Hd-rR-p53(y186x)

Strain information
Strain ID MT1166
Strain Name Hd-rR-p53(y186x)
Strain Type Mutants
Characteristics This strain is derived by p53(y186x)(MT893, Cab background) created through TILLING and crossed with Hd-rR more than 7 times. Phenotypes are different in Homozygous (Y186X/Y186X) mutants from the original Cab mutant fish p53(y186x) (MT893), for example there is no tumor for their whole life. As for the background is close to Hd-rR, this mutant shows high-reproducible phenotype to several stresses.
Notes Please note that we will use OK-Cab (MT830) for artificially insemination with frozen sperm of this strain.
Journal
  •    1  Hits.
    • Yasuda T, Oda S, Li Z, Kimori Y, Kamei Y, Ishikawa T, Todo T, Mitani H. Gamma-ray irradiation promotes premature meiosis of spontaneously differentiating testis-ova in the testis of p53-deficient medaka (Oryzias latipes). Cell Death Dis 2012/10/04.3.e395.
Special affairs [Address] ■ The RECIPIENT shall refer the following publication in any PUBLICATIONS. (Name of the Publication: The paper is unpublished now, so detail information is notified after the paper is published.)
■ The RECIPIENT shall give proper credit to the DEVELOPER in any publications reporting results of research using any derivatives developed from the BIOLOGICAL MATERIALS (hereinafter referred to as “the DERIVATIVES”), and shall procure other institutionsto which the DERIVATIVES are provided (including when provided through the NBRP) to do the same.
Category Mutants created by TILLING
Organization National Institute for Basic Biology
Frozen sperm in NIBB
Deposited by The University of Tokyo
Order Request
Document (PDF) Genotyping protocol_MT893


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