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Basic Information
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CGSNL Gene Symbol
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CERK1
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Gene Symbol Synonym
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OsCERK1, OsLysM-RLK9, Os-CERK1, Os-LysM-RLK9, OsLysMRLK9, OsCERK1/OsLYK9, OsLYK9, LYK9
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CGSNL Gene Name
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CHITIN ELICITOR RECEPTOR KINASE 1
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Gene Name Synonym
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chitin elicitor receptor kinase 1, chitinelicitor receptor kinase-1, LysM receptor-like kinase 9
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Protein Name
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CHITIN ELICITOR RECEPTOR KINASE 1
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Allele
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oscerk1, Oscerk1, Oscerk1-1, cerk1, cerk1-2, oscerk1-KO
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Chromosome No.
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8
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Explanation
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rice NFR1/LYK3 ortholog. GO:0035556:intracellular signal transduction. GO:0061057: peptidoglycan recognition protein signaling pathway. GO:0036377: arbuscular mycorrhizal association. GO:1903409: reactive oxygen species biosynthetic process. GO:0140426: pathogen-associated molecular pattern receptor signaling pathway. GO:2000023: regulation of lateral root development. TO:0001162: Lepidoptera damage response trait.
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Trait Class
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Tolerance and resistance
Tolerance and resistance - Insect resistance
Tolerance and resistance - Disease resistance
Character as QTL - Yield and productivity
Vegetative organ - Root
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Expression
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Sequence/Locus
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cDNA Accession No.
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AK111766
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MSU ID
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LOC_Os08g42580.1
LOC_Os08g42580.4
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RAP ID
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Os08g0538300
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Links
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Oryzabase Chromosome View
(
IRGSP 1.0
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Build5
)
RAP-DB
(
IRGSP 1.0
/
Build5
)
Related IDs List (
IRGSP 1.0
/
Build5
)
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INSD Accession List
(Test version)
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-
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Map
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Locate(cM)
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Link map
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Classical linkage map
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References
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Su Z., Zhou S., Yu S., Ning X., Fu Q., Fu Q., Zhao Q., Ma J., Niu C., Kong Y., Peng Y., Ming Z.
Plant Commun 2026 7(3) 101677
Structural basis of OsCERK1-mediated signal activation and transduction in rice immunity and symbiosis.
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Yan Y., Wang H., Bi Y., Tariq L., Song F.
J Integr Plant Biol 2025 67(5) 1199-1201
Rice E3 ubiquitin ligases balance immunity and yield through non-proteolytic ubiquitination.
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Kanda Y., Shinya T., Wari D., Hojo Y., Fujiwara Y., Tsuchiya W., Fujimoto Z., Thomma BPHJ., Nishizawa Y., Kamakura T., Galis I., Mori M.
Plant J. 2025 121(1) e17157
Chitin-signaling-dependent responses to insect oral secretions in rice cells propose the involvement of chitooligosaccharides in plant defense against herbivores.
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Molla K.A.
Plant Cell 2024
A trick for a treat: False smut pathogen manipulates plant defense to gain access to rice flower.
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Wang G., Chen X., Yu C., Shi X., Lan W., Gao C., Yang J., Dai H., Zhang X., Zhang H., Zhao B., Xie Q., Yu N., He Z., Zhang Y., Wang E.
Nature 2024 629(8014) 1158-1164
Release of a ubiquitin brake activates OsCERK1-triggered immunity in rice.
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Li C., Gong B.Q., Luo S., Wang T., Long R., Jiang X., Deng Y.Z., Li J.F.
Plant Physiol. 2024
Engineering a conserved immune coreceptor into a primed state enhances fungal resistance in crops without growth penalty.
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Li G.B., Liu J., He J.X., Li G.M., Zhao Y.D., Liu X.L., Hu X.H., Zhang X., Wu J.L., Shen S., Liu X.X., Zhu Y., He F., Gao H., Wang H., Zhao J.H., Li Y., Huang F., Huang Y.Y., Zhao Z.X., Zhang J.W., Zhou S.X., Ji Y.P., Pu M., He M., Chen X., Wang J., Li W., Wu X.J., Ning Y., Sun W., Xu Z.J., Wang W.M., Fan J.
Plant Cell 2024
Rice false smut virulence protein subverts host chitin perception and signaling at lemma and palea for floral infection.
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Xu Y., Tu Y., Feng J., Peng Z., Peng Y., Huang J.
Plants (Basel) 2024 13(14)
Arbuscular Mycorrhizal Fungi Mediate the Acclimation of Rice to Submergence.
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Miyata K., Hosotani M., Akamatsu A., Takeda N., Jiang W., Sugiyama T., Takaoka R., Matsumoto K., Abe S., Shibuya N., Kaku H.
