bacterium( GO:0042742 )
defense response to fungus( GO:0050832 )
regulation of programmed cell death( GO:0043067 )
regulation of defense response( GO:0031347 )
Trait Ontology mimic response( TO:0000063 )
variegated leaf( TO:0000069 )
disease resistance( TO:0000112 )
blast disease( TO:0000074 )
bacterial blight disease resistance( TO:0000175 )
Plant Ontology vascular leaf( PO:0009025 )
Related Strains
F Lines 5
Backcross Fn Generation (T65) 1
Phenotype images
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Photo from A. Yoshimura
Last updated
Feb 1, 2023