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Basic Information
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CGSNL Gene Symbol
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SL
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Gene Symbol Synonym
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OsSL, sl (spl1), sl*, sl, spl1, CYP71P1, Os CYP71P1, T5H, OsT5H, CYP71A1, OsCYP71A1, OsLLM1, LLM1, LLM1/OsSL, ELL1, OsELL1, ELL1/SL, OsT5H1
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CGSNL Gene Name
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SEKIGUCHI LESION
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Gene Name Synonym
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Sekiguchi lesion, Cytochrome P450 71P1, tryptamine 5-hydroxylase, large lesion mimic 1, early lesion leaf 1
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Protein Name
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TRYPTAMINE 5-HYDROXYLASE
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Allele
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cyp71a1, llm1, sl, ell1, ost5h-1, ost5h-2, OsT5H-cas9-1, OsT5H-cas9-2, OsT5H-cas9-3
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Chromosome No.
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12
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Explanation
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Q2QUC5. Sekiguchi lesion (sl) mutation induces large orange to orang-brown lesions (Sekiguchi lesion) that eventurally occupy the entire surface area of leaves. First found in cv. Asahi by Sekiguchi & Furuta, and demonstrated by Kiyosawa that is controlled by a single recessive gene, sl. This is a hypersensitive reaction of plant cells to pathogen resulting the resistance to blast infection. CYP71A1 in Lu et al. 2018. TO:0000975: grain width. OsT5H1 in Bhowal et al. 2021.
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Trait Class
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Tolerance and resistance - Stress tolerance
Tolerance and resistance - Disease resistance
Tolerance and resistance - Insect resistance
Vegetative organ - Culm
Vegetative organ - Leaf
Coloration - Chlorophyll
Seed - Morphological traits - Grain shape
Tolerance and resistance - Lesion mimic
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Expression
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Sequence/Locus
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cDNA Accession No.
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AK071599
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MSU ID
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LOC_Os12g16720.1
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RAP ID
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Os12g0268000
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Links
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Oryzabase Chromosome View
(
IRGSP 1.0
/
Build5
)
RAP-DB
(
IRGSP 1.0
/
Build5
)
Related IDs List (
IRGSP 1.0
/
Build5
)
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INSD Accession List
(Test version)
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-
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Map
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Locate(cM)
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Link map
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Classical linkage map
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References
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Sahoo B., Nayak I., Parameswaran C., Kesawat M.S., Sahoo K.K., Subudhi H.N., Balasubramaniasai C., Prabhukarthikeyan S.R., Katara J.L., Dash S.K., Chung S.M., Siddiqui M.H., Alamri S., Samantaray S.
Plants (Basel) 2023 12(17)
A Comprehensive Genome-Wide Investigation of the Cytochrome 71 (<i>OsCYP71</i>) Gene Family: Revealing the Impact of Promoter and Gene Variants (Ser33Leu) of <i>OsCYP71P6</i> on Yield-Related Traits in Indica Rice (<i>Oryza sativa</i> L.).
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Yang Z., Zhang Z., Long X., Shi X., Wang D., Peng D., Ye S., Ding Z.
Phytopathology 2023
Clarifying the functional role of serotonin in <i>Meloidogyne graminicola</i> host plant parasitism by immunolocalization and RNA interference.
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Jiang M., Song Y., Yang R., Zheng C., Zheng Y., Zhang H., Li S., Tan Y., Huang J., Shu Q., Li R.
Plant Commun 2023 100674
Melatonin activates the OsbZIP79-OsABI5 module that orchestrates nitrogen and ROS homeostasis to alleviate nitrogen-limitation stress in rice.
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Lu X., Min W., Shi Y., Tian L., Li P., Ma T., Zhang Y., Luo C.
Front Plant Sci 2022 13 849553
Exogenous Melatonin Alleviates Alkaline Stress by Removing Reactive Oxygen Species and Promoting Antioxidant Defence in Rice Seedlings.
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Hwang O.J., Back K.
Antioxidants (Basel) 2022 11(5)
Molecular Regulation of Antioxidant Melatonin Biosynthesis by Brassinosteroid Acting as an Endogenous Elicitor of Melatonin Induction in Rice Seedlings.
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Zhang A., Jiang H., Chu H., Cao L., Chen J.
Curr Issues Mol Biol 2022 44(5) 2350-2361
Rice lesion mimic Gene Cloning and Association Analysis for disease resistance.
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Sun Y., Wang B., Ren J., Zhou Y., Han Y., Niu S., Zhang Y., Shi Y., Zhou J., Yang C., Ma X., Liu X., Luo Y., Jin C., Luo J.
