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Basic Information
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CGSNL Gene Symbol
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SPIN6
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Gene Symbol Synonym
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OsSPIN6, Spin6, SIP11, OsRhoGAP14, RhoGAP14
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CGSNL Gene Name
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SPIN6 HOMOLOG
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Gene Name Synonym
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SPL11-interacting Protein 6, SPL11-interacting protein6, SKIP interacting protein 11, SKIPa-interacting protein 11, SKIPa-interacting protein 11, Rho GTPase-activating protein 14
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Protein Name
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SPIN6 HOMOLOG
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Allele
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Chromosome No.
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7
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Explanation
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EU368701. a Rho GTPase-activating protein (Rho-GAP). the target of the E3 ligase SPL11. Component involved in SPL11-mediated PCD and defense. GO:1900425: negative regulation of defense response to bacterium. GO:2000377: regulation of reactive oxygen species metabolic process.
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Trait Class
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Tolerance and resistance - Disease resistance
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Expression
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Sequence/Locus
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cDNA Accession No.
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AK103870
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MSU ID
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LOC_Os07g46450.1
LOC_Os07g46450.2
LOC_Os07g46450.3
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RAP ID
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Os07g0658300
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Links
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Oryzabase Chromosome View
(
IRGSP 1.0
/
Build5
)
RAP-DB
(
IRGSP 1.0
/
Build5
)
Related IDs List (
IRGSP 1.0
/
Build5
)
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INSD Accession List
(Test version)
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-
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Map
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Locate(cM)
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Link map
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Classical linkage map
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References
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Fang C., Nie Y., Bi Y., An W., Jia D., Liang W.
Rice (N Y) 2025 18(1) 83
Genome-Wide Identification of the RhoGAP Gene Family and Main Function of OsRhoGAP2 in Seed Germination of Rice by Transcriptome Analysis.
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PLoS Pathog. 2015 11(4) e1004807
Correction: The RhoGAP SPIN6 Associates with SPL11 and OsRac1 and Negatively Regulates Programmed Cell Death and Innate Immunity in Rice.
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Liu J., Park C.H., He F., Nagano M., Wang M., Bellizzi M., Zhang K., Zeng X., Liu W., Ning Y., Kawano Y., Wang G.L.
PLoS Pathog. 2015 11(2) e1004629
The RhoGAP Spin6 associates with SPL11 and OsRac1 and negatively regulates programmed cell death and innate immunity in rice.
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Zhang H., Liu J., He F., Wang Z., Ning Y., Wang G.L.
Plant Signal Behav 2015 10(8) e1039212
OsHUB1 and OsHub2 interact with SPIN6 and form homo- and hetero-dimers in rice.
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Liu J., Li W., Ning Y., Shirsekar G., Wang X., Dai L., Wang Z., Liu W., Wang G.L.
Plant Physiol. 2012 160(1) 28-37
The U-box E3 ligase SPL11/PUB13 Is a Convergence Point of Defense and Flowering Signaling in Plants.
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Hou X,Xie K,Yao J,Qi Z,Xiong L
Proc. Natl. Acad. Sci. U.S.A. 2009 106 6410-5
A homolog of human ski-interacting protein in rice positively regulates cell viability and stress tolerance.
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DB Reference
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Gramene ID
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-
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Ontologies
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Gene Ontology
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GTPase activator activity( GO:0005096 )
signal transduction( GO:0007165 )
negative regulation of defense response( GO:0031348 )
negative regulation of programmed cell death( GO:0043069 )
negative regulation of innate immune response( GO:0045824 )
defense response to fungus( GO:0050832 )
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Trait Ontology
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blast disease( TO:0000074 )
bacterial blight disease resistance( TO:0000175 )
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Plant Ontology
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-
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Related Strains
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-
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Phenotype images
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-
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Last updated
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Dec 7, 2025
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Update info.