Strain information
Strain ID MT443
Strain Name yanagi^j6-29C
Strain Type Mutants
Symbol yan^j6-29C
Characteristics Abnormal lateral line; abnormal PGC distribution
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Special affairs [Address] ■ The RECIPIENT shall refer the following publication in any PUBLICATIONS.
(Name of the Publication: Sasado T, Yasuoka A, Abe K, Mitani H, Furutani-Seiki M, Tanaka M, Kondoh H. Distinct contributions of CXCR4b and CXCR7/RDC1 receptor systems in regulation of PGC migration revealed by medaka mutants kazura and yanagi. Dev Biol. 2008/08/15.320(2).328-39. Liedtke D, Erhard I, Abe K, Furutani-Seiki M, Kondoh H, Schartl M. Xmrk-induced melanoma progression is affected by Sdf1 signals through Cxcr7. Pigment Cell Melanoma Res. 2014/03.27(2).221-33.)
Category Mutant of embryogeneses
Organization National Institute for Basic Biology
Frozen sperm in NIBB
Deposited by ERATO Kondoh Differentiation Signaling Project, Japan Science and Technology Agency
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ERATO Kondoh Project - 1
Submitter Takao Sasado   Observed in  
Attribute   Value  

Comment PGCs formed tight bilateral clumps in wild-type embryos at st. 27. In yanagi (yanj6-29C) mutant embryos, however, PGCs did not coalesce but were loosely aligned in bilateral rows in the region more anterior than normal PGC clusters. The positioning of lateral line organs were also affected in this mutant embryos (Yasuoka et al.,MOD121:729-738). Homozygotes of yan were viable and fertile.  
○not specified 
Image View Orientation
○side view (lateral) 
○animal pole 
○vegetal pole 
○not specified 
○anterior to left 
●anterior to top 
○anterior to right 
○dorsal to top 
○dorsal to right 
○not specified 
Caption / Comment
Whole-mount in situ hybridization using the olvas probe at st. 27. In the wild-type embryo (top), PGCs are clustered at the ventrolateral regions of the trunk (indicated by black arrowheads) at the axial level where the posterior trunk detach from the yolk. In the mutant embryo (bottom), PGCs are dispersed along the bilateral lines (broken lines) anterior to the sites of normal PGC clustering. White arrowheads indicate the pigment cells.