|
Basic Information
|
|
CGSNL Gene Symbol
|
YSL2
|
|
Gene Symbol Synonym
|
OsYSL2, Os-YSL2, OsYs6
|
|
CGSNL Gene Name
|
YELLOW STRIP-LIKE GENE 2
|
|
Gene Name Synonym
|
rice YSL (yellow stripe-like) gene2, Metal-nicotianamine transporter YSL2, Protein YELLOW STRIPE LIKE 2, ferrous Fe- and Mn-NA transporter OsYSL2, yellow stripe 1-like transporter 2
|
|
Protein Name
|
METAL-NICOTIANAMINE TRANSPORTER YSL2
|
|
Allele
|
|
|
Chromosome No.
|
2
|
|
Explanation
|
This gene encodes a rice metal-NA (nicotianamine) transporter that is responsible for the phloem transport of Fe and Mn and the translocation of Fe and Mn into the grain. yellow stripe 1-like. YS1-like metal-nicotianamine transporter. IRON(II)-NICOTIANAMINE ACID TRANSPORTER. Q6H3Z6. AB126253, AB164646. CI446246. D42870, BE228381, BE230357. TO:0006049: iron concentration. TO:0020089: iron content trait. TO:0006053: zinc concentration. Fe(III)-MAs (mugineic acid family phytosiderophores)/Fe(II)-NA (nicotianamine) transporter.
|
|
Trait Class
|
Biochemical character
Tolerance and resistance - Stress tolerance
|
|
Expression
|
|
|
Sequence/Locus
|
|
cDNA Accession No.
|
AB126253
|
|
MSU ID
|
LOC_Os02g43370.1
LOC_Os02g43370.2
|
|
RAP ID
|
Os02g0649900
|
|
Links
|
Oryzabase Chromosome View
(
IRGSP 1.0
/
Build5
)
RAP-DB
(
IRGSP 1.0
/
Build5
)
Related IDs List (
IRGSP 1.0
/
Build5
)
|
INSD Accession List
(Test version)
|
Link to INSD Accession List
|
|
Map
|
|
Locate(cM)
|
|
|
Link map
|
Classical linkage map
|
|
References
|
|
Lu W.C., Zheng X.L., Xiao Y.T., Sun Z.F., Tang Z., Zhao F.J., Huang X.Y.
Int J Mol Sci 2025 26(19)
Spatiotemporal Transcriptome Profiling Reveals Nutrient Transport Dynamics in Rice Nodes and Roots During Reproductive Development.
|
|
Kobayashi T., Maeda K., Suzuki Y., Nishizawa N.K.
Rice (N Y) 2022 15(1) 54
Simultaneous Enhancement of iron Deficiency Tolerance and Iron Accumulation in Rice by Combining the Knockdown of OsHRZ Ubiquitin Ligases with the Introduction of Engineered Ferric-chelate Reductase.
|
|
Chowdhury R., Nallusamy S., Shanmugam V., Loganathan A., Muthurajan R., Subramanian Kizhaeral Sivathapandian, Paramasivam J., Duraialagaraja S.
Biologia 2022 77 39-53
Genome‐wide understanding of evolutionary and functional relationships of rice Yellow Stripe‐Like (YSL) transporter family in comparison with other plant species
|
|
Zhang H., Li Y., Pu M., Xu P., Liang G., Yu D.
Plant Cell Environ. 2020 43(1) 261-274
Oryza sativa POSITIVE REGULATOR OF IRON DEFICIENCY RESPONSE 2 (OsPRI2) and OsPRI3 are involved in the maintenance of Fe homeostasis.
|
|
Liang G., Zhang H., Li Y., Pu M., Yang Y., Li C., Lu C., Xu P., Yu D.
J Integr Plant Biol 2020 62(5) 668-689
Oryza sativa FER-LIKE FE DEFICIENCY-INDUCED TRANSCRIPTION FACTOR (OsFIT/OsbHLH156) interacts with OsIRO2 to regulate iron homeostasis.
|
|
Kobayashi T., Ozu A., Kobayashi S., An G., Jeon J.S., Nishizawa N.K.
