p53(E241x)

Strain information
Strain ID MT894
Strain Name p53(E241x)
Strain Type Mutants
Characteristics predisposed to cancer

You can confirm the mutation using the amplification primers:
5’- TGTTACATTTTATAGCTGTGGAGCA-3’ (forward)
5’- GGCTGAAAACAGCACAACC-3’ (reverse)


Sequence with Reverse primer:
E241X: TCTGGAAACC (G>T) AGTAAGTTTA
Journal
  •    6  Hits.
    • Tu TY, Hong CY, Sasado T, Kashiwada S, Chen PJ. Early life exposure to a rodent carcinogen propiconazole fungicide induces oxidative stress and hepatocarcinogenesis in medaka fish. Aquat. Toxicol. 2016/01.170.52-61.

      Hirako A, Takeoka Y, Furukawa S, Sugiyama A. Effects of methotrexate exposure on medaka (<i>Oryzias latipes</i>) testes. J Toxicol Pathol 2017/10.30(4).283-289.

      Schartl M, Wilde B, Laisney JA, Taniguchi Y, Takeda S, Meierjohann S. A mutated EGFR is sufficient to induce malignant melanoma with genetic background-dependent histopathologies. J. Invest. Dermatol. 2010/01.130(1).249-58.

      Isoe Y, Okuyama T, Taniguchi Y, Kubo T, Takeuchi H. p53 Mutation suppresses adult neurogenesis in medaka fish (Oryzias latipes). Biochem. Biophys. Res. Commun. 2012/07/13.423(4).627-31.

      Ueno T, Suzuki H, Hiraishi M, Amano H, Fukuyama H, Sugimoto N. In vivo Magnetic Resonance Microscopy and Hypothermic Anaesthesia of a Disease Model in Medaka. Sci Rep 2016/06/02.6.27188.

      Taniguchi Y, Takeda S, Furutani-Seiki M, Kamei Y, Todo T, Sasado T, Deguchi T, Kondoh H, Mudde J, Yamazoe M, Hidaka M, Mitani H, Toyoda A, Sakaki Y, Plasterk RH, Cuppen E. Generation of medaka gene knockout models by target-selected mutagenesis. Genome Biol. 2006.7(12).R116.
Special affairs [Address] ■The RECIPIENT shall refer the following publication in any PUBLICATIONS.
(Name of the Publication: Taniguchi Y, Takeda S, Furutani-Seiki M, Kamei Y, Todo T, Sasado T, Deguchi T, Kondoh H, Mudde J, Yamazoe M, Hidaka M, Mitani H, Toyoda A, Sakaki Y, Plasterk RH and Cuppen E. (2006) Generation of medaka gene knockout models by target-selected mutagenesis. Genome Biol. 7(12):R116 )
Category Mutants created by TILLING
Organization National Institute for Basic Biology
Live in NIBB
Frozen sperm in NIBB
Deposited by Kyoto University
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