Int J Mol Sci 2022 23(6)
OsbZIP18, a Positive Regulator of Serotonin Biosynthesis, Negatively Controls the UV-B Tolerance in Rice.
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Hwang O.J., Back K.
Molecules 2021 26(4)
Suppression of Rice cryptochrome 1b Decreases Both Melatonin and Expression of Brassinosteroid Biosynthetic Genes Resulting in Salt Tolerance.
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Bhowal B., Bhattacharjee A., Goswami K., Sanan-Mishra N., Singla-Pareek SL., Kaur C., Sopory S.
Int J Mol Sci 2021 22(20)
Serotonin and Melatonin Biosynthesis in Plants: Genome-Wide Identification of the Genes and Their Expression Reveal a Conserved Role in Stress and Development.
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Li R., Jiang M., Song Y., Zhang H.
Front Plant Sci 2021 12 727596
Melatonin Alleviates Low-Temperature Stress <i>via</i> ABI5-Mediated Signals During Seed Germination in Rice (<i>Oryza sativa</i> L.).
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Cui Y., Peng Y., Zhang Q., Xia S., Ruan B., Xu Q., Yu X., Zhou T., Liu H., Zeng D., Zhang G., Gao Z., Hu J., Zhu L., Shen L., Guo L., Qian Q., Ren D.
Plant J. 2021 105(4) 942-956
Disruption of EARLY LESION LEAF 1, encoding a cytochrome P450 monooxygenase, induces ROS accumulation and cell death in rice.
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Ruan B., Hua Z., Zhao J., Zhang B., Ren D., Liu C., Yang S., Zhang A., Jiang H., Yu H., Hu J., Zhu L., Chen G., Shen L., Dong G., Zhang G., Zeng D., Guo L., Qian Q., Gao Z.
Plant Biotechnol. J. 2019 17(7) 1344-1356
OsACL-A2 negatively regulates cell death and disease resistance in rice.
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Hong Y., Zhang Y., Sinumporn S., Yu N., Zhan X., Shen X., Chen D., Yu P., Wu W., Liu Q., Cao Z., Zhao C., Cheng S., Cao L.
Plant J. 2018
Premature leaf senescence 3, encoding a methyltransferase, is required for melatonin biosynthesis in rice.
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Xu X., Chen Z., Shi Y.F., Wang H.M., He Y., Shi L., Chen T., Wu J.L., Zhang X.B.
BMC Plant Biol. 2018 18(1) 264
Functional inactivation of OsGCNT induces enhanced disease resistance to Xanthomonas oryzae pv. oryzae in rice.
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Lu H.P., Luo T., Fu H.W., Wang L., Tan Y.Y., Huang J.Z., Wang Q., Ye G.Y., Gatehouse A.M.R., Lou Y.G., Shu Q.Y.
Nat Plants 2018 4(6) 338-344
Resistance of rice to insect pests mediated by suppression of serotonin biosynthesis.
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Yang Q.Q., Zhao D.S., Zhang C.Q., Wu H.Y., Li Q.F., Gu M.H., Sun S.S., Liu Q.Q.
Plant Physiol. 2018 176(3) 1965-1980
A Connection between Lysine and Serotonin Metabolism in Rice Endosperm.
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Nguyen Le T.N.b, Byeon Y.a, Kim Y.S.a, Back K.a
J. Pineal Res. 2013 55 40-45
Transient induction of melatonin biosynthesis in rice (Oryza sativa L.) during the reproductive stage Sangkyu Park1
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Jan A., Maruyama K., Todaka D., Kidokoro S., Abo M., Yoshimura E., Shinozaki K., Nakashima K., Kazuko Yamaguchi-Shinozaki
Plant Physiol. 2013 161(3) 1202-16
OsTZF1, a CCCH-tandem zinc finger protein, confers delayed senescence and stress tolerance in rice by regulating stress-related genes.
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Fujiwara T., Maisonneuve S., Isshiki M., Mizutani M., Chen L., Hann Ling Wong, Kawasaki T., Shimamoto K.
J. Biol. Chem. 2010 285(15) 11308-13
Sekiguchi lesion gene encodes a cytochrome P450 monooxygenase that catalyzes conversion of tryptamine to serotonin in rice.
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Ueno,M., Kihara,J., Honda,Y., Isota,J. and Arase,S.
J. Gen. Plant Pathol. 2004 70(6) 321-328
DNA fragmentation in Sekiguchi lesion mutants of rice infected with Magnaporthe grisea
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Ueno, M., H. Shibata, J. Kihara, Y. Honda and S. Arase
Plant J. 2003 36 (2) 215-228
Increased tryptophan decarboxylase and monoamine oxidase activities induce Sekiguchi lesion formation in rice infected with Magnaporthe grisea.
