Gene - Detail

Detail of Gene

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Basic Information
CGSNL Gene Symbol BRD1
Gene Symbol Synonym brd1, OsDWARF, DWARF, OsBR6ox, BR6ox, CYP85A1, CYP85A4, OsDWF, CYP85A1/OsDWARF, OsBRD1, OsCYP85A1
Gene Name Synonym brassinosteroid-dependent1, brassinosteroid-dependent 1, brassinosteroid-deficient dwarf1, brassinosteroid-deficient dwarf 1, Cytochrome P450 85A1, C6-oxidase, BR-6-oxidase, Dwarf protein, cytochrome P450 CYP85A4, brassinosteroid deficient1, BR-deficient dwarf1, BR-deficient dwarf 1, BR C-6 oxidase
Protein Name CYTOCHROME P450 85A1
Allele brd1, brd1-1, brd1-2, brd1-3
Chromosome No. 3
Explanation AB084385. Q8GSQ1. A dwarf due to defect in brassinosteroids (BRs) synthesis. This dwarf has characteristics as erect leaves, defects in skotomorhogenesis (dark-adapted morphogenesis), and the ability of exogenous brassinolide (BL) treatment to rescue the dwarf phenotype.Deficiency in this gene causes a dwarf due to brassinosteroid (BR) biosynthetic defect.
Trait Class Vegetative organ - Leaf
Vegetative organ - Culm
Seed - Morphological traits
Character as QTL - Yield and productivity
cDNA Accession No. AK101670
MSU ID LOC_Os03g40540.1
RAP ID Os03g0602300
Links Oryzabase Chromosome View ( IRGSP 1.0 / Build5 )
RAP-DB ( IRGSP 1.0 / Build5 )
Related IDs List ( IRGSP 1.0 / Build5 )
INSD Accession List
(Test version)
Link to INSD Accession List
Link map Classical linkage map
Li G., Yao X., Chen Z., Tian X., Lu L.
Int J Mol Sci 2023  24(7) 
The Overexpression of <i>Oryza sativa</i> L. <i>CYP85A1</i> Promotes Growth and Biomass Production in Transgenic Trees.
Wang J., Liu Y., Hu S., Xu J., Nian J., Cao X., Chen M., Cen J., Liu X., Zhang Z., Liu D., Zhu L., Hu J., Ren D., Gao Z., Shen L., Dong G., Zhang Q., Li Q., Yu S., Qian Q., Zhang G.
Int J Mol Sci 2022  23(15) 
<i>LEAF TIP RUMPLED 1</i> Regulates Leaf Morphology and salt tolerance in Rice.
Kim S.H., Shim K.C., Lee H.S., Jeon Y.A., Adeva C., Luong N.H., Ahn S.N.
Front Plant Sci 2022  13  985559
Brassinosteroid biosynthesis gene <i>OsD2</i> is associated with low-temperature germinability in rice.
Hwang O.J., Back K.
Molecules 2021  26(4) 
Suppression of Rice cryptochrome 1b Decreases Both Melatonin and Expression of Brassinosteroid Biosynthetic Genes Resulting in Salt Tolerance.
Zhang J., Gao X., Cai G., Wang Y., Li J., Du H., Wang R., Zhang H., Huang J.
Rice (N Y) 2021  14(1)  105
An adenylate kinase OsAK3 Involves Brassinosteroid Signaling and Grain Length in Rice (Oryza sativa L.).
Tian X., He M., Mei E., Zhang B., Tang J., Xu M., Liu J., Li X., Wang Z., Tang W., Guan Q., Bu Q.
Plant Cell 2021   
WRKY53 Integrates Classic Brassinosteroid Signaling and the Mitogen-Activated Protein Kinase Pathway to Regulate Rice Architecture and seed size.
Ke Y., Yuan M., Liu H., Hui S., Qin X., Chen J., Zhang Q., Li X., Xiao J., Zhang Q., Wang S.
