Gene - Detail

Detail of Gene

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Basic Information
CGSNL Gene Symbol NAC4
Gene Symbol Synonym OsNAC4, NAC68, ONAC068, OnNAC4*, OnNAC4, OsNAC4/ONAC068
Gene Name Synonym NAC 4, NAC domain-containing protein 68, ONNAC GENE 4, OsNAC gene-4, OnNAC gene-4
Chromosome No. 1
Explanation This gene controls the formation of shoot apical meristem, organ separation and flower morphogenesis. AB028183. Q52QH4. Overexpression of OsNAC4 leads to hypersensitive response cell death (Kaneda et al. 2009). GO:1902183: regulation of shoot apical meristem development.
Trait Class Biochemical character
Vegetative organ - Shoot apical meristem(SAM)
Tolerance and resistance - Disease resistance
Tolerance and resistance - Insect resistance
Tolerance and resistance - Stress tolerance
cDNA Accession No. AK073848
MSU ID LOC_Os01g60020.1
RAP ID Os01g0816100
Links Oryzabase Chromosome View ( IRGSP 1.0 / Build5 )
RAP-DB ( IRGSP 1.0 / Build5 )
Related IDs List ( IRGSP 1.0 / Build5 )
INSD Accession List
(Test version)
Link to INSD Accession List
Link map Classical linkage map
Liu W.Z., Li Z.Y., Liu C., Yu X.T., Yu W.Q., Li P.
Genome 2023  66(6)  131-149
<i>Paenibacillus terrae</i> NK3-4 regulates the transcription of growth-related and stress resistance-related genes in rice.
Liu Z., Qiu J., Shen Z., Wang C., Jiang N., Shi H., Kou Y.
Plant Commun 2023    100626
The E3 ubiquitin ligase OsRGLG5 targeted by the Magnaporthe oryzae effector AvrPi9 confers basal resistance against rice blast.
Yang M., Sakruaba Y., Ishikawa T., Ohtsuki N., Kawai-Yamada M., Yanagisawa S.
Plant Physiol. 2023   
Chloroplastic Sec14-like proteins modulate growth and phosphate deficiency responses in Arabidopsis and rice.
Qiu J., Xie J., Chen Y., Shen Z., Shi H., Naqvi N.I., Qian Q., Liang Y., Kou Y.
Mol Plant 2022  15(4)  723-739
Warm temperature compromises JA-regulated basal resistance to enhance Magnaporthe oryzae infection in rice.
Khan I., Jan R., Asaf S., Khan A.L., Bilal S., Kim K.M., Al-Harrasi A.
Int J Mol Sci 2022  23(23) 
Genome and Transcriptome-Wide Analysis of <i>OsWRKY</i> and <i>OsNAC</i> Gene Families in <i>Oryza sativa</i> and Their Response to White-Backed Planthopper Infestation.
Zhang L.L., Huang Y.Y., Zheng Y.P., Liu X.X., Zhou S.X., Yang X.M., Liu S.L., Li Y., Li J.L., Zhao S.L., Wang H., Ji Y.P., Zhang J.W., Pu M., Zhao Z.X., Fan J., Wang W.M.
Plant J. 2022  110(1)  166-178
Osa-miR535 targets SQUAMOSA promoter binding protein-like 4 to regulate blast disease resistance in rice.
Chen J.F., Zhao Z.X., Li Y., Li T.T., Zhu Y., Yang X.M., Zhou S.X., Wang H., Zhao J.Q., Pu M., Feng H., Fan J., Zhang J.W., Huang Y.Y., Wang W.M.
Rice (N Y) 2021  14(1)  26
Fine-Tuning Roles of Osa-miR159a in Rice Immunity Against Magnaporthe oryzae and Development.
Li Y., Ting-Ting Li, Xiao-Rong He, Zhu Y., Feng Q., Xue-Mei Yang, Xin-Hui Zhou, Guo-Bang Li, Yun-Peng Ji, Jing-Hao Zhao, Zhi-Xue Zhao, Pu M., Shi-Xin Zhou, Ji-Wei Zhang, Yan-Yan Huang, Fan J., Wen-Ming Wang
Plant Biotechnol. J. 2021   
Blocking Osa-miR1871 enhances rice resistance against Magnaporthe oryzae and yield.
