|Characteristics||With the TALEN technology, 25 bp in exon 1 of esr1 (estrogen receptor 1) gene has deleted. This mutant did not show any significant defects in the gonadal development or sexual differentiation. Background of this mutant is Cab strain.|
|Special affairs [Address]||
■ The RECIPIENT shall refer the following publication in any PUBLICATIONS.
(Name of the Publication: TOHYAMA, Saki, et al. Establishment of estrogen receptor 1 (ESR1)‐knockout medaka: ESR1 is dispensable for sexual development and reproduction in medaka, Oryzias latipes. Development, growth & differentiation, 2017, 59.6: 552-561.)
■ The RECIPIENT shall give proper credit to the DEVELOPER in any publications reporting results of research using any derivatives developed from the BIOLOGICAL MATERIALS (hereinafter referred to as “the DERIVATIVES”), and shall procure other institutionsto which the DERIVATIVES are provided (including when provided through the NBRP) to do the same.
|Category||Mutants created by genome editing|
|Organization||National Institute for Basic Biology|
|Frozen sperm in NIBB||○|
|Deposited by||Wakayama Medical University|
|Document (PDF)||Genotyping protocol_MT1198|