|Characteristics||This strain expresses HRAS12V gene in the presence of Cre recombinase. Transgene: 3354b Medaka tyrosinase promoter was ligated to loxP-EGFP-loxP-HRASG12V fusion gene in pTIS10-d-loxGFP-OlBMP4 (constructed by Shimizu, A).|
|Special affairs [Address]||
■The RECIPIENT shall refer the following publication in any PUBLICATIONS.
(Name of the Publication: Establishment of HRASG12V transgenic medaka as a stable tumor model for in vivo screening of anticancer drugs. PLoS ONE 8(1): e54424)
■The RECIPIENT shall include the name(s) of following researcher(s) as co-authors in the first PUBLICATION. (Name(s) of researcher(s): Yuriko Matsuzaki, Hideyuki Saya)
■The RECIPIENT shall give proper credit to the DEVELOPER in any publications reporting results of research using any derivatives developed from the BIOLOGICAL MATERIALS (hereinafter referred to as “the DERIVATIVES”), and shall procure other institutionsto which the DERIVATIVES are provided (including when provided through the NBRP) to do the same.
|Organization||National Institute for Basic Biology|
|Frozen sperm in NIBB||○|
|Deposited by||Keio University|
F1 adult fish obtained from cross with hsp-Cre strain. Penetrance is 55 % at 6 mpf.