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Arase, S., K. Fujita, T. Uehara, Y. Honda and J. Isota
J. Phytopathology 2000 148 197-203
Light-enhanced resistance to Magnaporthe grisea infection in the rice Sekiguchi lesion mutants.
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Kiyosawa, S.
Bull. Natl. Inst. Agric. Sci., Ser.D 1970 21 61-71.
Inheritance of a particular sensitivity of the variety Sekiguchi Asahi to pathogens and chemicals and linkage relationship with blast resistance genes.
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Sekiguchi, Y. and T. Furuta
Ann. Phytopath. Soc. Japan 1965 30 71-72
On a rice mutant showing particular reaction to some spotting disease. Preliminary report.
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DB Reference
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Gramene ID
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GR:0060895
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Ontologies
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Gene Ontology
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nucleocytoplasmic transport( GO:0006913 )
monooxygenase activity( GO:0004497 )
heme binding( GO:0020037 )
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen( GO:0016705 )
electron carrier activity( GO:0009055 )
iron ion binding( GO:0005506 )
serotonin biosynthetic process( GO:0042427 )
defense response to insect( GO:0002213 )
endoplasmic reticulum( GO:0005783 )
chloroplast organization( GO:0009658 )
necrotic cell death( GO:0070265 )
programmed cell death( GO:0012501 )
response to light stimulus( GO:0009416 )
response to temperature stimulus( GO:0009266 )
callose localization( GO:0052545 )
response to cold( GO:0009409 )
response to hormone stimulus( GO:0009725 )
response to heat( GO:0009408 )
response to water deprivation( GO:0009414 )
response to absence of light( GO:0009646 )
response to salt stress( GO:0009651 )
melatonin biosynthetic process( GO:0030187 )
response to alkalinity( GO:0010446 )
response to UV-B( GO:0010224 )
response to abscisic acid stimulus( GO:0009737 )
response to ethylene stimulus( GO:0009723 )
response to cytokinin stimulus( GO:0009735 )
response to gibberellin stimulus( GO:0009739 )
response to auxin stimulus( GO:0009733 )
response to jasmonic acid stimulus( GO:0009753 )
response to brassinosteroid stimulus( GO:0009741 )
serotonin biosynthetic process from tryptophan( GO:0006587 )
endoplasmic reticulum membrane( GO:0005789 )
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Trait Ontology
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growth hormone content( TO:0000476 )
UV-B light sensitivity( TO:0000601 )
jasmonic acid sensitivity( TO:0000172 )
auxin sensitivity( TO:0000163 )
gibberellic acid sensitivity( TO:0000166 )
cytokinin sensitivity( TO:0000167 )
ethylene sensitivity( TO:0000173 )
abscisic acid sensitivity( TO:0000615 )
brassinosteroid sensitivity( TO:0002677 )
alkali sensitivity( TO:0000481 )
drought tolerance( TO:0000276 )
heat tolerance( TO:0000259 )
salt tolerance( TO:0006001 )
plant growth hormone sensitivity( TO:0000401 )
cold tolerance( TO:0000303 )
growth and development trait( TO:0000357 )
grain size( TO:0000397 )
grain length( TO:0000734 )
1000-dehulled grain weight( TO:0000592 )
filled grain number( TO:0000447 )
seed set percent( TO:0000455 )
flag leaf length( TO:0002757 )
plant height( TO:0000207 )
tiller number( TO:0000346 )
temperature response trait( TO:0000432 )
carotenoid content( TO:0000496 )
chlorophyll-b content( TO:0000295 )
chlorophyll-a content( TO:0000293 )
chlorophyll content( TO:0000495 )
hydrogen peroxide content( TO:0000605 )
chloroplast development trait( TO:0002715 )
stem borer resistance( TO:0000454 )
leaf blast disease resistance( TO:0000468 )
brown planthopper resistance( TO:0000424 )
insect damage resistance( TO:0000261 )
light sensitivity( TO:0000075 )
mimic response( TO:0000063 )
chemical stress sensitivity( TO:0000482 )
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Plant Ontology
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whole plant( PO:0000003 )
plant structure( PO:0009011 )
vascular leaf( PO:0009025 )
whole plant fruit ripening stage( PO:0007010 )
root( PO:0009005 )
inflorescence( PO:0009049 )
shoot system( PO:0009006 )
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Related Strains
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F Lines
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1
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Phenotype images
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Last updated
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Mar 20, 2026
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Update info.