Gene - Detail

Detail of Gene

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Basic Information
CGSNL Gene Symbol MPK6
Gene Symbol Synonym OsMPK6, OsDR6, DR6, OsMPK4, MPK4, OsMAPK4, MAPK4
Gene Name Synonym mitogen-activated protein kinase 6, MAP kinase 4
Allele osmpk6
Chromosome No. 10
Explanation EF174189. FJ621301. Q336X9. defense-responsive protein. OsMPK4 in Wang et al. 2014, Mohanta et al. 2015, Jalmi and Sinha 2016, Li et al. 2021, Jing et al. 2021, Yang et al. 2021, Wang et al. 2023. GO:1903426: regulation of reactive oxygen species biosynthetic process. GO:0140426: pathogen-associated molecular pattern receptor signaling pathway.
Trait Class Biochemical character
Tolerance and resistance
Tolerance and resistance - Stress tolerance
Tolerance and resistance - Disease resistance
Tolerance and resistance - Insect resistance
Character as QTL - Yield and productivity
Vegetative organ - Culm
Reproductive organ - panicle
cDNA Accession No. AK111579
MSU ID LOC_Os10g38950.1
RAP ID Os10g0533600
Links Oryzabase Chromosome View ( IRGSP 1.0 / Build5 )
RAP-DB ( IRGSP 1.0 / Build5 )
Related IDs List ( IRGSP 1.0 / Build5 )
INSD Accession List
(Test version)
Link map Classical linkage map
Wang S., Han S., Zhou X., Zhao C., Guo L., Zhang J., Liu F., Huo Q., Zhao W., Guo Z., Chen X.
Plant Cell 2023  35(6)  2391-2412
Phosphorylation and ubiquitination of OsWRKY31 are integral to OsMKK10-2-mediated defense responses in rice.
Lv Y., Ma J., Wei H., Xiao F., Wang Y., Jahan N., Hazman M., Qian Q., Shang L., Guo L.
Front Plant Sci 2022  13  912637
Combining GWAS, Genome-Wide Domestication and a Transcriptomic Analysis Reveals the Loci and Natural Alleles of salt tolerance in Rice (<i>Oryza sativa</i> L.).
Dangol S., Nguyen N.K., Singh R., Chen Y., Wang J., Lee H.G., Hwang B.K., Jwa N.S.
Front Plant Sci 2021  12  710794
Mitogen-activated protein kinase OsMEK2 and OsMPK1 Signaling Is Required for Ferroptotic Cell Death in Rice-<i>Magnaporthe oryzae</i> Interactions.
Yang J., Ji L., Liu S., Jing P., Hu J., Jin D., Wang L., Xie G.
J. Exp. Bot. 2021   
The CaM1-Associated CCaMK-MKK1/6 cascade positively affects the lateral root growth through auxin signaling under salt stress in rice.
Viana V.E., Carlos da Maia L., Busanello C., Pegoraro C., Costa de Oliveira A.
Plant Biol (Stuttg) 2021  23 Suppl 1  100-112
When rice gets the chills: comparative transcriptome profiling at germination shows WRKY transcription factor responses.
Li N., Yang Z., Li J., Xie W., Qin X., Kang Y., Zhang Q., Li X., Xiao J., Ma H., Wang S.
Rice (N Y) 2021  14(1)  39
Two VQ Proteins are Substrates of the OsMPKK6-OsMPK4 Cascade in Rice Defense Against Bacterial Blight.
Wang D., Wang H., Liu Q., Tu R., Zhou X., Zhang Y., Wu W., Yu P., Chen D., Zhan X., Cao L., Cheng S., Shen X.
Plant Cell Rep. 2021  40(5)  835-850
Reduction of OsMPK6 activity by a R89K mutation induces cell death and bacterial blight resistance in rice.
Chen J., Wang L., Yuan M.
Int J Mol Sci 2021  22(4) 
Update on the Roles of Rice MAPK Cascades.
Jing X.Q., Li W.Q., Zhou M.R., Shi P.T., Zhang R., Shalmani A., Muhammad I., Wang G.F., Liu W.T., Chen K.M.
Rice (N Y) 2021  14(1)  100
Rice Carbohydrate-Binding Malectin-Like Protein, OsCBM1, Contributes to Drought-Stress Tolerance by Participating in NADPH oxidase-Mediated ROS Production.
Nanda S., Wan P.J., Yuan S.Y., Lai F.X., Wang W.X., Fu Q.
Int J Mol Sci 2018  19(12) 
Differential Responses of <i>OsMPK</i>s in IR56 Rice to Two BPH Populations of Different Virulence Levels.
Jalmi S.K., Sinha A.K.
Sci Rep 2016  6  37974
Functional Involvement of a Mitogen Activated Protein Kinase Module, OsMKK3-OsMPK7-OsWRK30 in Mediating Resistance against Xanthomonas oryzae in Rice.
Mohanta T.K., Mohanta N., Parida P., Bae H.
Biol Proced Online 2015  17  13
Mitogen Activated Protein Kinase (MPK) Interacts With Auxin Influx Carrier (OsAux/LAX1) Involved in Auxin Signaling in Plant.
Wang F., Jing W., Zhang W.