Plant Cell Physiol. 2023 64(4) 378-391
OsSYMRK Plays an Essential Role in AM Symbiosis in Rice (Oryza sativa).
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Sahu K.P., Kumar A., Sakthivel K., Reddy B., Kumar M., Patel A., Sheoran N., Gopalakrishnan S., Prakash G., Rathour R., Gautam R.K.
Environ Microbiome 2022 17(1) 28
Deciphering core phyllomicrobiome assemblage on rice genotypes grown in contrasting agroclimatic zones: implications for phyllomicrobiome engineering against blast disease.
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Miyata K., Hasegawa S., Nakajima E., Nishizawa Y., Kamiya K., Yokogawa H., Shirasaka S., Maruyama S., Shibuya N., Kaku H.
Plant Biotechnol (Tokyo) 2022 39(2) 119-128
OsCERK2/OsRLK10, a homolog of OsCERK1, has a potential role for chitin-triggered immunity and arbuscular mycorrhizal symbiosis in rice.
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Chiu C.H., Roszak P., Orvošová M., Paszkowski U.
Curr. Biol. 2022 32(20) 4428-4437.e3
Arbuscular mycorrhizal fungi induce lateral root development in angiosperms via a conserved set of MAMP receptors.
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Patel A., Sahu K.P., Mehta S., Balamurugan A., Kumar M., Sheoran N., Kumar S., Krishnappa C., Ashajyothi M., Kundu A., Goyal T., Narayanasamy P., Kumar A.
Front Microbiol 2022 13 1035602
Rice leaf endophytic <i>Microbacterium testaceum</i>: Antifungal actinobacterium confers immunocompetence against rice blast disease.
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Sahu K.P., Patel A., Kumar M., Sheoran N., Mehta S., Reddy B., Eke P., Prabhakaran N., Kumar A.
Front Microbiol 2021 12 780458
Integrated Metabarcoding and Culturomic-Based Microbiome Profiling of Rice Phyllosphere Reveal Diverse and Functional Bacterial Communities for blast disease Suppression.
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Zhang C., He J., Dai H., Wang G., Zhang X., Wang C., Shi J., Chen X., Wang D., Wang E.
Proc. Natl. Acad. Sci. U.S.A. 2021 118(16)
Discriminating symbiosis and immunity signals by receptor competition in rice.
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Nasir F., Bahadur A., Lin X., Gao Y., Tian C.
J. Exp. Bot. 2021 72(5) 1546-1557
Novel insights into host receptors and receptor-mediated signaling that regulate arbuscular mycorrhizal symbiosis.
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Wang D., Wang H., Liu Q., Tu R., Zhou X., Zhang Y., Wu W., Yu P., Chen D., Zhan X., Cao L., Cheng S., Shen X.
Plant Cell Rep. 2021 40(5) 835-850
Reduction of OsMPK6 activity by a R89K mutation induces cell death and bacterial blight resistance in rice.
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Hou H., Fang J., Liang J., Diao Z., Wang W., Yang D., Li S., Tang D.
Int J Mol Sci 2020 21(19)
<i>OsExo70B1</i> Positively Regulates Disease Resistance to <i>Magnaporthe oryzae</i> in Rice.
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He J., Zhang C., Dai H., Liu H., Zhang X., Yang J., Chen X., Zhu Y., Wang D., Qi X., Li W., Wang Z., An G., Yu N., He Z., Wang Y.F., Xiao Y., Zhang P., Wang E.
Mol Plant 2019 12(12) 1561-1576
A LysM Receptor Heteromer Mediates Perception of Arbuscular Mycorrhizal Symbiotic Signal in Rice.
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Wang J., Liu X., Zhang A., Ren Y., Wu F., Wang G., Xu Y., Lei C., Zhu S., Pan T., Wang Y., Zhang H., Wang F., Tan Y.Q., Wang Y., Jin X., Luo S., Zhou C., Zhang X., Liu J., Wang S., Meng L., Wang Y., Chen X., Lin Q., Zhang X., Guo X., Cheng Z., Wang J., Tian Y., Liu S., Jiang L., Wu C., Wang E., Zhou J.M., Wang Y.F., Wang H., Wan J.
Cell Res. 2019 29(10) 820-831
A cyclic nucleotide-gated channel mediates cytoplasmic calcium elevation and disease resistance in rice.
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Yamaguchi K., Yoshimura Y., Nakagawa S., Mezaki H., Yoshimura S., Kawasaki T.
Biosci. Biotechnol. Biochem. 2019 83(2) 281-290
OsDRE2 contributes to chitin-triggered response through its interaction with OsRLCK185.
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Wang C., Wang G., Zhang C., Zhu P., Dai H., Yu N., He Z., Xu L., Wang E.
Mol Plant 2017 10(4) 619-633
OsCERK1-Mediated Chitin Perception and Immune Signaling Requires Receptor-like Cytoplasmic Kinase 185 to Activate an MAPK Cascade in Rice.
