Gene - Detail

Detail of Gene

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Basic Information
CGSNL Gene Symbol NAS3
Gene Symbol Synonym OsNAS3
Gene Name Synonym rice nicotianamine synthase3, NA synthase gene 3, Nicotianamine synthase 3, S-adenosyl-L-methionine:S-adenosyl-L-methionine:S-adenosyl-methionine 3-amino-3-carboxypropyltransferase 3
Allele osnas3-1
Chromosome No. 7
Explanation Nicotianamine synthase is a critical component in Fe acquisition in graminaceous plants. Nicotianamine and nicotianamine synthase play an important role in long-distance trasport of Fe in rice plants. EC= A2YQ58(indcica). Q0D3F2(japonica). TO:0006049: iron concentration. TO:0006053: zinc concentration. TO:0006052: copper concentration. GO:0120127: response to zinc ion starvation . GO:1990641: response to iron ion starvation. Candidate gene for qCo7.1 and qZn7.2 (QTL for Zn and Co concentrations). PO:0030123: panicle inflorescence.
Trait Class Biochemical character
Tolerance and resistance - Stress tolerance
cDNA Accession No. AK070656
MSU ID LOC_Os07g48980.1
RAP ID Os07g0689600
Links Oryzabase Chromosome View ( IRGSP 1.0 / Build5 )
RAP-DB ( IRGSP 1.0 / Build5 )
Related IDs List ( IRGSP 1.0 / Build5 )
INSD Accession List
(Test version)
Link to INSD Accession List
Link map Classical linkage map
Regon P., Dey S., Rehman M., Pradhan A.K., Chowra U., Tanti B., Talukdar A.D., Panda S.K.
Front Plant Sci 2022  13  798580
Transcriptomic Analysis Revealed Reactive Oxygen Species Scavenging Mechanisms Associated With Ferrous Iron Toxicity in Aromatic Keteki Joha Rice.
Liu C., Li N., Lu Z., Sun Q., Pang X., Xiang X., Deng C., Xiong Z., Shu K., Yang F., Hu Z.
Front Plant Sci 2022  13  839457
CG and CHG Methylation Contribute to the Transcriptional Control of OsPRR37-output Genes in Rice.
Cu S.T., Warnock N.I., Pasuquin J., Dingkuhn M., Stangoulis J.
Sci Rep 2021  11(1)  19230
A high-resolution genome-wide association study of the grain ionome and agronomic traits in rice Oryza sativa subsp. indica.
Wang S., Li L., Ying Y., Wang J., Shao J.F., Yamaji N., Whelan J., Ma J.F., Shou H.
New Phytol. 2020  225(3)  1247-1260
A transcription factor OsbHLH156 regulates Strategy II iron acquisition through localising IRO2 to the nucleus in rice.
Abbai R., Singh V.K., Nachimuthu V.V., Sinha P., Selvaraj R., Vipparla A.K., Singh A.K., Singh U.M., Varshney R.K., Kumar A.
Plant Biotechnol. J. 2019   
Haplotype analysis of key genes governing grain yield and quality traits across 3K RG panel reveals scope for the development of tailor-made rice with enhanced genetic gains.
Bashir K., Ishimaru Y., Itai R.N., Senoura T., Takahashi M., An G., Oikawa T., Ueda M., Sato A., Uozumi N., Nakanishi H., Nishizawa N.K.
Plant Mol. Biol. 2015  88(1-2)  165-76
Iron deficiency regulated OsOPT7 is essential for iron homeostasis in rice.
Agarwal S., Tripura Venkata VG., Kotla A., Mangrauthia S.K., Neelamraju S.
Gene 2014  546(2)  430-6
Expression patterns of QTL based and other candidate genes in Madhukar × Swarna RILs with contrasting levels of iron and zinc in unpolished rice grains.
Wang L., Ying Y., Narsai R., Ye L., Zheng L., Tian J., Whelan J., Shou H.
Plant Cell Environ. 2012  36(1)  224-36.
Identification of OsbHLH133 as a regulator of iron distribution between roots and shoots in Oryza sativa.
