Update info.Gene - Detail
Detail of Gene
| Basic Information | |
|---|---|
| CGSNL Gene Symbol | HWE1 |
| Gene Symbol Synonym | hwe1(t)*, hwe1, OsHWE1, OsEAF6/HWE1, OsEAF6, EAF6, HWS2, OsHWS2, MSHB12, OsMSHB12 |
| CGSNL Gene Name | HYBRID WEAKNESS E1 |
| Gene Name Synonym | hybrid weakness e1, hybrid weakness-e1, Esa1-associated factor 6, Hybrid Weakness and Sterility 2, Male Sterility-Related Hybrid Breakdown Locus on Chromosome 12 |
| Protein Name | ESA1-ASSOCIATED FACTOR 6 |
| Allele | Hwe1-j, hwe1-i, HWS2WYJ7, hwe2, hws2CG14, MSHB12Nip, MSHB12HHZ |
| Chromosome No. | 12 |
| Explanation | This gene causes hybrid weakness complementarily with hwe2. The hwe1 gene is located on chromosome 12 flanked by RFLP markers R1869 and S1437. CT830710. OsEAF6 paralogs. The BAS (an aromatic cultivar Basmati Surkh 89-15) genome harbors two duplicate paralogous copies MSHB12-1BAS and MSHB12-2BAS on chromosome 12. HWS1 in Liao et al. 2024. GO:1902562: H4 histone acetyltransferase complex. GO:0080186: developmental vegetative growth. GO:0061458: reproductive system development. TO:0000754: cardinal organ part morphology trait. PO:0030123: panicle inflorescence. |
| Trait Class |
Reproductive organ - Pollination, fertilization, fertility - Hybrid weakness
Reproductive organ - Pollination, fertilization, fertility - Hybrid sterility, hybrid weakness |
| Expression | |
| Sequence/Locus | |
| cDNA Accession No. | - |
| MSU ID |
LOC_Os12g20310.1
LOC_Os12g20310.2 |
| RAP ID |
Os12g0298600 |
| Links |
Oryzabase Chromosome View
(
IRGSP 1.0
/
Build5
)
RAP-DB ( IRGSP 1.0 / Build5 ) Related IDs List ( IRGSP 1.0 / Build5 ) |
|
INSD Accession List (Test version) |
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| Map | |
| Locate(cM) | |
| Link map | Classical linkage map |
| References | |
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Wang X., Zhang Z., Zhao J., Chen M., Gong J., Han Y., Wei X., Huang X., Fan J.
Mol. Breed. 2026 46(1) 9 Fine mapping and cloning of an intersubspecific reproductive isolation locus <i>MSHB1</i> in rice.
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Sun L., Ghouri F., Jin J., Zhong M., Huang W., Lu Z., Wu J., Liu X., Shahid M.Q.
Rice (N Y) 2025 18(1) 19 Interspecific Hybridization Enhanced Tolerance to Salinity and Cadmium Stress Through Modifying Biochemical, Physiological, and Resistance Gene Levels, Especially in Polyploid Rice: A Sustainable Way for Stress-Resilient Rice.
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Liao B., Xiang Y.H., Li Y., Yang K.Y., Shan J.X., Ye W.W., Dong N.Q., Kan Y., Yang Y.B., Zhao H.Y., Yu H.X., Lu Z.Q., Zhao Y., Zhao Q., Guo D., Guo S.Q., Lei J.J., Mu X.R., Cao Y.J., Han B., Lin H.X.
Nat Commun 2024 15(1) 996 Dysfunction of duplicated pair rice histone acetyltransferases causes segregation distortion and an interspecific reproductive barrier.
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Kubo T., Yoshimura A., Kurata N.
Front Plant Sci 2022 13 866404 Loss of OsEAF6, a Subunit of the Histone Acetyltransferase Complex, Causes Hybrid Breakdown in Intersubspecific Rice Crosses.
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Kubo, T. and A. Yoshimura
Theor. Appl. Genet. 2002 105 906-911 Genetic basis of hybrid breakdown in a Japonica/Indica cross of rice, Oryza sativa L.
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Kubo, T. and A. Yoshimura
RGN 1999 16 64-65. Linkage analysis of a gene responsible for F2 weakness in Japonica/Indica cross of rice.
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Kubo, T. and A. Yoshimura
Breeding Science 1998 48(Suppl. 1) 81 Linkage analysis of hybrid weakness in rice.
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| DB Reference | |
| Gramene ID | GR:0060463 |
| Ontologies | |
| Gene Ontology |
male gamete generation( GO:0048232 )
meiotic cell cycle( GO:0051321 ) multicellular organismal development( GO:0007275 ) recognition of pollen( GO:0048544 ) histone acetylation( GO:0016573 ) histone acetyltransferase complex( GO:0000123 ) gamete generation( GO:0007276 ) cell division( GO:0051301 ) nucleus( GO:0005634 ) regulation of gene expression, epigenetic( GO:0040029 ) regulation of transcription, DNA-dependent( GO:0006355 ) biotin metabolic process( GO:0006768 ) regulation of lipid biosynthetic process( GO:0046890 ) regulation of lipid transport( GO:0032368 ) thiamin metabolic process( GO:0006772 ) tapetal layer development( GO:0048658 ) pollen exine formation( GO:0010584 ) post-embryonic development( GO:0009791 ) embryo sac development( GO:0009553 ) cellularization of the embryo sac( GO:0009558 ) female gamete generation( GO:0007292 ) cell fate determination( GO:0001709 ) chromatin organization( GO:0006325 ) |
| Trait Ontology |
f2-generation sterility( TO:0000046 )
heterosis( TO:0000355 ) palea number( TO:0000209 ) anther shape( TO:0000214 ) pollen sterility( TO:0000053 ) seedling height( TO:0000019 ) seed set percent( TO:0000455 ) embryosac abortion( TO:0000416 ) hybrid incompatibility( TO:0000036 ) chlorophyll content( TO:0000495 ) pistil anatomy and morphology trait( TO:0000223 ) flower anatomy and morphology trait( TO:0000499 ) growth and development trait( TO:0000357 ) stem length( TO:0000576 ) male sterility( TO:0000437 ) female sterility( TO:0000358 ) panicle size( TO:0006032 ) spikelet number( TO:0000456 ) |
| Plant Ontology |
flower( PO:0009046 )
leaf( PO:0025034 ) stem( PO:0009047 ) spikelet( PO:0009051 ) inflorescence( PO:0009049 ) |
| Related Strains | |
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| Phenotype images | |
| - | |
| Last updated | |
| Aug 10, 2026 | |