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Carotenuto G., Chabaud M., Miyata K., Capozzi M., Takeda N., Kaku H., Shibuya N., Nakagawa T., Barker D.G., Genre A.
New Phytol. 2017 214(4) 1440-1446
The rice LysM receptor-like kinase OsCERK1 is required for the perception of short-chain chitin oligomers in arbuscular mycorrhizal signaling.
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Yamada K., Yamaguchi K., Yoshimura S., Terauchi A., Kawasaki T.
Plant Cell Physiol. 2017
Conservation of chitin-induced MAPK signaling pathways in rice and Arabidopsis.
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Li Z., Ao Y., Feng D., Liu J., Wang J., Wang H.B., Liu B.
Rice (N Y) 2017 10(1) 6
OsRLCK 57, OsRLCK107 and OsRLCK118 Positively Regulate Chitin- and PGN-Induced Immunity in Rice.
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Miyata K., Hayafune M., Kobae Y., Kaku H., Nishizawa Y., Masuda Y., Shibuya N., Nakagawa T.
Plant Cell Physiol. 2016
Evaluation of the Role of the LysM Receptor-Like Kinase, OsNFR5/OsRLK2 for AM Symbiosis in Rice.
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Akamatsu A., Shimamoto K., Kawano Y.
Curr. Genomics 2016 17(4) 297-307
Crosstalk of Signaling Mechanisms Involved in Host Defense and Symbiosis Against Microorganisms in Rice.
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Akamatsu A., Uno K., Kato M., Wong H.L., Shimamoto K., Kawano Y.
Plant Signal Behav 2015 10(7) e1044702
New insights into the dimerization of small GTPase Rac/ROP guanine nucleotide exchange factors in rice.
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Ao Y., Li Z., Feng D., Xiong F., Liu J., Li J.F., Wang M., Wang J., Liu B., Wang H.B.
Plant J. 2014
OsCERK1 and OsRLCK176 play important roles in peptidoglycan and chitin signaling in rice innate immunity.
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Wang W., Xie Z.P., Staehelin C.
Plant J. 2014 78(1) 56-69
Functional analysis of chimeric lysin motif domain receptors mediating Nod factor-induced defense signaling in Arabidopsis thaliana and chitin-induced nodulation signaling in Lotus japonicus.
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Hayafune M.a, Berisio R.b, Marchetti R.c, Silipo A.c, Kayama M.a, Desaki Y.a, Arima S.a, Squeglia F.b, Ruggiero A.b, Tokuyasu K.d, Molinaro A.c, Kaku H.a, Shibuya N.a
Proc. Natl. Acad. Sci. U.S.A. 2014 111 E404-E413
Chitin-induced activation of immune signaling by the rice receptor CEBiP relies on a unique sandwich-type dimerization
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Miyata K., Kozaki T., Kouzai Y., Ozawa K., Ishii K., Asamizu E., Okabe Y., Umehara Y., Miyamoto A., Kobae Y., Akiyama K., Kaku H., Nishizawa Y., Shibuya N., Nakagawa T.
Plant Cell Physiol. 2014 55(11) 1864-72
The Bifunctional Plant Receptor, OsCERK1, Regulates Both Chitin-Triggered Immunity and Arbuscular Mycorrhizal Symbiosis in Rice.
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Kouzai Y., Mochizuki S., Nakajima K., Desaki Y., Hayafune M., Miyazaki H., Yokotani N., Ozawa K., Minami E., Kaku H., Shibuya N., Nishizawa Y.
Mol. Plant Microbe Interact. 2014 27(9) 975-82
Targeted gene disruption of OsCERK1 reveals its indispensable role in chitin perception and involvement in the peptidoglycan response and immunity in rice.
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Yamaguchi K., Yamada K., Ishikawa K., Yoshimura S., Hayashi N., Uchihashi K., Ishihama N., Kishi-Kaboshi M., Takahashi A., Tsuge S., Ochiai H., Tada Y., Shimamoto K., Yoshioka H., Kawasaki T.
Cell Host Microbe 2013 13(3) 347-57
A receptor-like cytoplasmic kinase targeted by a plant pathogen effector is directly phosphorylated by the chitin receptor and mediates rice immunity.
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Akamatsu A., Wong H.L., Fujiwara M., Okuda J., Nishide K., Uno K., Imai K., Umemura K., Kawasaki T., Kawano Y., Shimamoto K.
Cell Host Microbe 2013 13(4) 465-76
An OsCEBiP/OsCERK1-OsRacGEF1-OsRac1 Module Is an Essential Early Component of Chitin-Induced Rice Immunity.
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Kawano Y., Shimamoto K.
