TG840_Tg(EF-1alpha-A-Pkd2deltaC-EGFP) Histological analysis (HE staining) of adult medaka at aged seven months in the heterozygote of EF-1α-A-Pkd2ΔC-EGFP no.12 strain. A) C) A few cysts in the right kidney can be detected. Asterisk shows an ureter, which is equivalent to an ureter of human.(A;40x, C;100x)) B) A few cysts in the left kidney can be detected. (40x) D) No cyst can be detected in a control of adult medaka. (40x)
The homozygous transgenic (EF-1alpha-A-Pkd2deltaC-EGFP) medaka at 5 months after hatching has some kidney cysts in hemotoxyline-eosin-stained section (original magnification x40). Arrows indicate cysts. * indicate uretea.