Plant Sci. 2014  227  181-9
The mitogen-activated protein kinase cascade MKK1-MPK4 mediates salt signaling in rice.
Chujo T., Miyamoto K., Ogawa S., Masuda Y., Shimizu T., Kishi-Kaboshi M., Takahashi A., Nishizawa Y., Minami E., Nojiri H., Yamane H., Okada K.
PLoS ONE 2014  9(6)  e98737
Overexpression of phosphomimic mutated OsWRKY53 leads to enhanced blast resistance in rice.
Park H.L., Lee S.W., Jung K.H., Hahn T.R., Cho M.H.
Phytochemistry 2013  96  57-71
Transcriptomic analysis of UV-treated rice leaves reveals UV-induced phytoalexin biosynthetic pathways and their regulatory networks in rice.
Xie G., Kato H., Imai R.
Biochem. J. 2012  443(1)  95-102
Biochemical identification of the OsMKK6-OsMPK3 signalling pathway for chilling stress tolerance in rice1.
Campos-Soriano L., García-Martínez J., Segundo B.S.
Mol. Plant Pathol. 2012  13(6)  579-92
The arbuscular mycorrhizal symbiosis promotes the systemic induction of regulatory defence-related genes in rice leaves and confers resistance to pathogen infection.
Shen X., Liu H., Yuan B., Li X., Xu C., Wang S.
Plant Cell Environ. 2011  34(2)  179-91
OsEDR1 negatively regulates rice bacterial resistance via activation of ethylene biosynthesis.
Shen X,Yuan B,Liu H,Li X,Xu C,Wang S
Plant J. 2010  64(1)  86-99
Opposite functions of a rice mitogen-activated protein kinase in the process of resistance against Xanthomonas oryzae.
Kishi-Kaboshi M., Okada K., Kurimoto L., Murakami S., Umezawa T., Shibuya N., Yamane H., Miyao A., Takatsuji H., Takahashi A., Hirochika H.
Plant Journal 2010  63(4)  599-612
A rice fungal MAMP-responsive MAPK cascade regulates metabolic flow to antimicrobial metabolite synthesis.
Xie G., Kato H., Sasaki K., Imai R.
FEBS Lett. 2009  583(17)  2734-8
A cold-induced thioredoxin h of rice, OsTrx23, negatively regulates kinase activities of OsMPK3 and OsMPK6 in vitro.
Yuan,B., Shen,X., Li,X., Xu,C. and Wang,S.
Planta. 2007  226(4)  953-960
Mitogen-activated protein kinase OsMPK6 negatively regulates rice disease resistance to bacterial pathogens
TextPresso Search Search textpresso for MPK6 ( Recent references may be retrievable, but without any warranty )
DB Reference
Gramene ID -
Gene Ontology response to cold( GO:0009409 )
MAP kinase activity( GO:0004707 )
ATP binding( GO:0005524 )
nucleus( GO:0005634 )
cytoplasm( GO:0005737 )
response to UV( GO:0009411 )
salicylic acid mediated signaling pathway( GO:0009863 )
hyperosmotic response( GO:0006972 )
auxin mediated signaling pathway( GO:0009734 )
defense response to bacterium( GO:0042742 )
response to hydrogen peroxide( GO:0042542 )
response to salicylic acid stimulus( GO:0009751 )
response to wounding( GO:0009611 )
defense response to insect( GO:0002213 )
hypotonic salinity response( GO:0042539 )
seed development( GO:0048316 )
response to water deprivation( GO:0009414 )
jasmonic acid mediated signaling pathway( GO:0009867 )
response to molecule of fungal origin( GO:0002238 )
response to molecule of bacterial origin( GO:0002237 )
response to light stimulus( GO:0009416 )
negative regulation of defense response( GO:0031348 )
negative regulation of programmed cell death( GO:0043069 )
response to abscisic acid stimulus( GO:0009737 )
jasmonic acid and ethylene-dependent systemic resistance( GO:0009861 )
MAPKKK cascade( GO:0000165 )
response to fungus( GO:0009620 )
response to indolebutyric acid stimulus( GO:0080026 )
defense response to fungus( GO:0050832 )
response to salt stress( GO:0009651 )
cortical microtubule organization( GO:0043622 )
Trait Ontology UV light sensitivity( TO:0000160 )
blast disease( TO:0000074 )
salt tolerance( TO:0006001 )
auxin sensitivity( TO:0000163 )
bacterial blight disease resistance( TO:0000175 )
stem borer resistance( TO:0000454 )
jasmonic acid content( TO:0002668 )
cold tolerance( TO:0000303 )
yield trait( TO:0000371 )
1000-seed weight( TO:0000382 )
seed set percent( TO:0000455 )
filled grain number( TO:0000447 )
grain number( TO:0002759 )
panicle length( TO:0000040 )
panicle number( TO:0000152 )
plant height( TO:0000207 )
hydrogen peroxide content( TO:0000605 )
light sensitivity( TO:0000075 )
mimic response( TO:0000063 )
drought tolerance( TO:0000276 )
Plant Ontology seed development stage( PO:0001170 )
leaf( PO:0025034 )
leaf sheath( PO:0020104 )
root( PO:0009005 )
Related Strains
Phenotype images
Last updated
Aug 14, 2023