NBRP Medaka

Medaka Strain
in Publications

	References
	Lectures of a conference

fli::GFP

Strain information
Strain ID	TG1206
Strain Name	fli::GFP
Strain Type	Transgenics
Characteristics	Endothelial progenitors of the Cuvier’s ducts can be first observed on the surface of the medaka embryo's yolk at around st.18 using the fli::GFP transgenic fish. The forming Cuvier's ducts are initially observed at around st.20. At st.25, EGFP fluorescence can also be detected in the heart located anteriorly of the head.
Journal	3 Hits. PMID: 35121372 [ RRC reference ] Kimura A, Kamimura K, Ohkoshi-Yamada M, Shinagawa-Kobayashi Y, Goto R, Owaki T, Oda C, Shibata O, Morita S, Sakai N, Abe H, Yokoo T, Sakamaki A, Kamimura H, Terai S. Effects of a novel selective PPARα modulator, statin, sodium-glucose cotransporter 2 inhibitor, and combinatorial therapy on the liver and vasculature of medaka nonalcoholic steatohepatitis model. Biochem Biophys Res Commun 2022/03/12.596.76-82. PMID: 31263118 [ RRC reference ] Mittal N, Yoon SH, Enomoto H, Hiroshi M, Shimizu A, Kawakami A, Fujita M, Watanabe H, Fukuda K, Makino S. Versican is crucial for the initiation of cardiovascular lumen development in medaka (Oryzias latipes). Sci Rep 2019/07/01.9(1).9475. PMID: 29331379 [ RRC reference ] Shinagawa-Kobayashi Y, Kamimura K, Goto R, Ogawa K, Inoue R, Yokoo T, Sakai N, Nagoya T, Sakamaki A, Abe S, Sugitani S, Yanagi M, Fujisawa K, Nozawa Y, Koyama N, Nishina H, Furutani-Seiki M, Sakaida I, Terai S. Effect of histidine on sorafenib-induced vascular damage: Analysis using novel medaka fish model. Biochem Biophys Res Commun 2018/02/05.496(2).556-561.
Special affairs　[Address]	■ The RECIPIENT shall refer the following publication in any PUBLICATIONS. (Name of the Publication: SHINAGAWA-KOBAYASHI, Yoko, et al. Effect of histidine on sorafenib-induced vascular damage: Analysis using novel medaka fish model. Biochemical and biophysical research communications, 2018, 496.2: 556-561.)
Category	Transgenic strains
Organization	National Institute for Basic Biology
Live	○
Deposited by	Yamaguchi University
Order
Image	Transgene map_fli GFP Approximately 15 kb of the putative fli1 promoter was ligated to EGFP.
Image	TG1206_fli GFP_embryo Strong EGFP expression can be observed in the Cuvier’s duct at st.26.