Plant Mol. Biol. 2019 101(4-5) 471-486
OsbHLH058 and OsbHLH059 transcription factors positively regulate iron deficiency responses in rice.
|
|
Shi X., Chen S., Peng Y., Wang Y., Chen J., Hu Z., Wang B., Li A., Chao D., Li Y., Teng S.
J Integr Plant Biol 2018 60(2) 112-129
TSC1 enables plastid development under dark conditions, contributing to rice adaptation to transplantation shock.
|
|
Aung M.S., Kobayashi T., Masuda H., Nishizawa N.K.
Physiol Plant 2018
Rice HRZ ubiquitin ligases are crucial for response to excess iron.
|
|
Zhang H., Li Y., Yao X., Liang G., Yu D.
Plant Physiol. 2017 175(1) 543-554
POSITIVE REGULATOR OF IRON HOMEOSTASIS1, OsPRI1, Facilitates Iron Homeostasis.
|
|
Wang B., Wei H., Xue Z., Zhang W.H.
Ann. Bot. 2017 119(6) 945-956
Gibberellins regulate iron deficiency-response by influencing iron transport and translocation in rice seedlings (Oryza sativa).
|
|
Kobayashi T., Itai R.N., Senoura T., Oikawa T., Ishimaru Y., Ueda M., Nakanishi H., Nishizawa N.K.
Plant Mol. Biol. 2016 91(4-5) 533-47
Jasmonate signaling is activated in the very early stages of iron deficiency responses in rice roots.
|
|
Agarwal S., Tripura Venkata VG., Kotla A., Mangrauthia S.K., Neelamraju S.
Gene 2014 546(2) 430-6
Expression patterns of QTL based and other candidate genes in Madhukar × Swarna RILs with contrasting levels of iron and zinc in unpolished rice grains.
|
|
Kobayashi T.a b, Nakanishi Itai R.c, Nishizawa N.K.b
Rice 2014 7
Iron deficiency responses in rice roots
|
|
Kobayashi T., Naoko K Nishizawa
Annu Rev Plant Biol 2012 63 131-52
Iron uptake, translocation, and regulation in higher plants.
|
|
Liu T., Zeng J., Xia K., Fan T., Li Y., Wang Y., Xu X., Zhang M.
Rice (N Y) 2012 5 12
Evolutionary expansion and functional diversification of oligopeptide transporter gene family in rice
|
|
Lee S., Kim Y.S., Jeon U.S., Kim Y.K., Schjoerring J.K., An G.
Mol. Cells 2012 33(3) 269-75
Activation of Rice nicotianamine synthase 2 (OsNAS2) enhances iron availability for biofortification.
|
|
Lee S., Ryoo N., Jeon J.S., Guerinot M.L., An G.
Mol. Cells 2012 33(2) 117-26
Activation of rice Yellow Stripe1-Like 16 (OsYSL16) enhances iron efficiency.
|
|
Ishimaru Y., Takahashi R., Bashir K., Shimo H., Senoura T., Sugimoto K., Ono K., Yano M., Ishikawa S., Arao T., Nakanishi H., Nishizawa N.K.
Sci Rep 2012 2 286
Characterizing the role of rice NRAMP5 in Manganese, Iron and Cadmium Transport.
|
|
Kakei Y., Ishimaru Y., Kobayashi T., Yamakawa T., Nakanishi H., Nishizawa N.K.
Plant Mol. Biol. 2012 79(6) 583-94
OsYSL16 plays a role in the allocation of iron.
|
|
Zheng L., Yamaji N., Yokosho K., Ma J.F.
Plant Cell 2012 24(9) 3767-82
YSL16 is a phloem-localized transporter of the copper-nicotianamine complex that is responsible for copper distribution in rice.
|
|
Masuda H., Ishimaru Y., Aung M.S., Kobayashi T., Kakei Y., Takahashi M., Higuchi K., Nakanishi H., Nishizawa N.K.
Sci Rep 2012 2 543
Iron biofortification in rice by the introduction of multiple genes involved in iron nutrition.
|
|
Wang L., Ying Y., Narsai R., Ye L., Zheng L., Tian J., Whelan J., Shou H.