Butt H., Bazin J., Alshareef S., Eid A., Benhamed M., Reddy A.S.N., Crespi M., Mahfouz M.M.
Commun Biol 2021  4(1)  529
Overlapping roles of spliceosomal components SF3B1 and PHF5A in rice splicing regulation.
Li X.P., Ma X.C., Wang H., Zhu Y., Liu X.X., Li T.T., Zheng Y.P., Zhao J.Q., Zhang J.W., Huang Y.Y., Pu M., Feng H., Fan J., Li Y., Wang W.M.
Rice (N Y) 2020  13(1)  38
Osa-miR162a fine-tunes rice resistance to Magnaporthe oryzae and Yield.
Bai P., Park C.H., Shirsekar G., Songkumarn P., Bellizzi M., Wang G.L.
Mol. Plant Pathol. 2019  20(4)  599-608
Role of lysine residues of the Magnaporthe oryzae effector AvrPiz-t in effector- and PAMP-triggered immunity.
Sánchez-Sanuy F., Peris-Peris C., Tomiyama S., Okada K., Hsing Y.I., San Segundo B., Campo S.
BMC Plant Biol. 2019  19(1)  563
Osa-miR7695 enhances transcriptional priming in defense responses against the rice blast fungus.
Wang J., Liu X., Zhang A., Ren Y., Wu F., Wang G., Xu Y., Lei C., Zhu S., Pan T., Wang Y., Zhang H., Wang F., Tan Y.Q., Wang Y., Jin X., Luo S., Zhou C., Zhang X., Liu J., Wang S., Meng L., Wang Y., Chen X., Lin Q., Zhang X., Guo X., Cheng Z., Wang J., Tian Y., Liu S., Jiang L., Wu C., Wang E., Zhou J.M., Wang Y.F., Wang H., Wan J.
Cell Res. 2019  29(10)  820-831
A cyclic nucleotide-gated channel mediates cytoplasmic calcium elevation and disease resistance in rice.
Qin P., Fan S., Deng L., Zhong G., Zhang S., Li M., Chen W., Wang G., Tu B., Wang Y., Chen X., Ma B., Li S.
Plant Cell Physiol. 2018  59(5)  887-902
lml1, Encoding a Conserved eukaryotic release factor 1 Protein, Regulates Cell Death and Pathogen Resistance by Forming a Conserved Complex with SPL33 in Rice.
Li Z., Ding B., Zhou X., Wang G.L.
PLoS Pathog. 2017  13(1)  e1006157
The Rice Dynamin-Related Protein OsDRP1E Negatively Regulates Programmed Cell Death by Controlling the Release of cytochrome c from mitochondria.
Zhang H., Liu X.L., Zhang R.X., Yuan H.Y., Wang M.M., Yang H.Y., Ma H.Y., Liu D., Jiang C.J., Liang Z.W.
Front Plant Sci 2017  8  1580
Root Damage under Alkaline Stress Is Associated with Reactive Oxygen Species Accumulation in Rice (Oryza sativa L.).
Shirsekar G.S., Vega-Sánchez ME., Bordeos A., Baraoidan M., Swisshelm A., Fan J., Park C.H., Leung H., Wang G.L.
Mol. Plant Microbe Interact. 2014  27(6)  528-36
Identification and characterization of suppressor mutants of spl11- mediated cell death in rice.
Nuruzzaman M., Sharoni A.M., Kikuchi S.
Front Microbiol 2013  4  248
Roles of NAC transcription factors in the regulation of biotic and abiotic stress responses in plants.
Lv B.S.a b, Li X.W.a c, Ma H.Y.c, Sun Y.d, Wei L.X.c, Jiang C.J.e, Liang Z.W.c
Agron J 2013  105  1119-1128
Differences in growth and physiology of rice in response to different saline-alkaline stress factors
Nakayama A., Fukushima S., Goto S., Matsushita A., Shimono M., Sugano S., Jiang C.J., Akagi A., Yamazaki M., Inoue H., Takatsuji H.
BMC Plant Biol. 2013  13  150
Genome-wide identification of WRKY45-regulated genes that mediate benzothiadiazole-induced defense responses in rice.
Park C.H., Chen S., Shirsekar G., Zhou B., Khang C.H., Songkumarn P., Afzal A.J., Ning Y., Wang R., Bellizzi M., Valent B., Wang G.L.