Proc. Natl. Acad. Sci. U.S.A. 2020  117(7)  3867-3873
The versatile functions of OsALDH2B1 provide a genic basis for growth-defense trade-offs in rice.
Seo H., Kim S.H., Lee B.D., Lim J.H., Lee S.J., An G., Paek N.C.
Int J Mol Sci 2020  21(6) 
The Rice <i>Basic Helix-Loop-Helix 79</i> (<i>OsbHLH079</i>) Determines leaf angle and Grain Shape.
Xiao Y., Zhang G., Liu D., Niu M., Tong H., Chu C.
Plant J. 2020   
GSK2 stabilizes OFP3 to suppress brassinosteroid responses in rice.
Jiao X., Wang H., Yan J., Kong X., Liu Y., Chu J., Chen X., Fang R., Yan Y.
Plant Physiol. 2020  182(3)  1454-1466
Promotion of BR Biosynthesis by miR444 Is Required for Ammonium-Triggered Inhibition of Root Growth.
Qin R., Zeng D., Yang C., Akhter D., Alamin M., Jin X., Shi C.
Genes (Basel) 2018  9(6) 
<i>LTBSG1</i>, a New Allele of <i>BRD2</i>, Regulates Panicle and Grain Development in Rice by Brassinosteroid Biosynthetic Pathway.
Tong X., Wang Y., Sun A., Bello B.K., Ni S., Zhang J.
Int J Mol Sci 2018  19(12) 
<b>Notched Belly Grain 4, a Novel Allele of Dwarf 11, Regulates grain shape and Seed Germination in Rice (Oryza sativa L.)</b>.
Yuan H., Fan S., Huang J., Zhan S., Wang S., Gao P., Chen W., Tu B., Ma B., Wang Y., Qin P., Li S.
Rice (N Y) 2017  10(1)  25
08SG2/OsBAK1 regulates grain size and number, and functions differently in Indica and Japonica backgrounds in rice.
Yu H., Ruan B., Wang Z., Ren D., Zhang Y., Leng Y., Zeng D., Hu J., Zhang G., Zhu L., Gao Z., Chen G., Guo L., Chen W., Qian Q.
Front Plant Sci 2017  8  486
Fine Mapping of a Novel defective glume 1 (dg1) Mutant, Which Affects Vegetative and Spikelet Development in Rice.
Qiao S., Sun S., Wang L., Wu Z., Li C., Li X., Wang T., Leng L., Tian W., Lu T., Wang X.
Plant Cell 2017  29(2)  292-309
The RLA1/SMOS1 Transcription Factor Functions with OsBZR1 to Regulate Brassinosteroid Signaling and Rice Architecture.
Xiao Y., Liu D., Zhang G., Tong H., Chu C.
Front Plant Sci 2017  8  1698
Brassinosteroids Regulate OFP1, a DLT interacting protein, to Modulate Plant Architecture and Grain Morphology in Rice.
Swain D.M., Sahoo R.K., Srivastava V.K., Tripathy B.C., Tuteja R., Tuteja N.
Planta 2016   
Function of heterotrimeric G-protein gamma subunit RGG1 in providing salinity stress tolerance in rice by elevating detoxification of ROS.
Feng Z., Wu C., Wang C., Roh J., Zhang L., Chen J., Zhang S., Zhang H., Yang C., Hu J., You X., Liu X., Yang X., Guo X., Zhang X., Wu F., Terzaghi W., Kim S.K., Jiang L., Wan J.
J. Exp. Bot. 2016  67(14)  4241-53
SLG controls grain size and leaf angle by modulating brassinosteroid homeostasis in rice.
Tong H., Chu C.
Plant Cell 2016  28(4)  833-5
Reply: Brassinosteroid Regulates Gibberellin Synthesis to Promote Cell Elongation in Rice: Critical Comments on Ross and Quittenden's Letter.
Zhang X., Sun J., Cao X., Song X.
Plant Physiol. 2015  169(3)  2118-28
Epigenetic Mutation of RAV6 Affects leaf angle and Seed Size in Rice.