Plant Cell Environ. 2012 36(1) 224-36.
Identification of OsbHLH133 as a regulator of iron distribution between roots and shoots in Oryza sativa.
|
|
Takanashi H., Ishimaru Y., Bashir K., Fujimoto M., Shimo H., An G., Nagasaka S., Nishizawa N.K., Nakanishi H., Tsutsumi N.
Nature Communications 2011 2 322
The rice mitochondrial iron transporter is essential for plant growth
|
|
Nozoye T,Nagasaka S,Kobayashi T,Takahashi M,Sato Y,Sato Y,Uozumi N,Nakanishi H,Nishizawa NK
J. Biol. Chem. 2011 286(7) 5446-54
Phytosiderophore efflux transporters are crucial for iron acquisition in graminaceous plants.
|
|
Ishimaru Y., Masuda H., Bashir K., Inoue H., Tsukamoto T., Takahashi M., Nakanishi H., Aoki N., Hirose T., Ohsugi R., Naoko K Nishizawa
Plant J. 2010 62(3) 379-90
Rice metal-nicotianamine transporter, OsYSL2, is required for the long-distance transport of iron and manganese.
|
|
Aoyama T,Kobayashi T,Takahashi M,Nagasaka S,Usuda K,Kakei Y,Ishimaru Y,Nakanishi H,Mori S,Nishizawa NK
Plant Mol. Biol. 2009 70 681-92
OsYSL18 is a rice iron(III)-deoxymugineic acid transporter specifically expressed in reproductive organs and phloem of lamina joints.
|
|
Kobayashi T,Itai RN,Ogo Y,Kakei Y,Nakanishi H,Takahashi M,Nishizawa NK
Plant J. 2009 60(6) 948-61
The rice transcription factor IDEF1 is essential for the early response to iron deficiency, and induces vegetative expression of late embryogenesis abundant genes.
|
|
Narayanan NN, Vasconcelos MW, Grusak MA.
Plant Physiol. Biochem. 2007 45(5) 277-86.
Expression profiling of Oryza sativa metal homeostasis genes in different rice cultivars using a cDNA macroarray.
|
|
Koike, S., H. Inoue, D. Mizuno, M. Takahashi, M. Nakanishi, S. Mori and N.K. Nishizawa
Plant J. 2004 39 (3) 415-424
OsYSL2 is a rice metal-nicotianamine transporter that is regulated by iron and expressed in the phloem.
|
|
Gross,J., Stein,J.R., Fett-Neto,A.G. and Fett,J.P.
Genet. Mol. Biol. 2003 26(4) 477-497
Iron homeostasis related genes in rice
|
|
DB Reference
|
|
Gramene ID
|
GR:0080050
|
|
Ontologies
|
|
Gene Ontology
|
iron ion homeostasis( GO:0055072 )
metal ion transport( GO:0030001 )
iron ion transmembrane transporter activity( GO:0005381 )
iron ion binding( GO:0005506 )
metal ion transmembrane transporter activity( GO:0046873 )
transmembrane transport( GO:0055085 )
membrane( GO:0016020 )
plasma membrane( GO:0005886 )
iron ion transport( GO:0006826 )
integral to membrane( GO:0016021 )
cellular response to iron ion starvation( GO:0010106 )
response to iron ion( GO:0010039 )
response to gibberellin stimulus( GO:0009739 )
|
|
Trait Ontology
|
iron sensitivity( TO:0000224 )
gibberellic acid sensitivity( TO:0000166 )
|
|
Plant Ontology
|
companion cell( PO:0000071 )
vascular bundle( PO:0005020 )
phloem( PO:0005417 )
plant ovary( PO:0009072 )
spikelet( PO:0009051 )
plant embryo( PO:0009009 )
seed maturation stage( PO:0007632 )
seed development stage( PO:0001170 )
endosperm development stage( PO:0007633 )
|
|
Related Strains
|
|
-
|
|
Phenotype images
|
|
-
|
|
Last updated
|
|
Jan 17, 2026
|
Update info.