Strain information
Strain ID TG840
Strain Name Tg(EF-1alpha-A-Pkd2deltaC-EGFP)
Strain Type Transgenics
Characteristics Transgene: Medaka EF-1α-A promoter, Medaka polycystic kidney disease 2 (Pkd2) gene, EGFP.
Category Transgenic strains
Organization National Institute for Basic Biology
Frozen sperm in NIBB
Deposited by Hokkaido University and Nagoya University
Order Request

Histological analysis (HE staining) of adult medaka at aged seven months in the heterozygote of EF-1α-A-Pkd2ΔC-EGFP no.12 strain.
A) C) A few cysts in the right kidney can be detected. Asterisk shows an ureter, which is equivalent to an ureter of human.(A;40x, C;100x))
B) A few cysts in the left kidney can be detected. (40x)
D) No cyst can be detected in a control of adult medaka. (40x)

The homozygous transgenic (EF-1alpha-A-Pkd2deltaC-EGFP) medaka at 5 months after hatching has some kidney cysts in hemotoxyline-eosin-stained section (original magnification x40). Arrows indicate cysts. * indicate uretea.

TG840_Tg(EF-1alpha-A-Pkd2deltaC-EGFP)_transgene map