|Characteristics||ESCO2^R80S/R80S homozygous mutants exhibit developmental delay and die before hatching. Head deformities (particularly brain and eye malformation) and somite malformation are observed in homozygous mutants. In chromosomal analysis, mutants also show a significant increase in the chromosomal abnormalities, premature centromere separation.|
|Special affairs [Address]||
■The RECIPIENT shall refer the following publication in any PUBLICATIONS.
(Morita, et al. Develop. Growth Differ. 54 :588-604, 2012)
|Category||Mutants created by TILLING|
|Organization||National Institute for Basic Biology|
|Frozen sperm in NIBB||○|
|Deposited by||Osaka Medical Center and Research Institute for Maternal and Child Health|
Head deformities (particularly brain and eye malformation, arrow head) in homozygous mutant embryos at 2 dpf (days post-fertilization).