Curr. Opin. Plant Biol. 2013 16(4) 496-504
Early signaling network in rice PRR-mediated and R-mediated immunity.
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Liu B., Li J.F., Ao Y., Li Z., Liu J., Feng D., Qi K., He Y., Zeng L., Wang J., Wang H.B.
Plant Signal Behav 2013 8(2)
OsLYP4 and OsLYP6 play critical roles in rice defense signal transduction.
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Shinya T., Motoyama N., Ikeda A., Wada M., Kamiya K., Hayafune M., Kaku H., Naoto S.
Plant Cell Physiol. 2012 53(10) 1696-706
Functional characterization of CEBiP and CERK1 homologs in Arabidopsis and rice reveals the presence of different chitin receptor systems in plants.
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Kim S.H., Oikawa T., Kyozuka J., Wong H.L., Umemura K., Kishi-Kaboshi M., Takahashi A., Kawano Y., Kawasaki T., Shimamoto K.
Plant Cell Physiol. 2012 53(4) 740-54
The bHLH Rac Immunity1 (RAI1) Is Activated by OsRac1 via OsMAPK3 and OsMAPK6 in Rice Immunity.
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Liu B., Li J.F., Ao Y., Qu J., Li Z., Su J., Zhang Y., Liu J., Feng D., Qi K., He Y., Wang J., Wang H.B.
Plant Cell 2012 24(8) 3406-19
Lysin Motif-Containing Proteins LYP4 and LYP6 Play Dual Roles in Peptidoglycan and Chitin Perception in Rice Innate Immunity.
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Shimizu T., Nakano T., Takamizawa D., Desaki Y., Ishii-Minami N., Nishizawa Y., Minami E., Okada K., Yamane H., Kaku H., Shibuya N.
Plant J. 2010 64(2) 204-214
Two LysM receptor molecules, CEBiP and OsCERK1, cooperatively regulate chitin elicitor signaling in rice.
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Chen L.
Thesis 2010
Rac/Rop Small GTPases in Rice Innate Immunity
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Chen L., Hamada S., Fujiwara M., Zhu T., Nguyen Phuong Thao, Hann Ling Wong, Krishna P., Ueda T., Kaku H., Shibuya N., Kawasaki T., Shimamoto K.
Cell Host Microbe 2010 7(3) 185-96
The Hop/Sti1-Hsp90 chaperone complex facilitates the maturation and transport of a PAMP receptor in rice innate immunity.
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DB Reference
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Gramene ID
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-
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Ontologies
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Gene Ontology
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ATP binding( GO:0005524 )
symbiosis, encompassing mutualism through parasitism( GO:0044403 )
defense response to bacterium( GO:0042742 )
protein serine/threonine kinase activity( GO:0004674 )
detection of molecule of fungal origin( GO:0032491 )
transmembrane receptor protein kinase activity( GO:0019199 )
defense response to fungus, incompatible interaction( GO:0009817 )
response to peptidoglycan( GO:0032494 )
endoplasmic reticulum( GO:0005783 )
induction by symbiont of defense-related host reactive oxygen species production( GO:0052064 )
pathogen-associated molecular pattern dependent induction by symbiont of host innate immunity( GO:0052033 )
response to symbiotic fungus( GO:0009610 )
nodulation( GO:0009877 )
calcium-mediated signaling( GO:0019722 )
positive regulation of innate immune response( GO:0045089 )
defense response to fungus( GO:0050832 )
positive regulation of MAPKKK cascade( GO:0043410 )
positive regulation of calcium-mediated signaling( GO:0050850 )
response to chitin( GO:0010200 )
plasma membrane( GO:0005886 )
response to molecule of bacterial origin( GO:0002237 )
cytosolic calcium ion homeostasis( GO:0051480 )
response to bacterium( GO:0009617 )
response to symbiotic bacterium( GO:0009609 )
response to symbiont( GO:0009608 )
detection of symbiotic fungus( GO:0009603 )
lateral root development( GO:0048527 )
positive regulation of respiratory burst( GO:0060267 )
respiratory burst during defense response( GO:0002679 )
detection of insect( GO:0009601 )
defense response to insect( GO:0002213 )
positive regulation of hydrogen peroxide biosynthetic process( GO:0010729 )
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Trait Ontology
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disease resistance( TO:0000112 )
bacterial disease resistance( TO:0000315 )
fungal disease resistance( TO:0000439 )
blast disease( TO:0000074 )
lateral root number( TO:0001013 )
yield trait( TO:0000371 )
false smut disease resistance( TO:0000129 )
hydrogen peroxide content( TO:0000605 )
insect damage resistance( TO:0000261 )
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Plant Ontology
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root epidermis( PO:0006036 )
root cortex( PO:0000258 )
root development stage( PO:0007520 )
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Related Strains
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Phenotype images
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Last updated
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Jul 31, 2026
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Update info.