Chen Q., Xie Q., Gao J., Wang W., Sun B., Liu B., Zhu H., Peng H., Zhao H., Liu C., Wang J., Zhang J., Zhang G., Zhang Z.
J. Exp. Bot. 2015   
Characterization of Rolled and Erect Leaf 1 in regulating leave morphology in rice.
Zhang B., Wang X., Zhao Z., Wang R., Huang X., Zhu Y., Yuan L., Wang Y., Xu X., Burlingame A.L., Gao Y., Sun Y., Tang W.
Plant Physiol. 2015   
OsBRI1 activates BR signaling by preventing binding between the TPR and kinase domains of OsBSK3 via phosphorylation.
Gan L., Wu H., Wu D., Zhang Z., Guo Z., Yang N., Xia K., Zhou X., Oh K., Matsuoka M., Ng D., Zhu C.
Plant Sci. 2015  241  238-45
Methyl jasmonate inhibits lamina joint inclination by repressing brassinosteroid biosynthesis and signaling in rice.
Zhang C., Bai M.Y., Chong K.
Plant Cell Rep. 2014  33(5)  683-96
Brassinosteroid-mediated regulation of agronomic traits in rice.
Tong H.a, Xiao Y.a, Liu D.a, Gao S.a, Liu L.a, Yin Y.b, Jin Y.c, Qian Q.d, Chu C.a
Plant Cell 2014  26  4376-4393
Brassinosteroid regulates cell elongation by modulating gibberellin metabolism in ricec w open
Asahina M., Tamaki Y., Sakamoto T., Shibata K., Nomura T., Yokota T.
Phytochemistry 2014  104  21-9
Blue light-promoted rice leaf bending and unrolling are due to up-regulated brassinosteroid biosynthesis genes accompanied by accumulation of castasterone.
Wei L.a b, Gu L.a, Song X.a, Cui X.a b, Lu Z.a, Zhou M.a, Wang L.a, Hu F.c, Zhai J.d e, Meyers B.C.d e, Cao X.a
Proc. Natl. Acad. Sci. U.S.A. 2014  111  3877-3882
Dicer-like 3 produces transposable element-associated 24-nt siRNAs that control agricultural traits in rice
Sakamoto T., Kitano H., Fujioka S.
Plant Signal Behav 2013  8  e27117
An E3 ubiquitin ligase, ERECT LEAF1, functions in brassinosteroid signaling of rice.
Tong H., Liu L., Jin Y., Du L., Yin Y., Qian Q., Zhu L., Chu C.
Plant Cell 2012  24(6)  2562-77
DWARF AND LOW-TILLERING Acts as a Direct Downstream Target of a GSK3/SHAGGY-like kinase to Mediate Brassinosteroid Responses in Rice.
Je B.I., Piao H.L., Park S.J., Park S.H., Kim C.M., Xuan Y.H., Park S.H., Huang J., Do Choi Y., An G., Wong H.L., Fujioka S., Kim M.-C., Shimamoto K., Han C.-D.
Plant Cell 2010  22(6)  1777-1791
RAV-Like1 maintains brassinosteroid homeostasis via the coordinated activation of BRI1 and biosynthetic genes in rice.
Wang L,Wang Z,Xu Y,Joo SH,Kim SK,Xue Z,Xu Z,Wang Z,Chong K
Plant J. 2009  57  498-510
OsGSR1 is involved in crosstalk between gibberellins and brassinosteroids in rice.
Tanaka A,Nakagawa H,Tomita C,Shimatani Z,Ohtake M,Nomura T,Jiang CJ,Dubouzet JG,Kikuchi S,Sekimoto H,Yokota T,Asami T,Kamakura T,Mori M
Plant Physiol. 2009  151(2)  669-80
BRASSINOSTEROID UPREGULATED1, encoding a helix-loop-helix protein, is a novel gene involved in brassinosteroid signaling and controls bending of the lamina joint in rice.