Plant Cell 2012  24(11)  4748-62
The Magnaporthe oryzae effector AvrPiz-t targets the RING E3 ubiquitin ligase APIP6 to suppress pathogen-associated molecular pattern-triggered immunity in rice.
Taga Y,Takai R,Kaneda T,Matsui H,Isogai A,Che FS
Plant Signal Behav 2009  4(8)  740-2
Role of OsHSP90 and IREN, Ca2+ dependent nuclease, in plant hypersensitive cell death induced by transcription factor OsNAC4.
Shen H., Yin Y., Chen F., Xu Y., Richard A. Dixon
Bioenerg. Res. 2009  2  217–232
A Bioinformatic Analysis of NAC Genes for Plant Cell Wall Development in Relation to Lignocellulosic Bioenergy Production
Kaneda T,Taga Y,Takai R,Iwano M,Matsui H,Takayama S,Isogai A,Che FS
EMBO J. 2009  28  926-36
The transcription factor OsNAC4 is a key positive regulator of plant hypersensitive cell death.
Takai R,Isogai A,Takayama S,Che FS
Mol. Plant Microbe Interact. 2008  21  1635-42
Analysis of flagellin perception mediated by flg22 receptor OsFLS2 in rice.
Fang Y., You J., Xie K., Xie W., Xiong L.
Mol. Genet. Genomics 2008  280(6)  547-63
Systematic sequence analysis and identification of tissue-specific or stress-responsive genes of NAC transcription factor family in rice.
Lin,R., Zhao,W., Meng,X., Wang,M. and Peng,Y.
Plant Sci. 2007  172(1)  120-130
Rice gene OsNAC19 encodes a novel NAC-domain transcription factor and responds to infection by Magnaporthe grisea
Ooka H., Satoh K., Doi K., Nagata T., Otomo Y., Murakami K., Matsubara K., Osato N., Kawai J., Carninci P., Hayashizaki Y., Suzuki K., Kojima K., Takahara Y., Yamamoto K., Kikuchi S.
DNA Res. 2003  10(6)  239-47
Comprehensive analysis of NAC family genes in Oryza sativa and Arabidopsis thaliana.
Kikuchi,K., Ueguchi-Tanaka,M., Yoshida,K.T., Nagato,Y., Matsusoka,M. and Hirano,H.Y.
Mol. Gen. Genet. 2000  262(6)  1047-1051
Molecular analysis of the NAC gene family in rice.
Kikuchi, K., K.T. Yoshida, Y. Nagato and H.Y. Hirano
RGN 1998  15  160-161
Chromosomal location of the OsNAC genes.
Kikuchi, K., K.T. Yoshida, M. Uekuchi-Tanaka, M. Matsuoka, Y. Nagato and H.Y. Hirano
RGN 1997  14  125-126
Molecular characterization of the rice OsNAC genes.
TextPresso Search Search textpresso for NAC4 ( Recent references may be retrievable, but without any warranty )
DB Reference
Gramene ID GR:0060583
Gene Ontology response to bacterium( GO:0009617 )
response to symbiotic bacterium( GO:0009609 )
defense response to insect( GO:0002213 )
response to temperature stimulus( GO:0009266 )
DNA binding( GO:0003677 )
aminoacyl-tRNA ligase activity( GO:0004812 )
response to herbicide( GO:0009635 )
response to microbial phytotoxin( GO:0010188 )
response to salt stress( GO:0009651 )
defense response to fungus( GO:0050832 )
regulation of transcription( GO:0045449 )
transcription( GO:0006350 )
nucleus( GO:0005634 )
flower morphogenesis( GO:0048439 )
positive regulation of plant-type hypersensitive response( GO:0034052 )
response to alkalinity( GO:0010446 )
Trait Ontology salt tolerance( TO:0006001 )
jasmonic acid sensitivity( TO:0000172 )
bacterial disease resistance( TO:0000315 )
disease resistance( TO:0000112 )
shoot apical meristem development( TO:0006020 )
flower development trait( TO:0000622 )
alkali sensitivity( TO:0000481 )
herbicide sensitivity( TO:0000058 )
blast disease( TO:0000074 )
temperature response trait( TO:0000432 )
white-backed planthopper resistance( TO:0000205 )
Plant Ontology flower development stage( PO:0007615 )
Related Strains
Phenotype images
Last updated
Oct 12, 2023