Anuradha K., Agarwal S., Rao Y.V., Rao K.V., Viraktamath B.C., Sarla N.
Gene 2012  508(2)  233-40
Mapping QTLs and candidate genes for iron and zinc concentrations in unpolished rice of Madhukar×Swarna RILs.
Suzuki M., Bashir K., Inoue H., Takahashi M., Nakanishi H., Nishizawa N.K.
Rice (N Y) 2012  5  9
Accumulation of starch in Zn-deficient rice
Johnson A.A., Kyriacou B., Callahan D.L., Carruthers L., Stangoulis J., Lombi E., Tester M.
PLoS ONE 2011  6(9)  e24476
Constitutive overexpression of the OsNAS gene family reveals single-gene strategies for effective iron- and zinc-biofortification of rice endosperm.
Lee S., Un Sil Jeon, Seung Jin Lee, Yoon-Keun Kim, Daniel Pergament Persson, Søren Husted, Jan K Schjørring, Kakei Y., Masuda H., Naoko K Nishizawa, An G.
Proc. Natl. Acad. Sci. U.S.A. 2009  106(51)  22014-9
Iron fortification of rice seeds through activation of the nicotianamine synthase gene.
Kobayashi T,Itai RN,Ogo Y,Kakei Y,Nakanishi H,Takahashi M,Nishizawa NK
Plant J. 2009  60(6)  948-61
The rice transcription factor IDEF1 is essential for the early response to iron deficiency, and induces vegetative expression of late embryogenesis abundant genes.
Ogo,Y., Itai,R.N., Nakanishi,H., Inoue,H., Kobayashi,T., Suzuki,M., Takahashi,M., Mori,S. and Nishizawa,N.K.
J. Exp. Bot. 2006  57(11)  2867-2878
Isolation and characterization of IRO2, a novel iron-regulated bHLH transcription factor in graminaceous plants
Nozoye T., Reiko Nakanishi Ita, Nagasaki S., Takahashi M., Nakanishi H., Mori S., Naoko K Nishikawa
Soil Sci Plant Nutr 2004  50(7)  1125-1131
Diurnal Changes in the Expression of Genes That Participate in Phytosiderophore Synthesis in Rice
Inoue, H., K. Higuchi, M. Takahashi, H. Nakanishi, S. Mori and N.K. Nishizawa
Plant J. 2003  36 (3)  366-381
Three rice nicotianamine synthase genes, OsNAS1, OsNAS2, and OsNAS3 are expressed in cells involved in long-distance transport of iron and differentially regulated by iron.
Higuchi K, Suzuki K, Nakanishi H, Yamaguchi H, Nishizawa NK, Mori S.
Plant Physiol. 1999  119(2)  471-480
Cloning of nicotianamine synthase genes, novel genes involved in the biosynthesis of phytosiderophores.
TextPresso Search Search textpresso for NAS3 ( Recent references may be retrievable, but without any warranty )
DB Reference
Gramene ID GR:0080049
Gene Ontology response to iron(II) ion( GO:0010040 )
circadian rhythm( GO:0007623 )
iron ion transport( GO:0006826 )
nicotianamine synthase activity( GO:0030410 )
nicotianamine biosynthetic process( GO:0030418 )
response to nickel ion( GO:0010045 )
response to copper ion( GO:0046688 )
response to iron ion( GO:0010039 )
response to zinc ion( GO:0010043 )
Trait Ontology iron sensitivity( TO:0000224 )
copper sensitivity( TO:0000021 )
zinc sensitivity( TO:0000351 )
Plant Ontology companion cell( PO:0000071 )
guard cell( PO:0000293 )
pericycle( PO:0006203 )
root( PO:0009005 )
vascular leaf( PO:0009025 )
seed( PO:0009010 )
0 seed germination stage( PO:0007057 )
radicle( PO:0020031 )
plumule( PO:0020032 )
leaf( PO:0025034 )
shoot system( PO:0009006 )
leaf sheath( PO:0020104 )
stem( PO:0009047 )
inflorescence( PO:0009049 )
spikelet( PO:0009051 )
Related Strains
Phenotype images
Last updated
Jun 22, 2022