Nakamura A,Fujioka S,Takatsuto S,Tsujimoto M,Kitano H,Yoshida S,Asami T,Nakano T
Plant Cell Physiol. 2009  50(9)  1627-35
Involvement of C-22-hydroxylated brassinosteroids in auxin-induced lamina joint bending in rice.
Tong H,Jin Y,Liu W,Li F,Fang J,Yin Y,Qian Q,Zhu L,Chu C
Plant J. 2009  58  803-16
DWARF AND LOW-TILLERING, a new member of the GRAS family, plays positive roles in brassinosteroid signaling in rice.
Kim BK,Fujioka S,Takatsuto S,Tsujimoto M,Choe S
Biochem. Biophys. Res. Commun. 2008  374  614-9
Castasterone is a likely end product of brassinosteroid biosynthetic pathway in rice.
Yang,G., Nakamura,H., Ichikawa,H., Kitano,H. and Komatsu,S.
Phytochemistry 2006  67(14)  1442-1454
OsBLE3, a brassinolide-enhanced gene, is involved in the growth of rice
Sakamoto,T., Morinaka,Y., Ohnishi,T., Sunohara,H., Fujioka,S., Ueguchi-Tanaka,M., Mizutani,M., Sakata,K., Takatsuto,S., Yoshida,S., Tanaka,H., Kitano,H. and Matsuoka,M.
Nat. Biotechnol. 2005  24(1)  105-109
Erect leaves caused by brassinosteroid deficiency increase biomass production and grain yield in rice.
Hong,Z., Ueguchi-Tanaka,M., Shimizu-Sato,S., Inukai,Y., Fujioka,S., Shimada,Y., Takatsuto,S., Agetsuma,M., Yoshida,S., Watanabe,Y., Uozu,S., Kitano,H., Ashikari,M. and Matsuoka,M.
Plant J. 2002  32(4)  495-508
Loss-of-function of a rice brassinosteroid biosynthetic enzyme, C-6 oxidase, prevents the organized arrangement and polar elongation of cells in the leaves and stem.
Mori, M., Nomura, T., Ooka, H., Ishizuka, M., Yokka, T. et al.
Plant Physiol. 2002  130  1152-1161
Isolation and characterization of a rice dwarf mutant with a defect in brassinosteroid biosynthesis.
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DB Reference
Gramene ID GR:0080017
Gene Ontology membrane( GO:0016020 )
electron transport chain( GO:0022900 )
heme binding( GO:0020037 )
integral to membrane( GO:0016021 )
brassinosteroid biosynthetic process( GO:0016132 )
response to ammonium ion( GO:0060359 )
skotomorphogenesis( GO:0009647 )
regulation of seed growth( GO:0080113 )
multicellular organismal development( GO:0007275 )
oxidation reduction( GO:0055114 )
monooxygenase activity( GO:0004497 )
electron carrier activity( GO:0009055 )
microtubule bundle formation( GO:0001578 )
iron ion binding( GO:0005506 )
response to blue light( GO:0009637 )
brassinosteroid homeostasis( GO:0010268 )
response to brassinosteroid stimulus( GO:0009741 )
response to jasmonic acid stimulus( GO:0009753 )
response to endogenous stimulus( GO:0009719 )
signal transduction( GO:0007165 )
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen( GO:0016705 )
Trait Ontology seed size( TO:0000391 )
leaf shape( TO:0000492 )
internode length( TO:0000145 )
brassinosteroid content( TO:0002676 )
leaf width( TO:0000370 )
plant height( TO:0000207 )
leaf length( TO:0000135 )
stem length( TO:0000576 )
jasmonic acid sensitivity( TO:0000172 )
leaf angle( TO:0000206 )
leaf rolling( TO:0000085 )
leaf sheath diameter( TO:0000642 )
root length( TO:0000227 )
blue light sensitivity( TO:0000159 )
leaf lamina joint bending( TO:0002688 )
brassinosteroid sensitivity( TO:0002677 )
Plant Ontology 4 root elongation stage( PO:0001031 )
Related Strains
Phenotype images
Last updated
Nov 15, 2023