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tbx6(del7)
| Strain information | |
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| Strain ID | MT1246 |
| Strain Name | tbx6(del7) |
| Strain Type | Mutants |
| Characteristics | A 7 bp was deleted in exon 2 of tbx6 gene by the TALEN genome editing system. This mutation is expected to introduce frame-shift mutation, resulting in truncation of the C-terminus of the tbx6 protein, including the T-box domain. The somite boundaries of homozygous mutant are not clearly observed during somitogenesis. The tbx6 mutants of zebrafish were identified as fused somites (fss). |
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| Special affairs [Address] | ■ The RECIPIENT should make a prior contact with Keiji Inohaya (kinohaya@bio.titech.ac.jp), and arrange for collaborative research or offer conditions with a written form of consent. Then, the RECIPIENT shall make a request for this strain to NBRP Medaka at NIBB. |
| Category | Mutants created by genome editing |
| Organization | National Institute for Basic Biology |
| Frozen sperm in NIBB | ○ |
| Deposited by | Tokyo Institute of Technology |
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| Image |
Fig_MT1246 The somite boundaries of homozygous mutant are not clearly observed during somitogenesis. Day-2 embryos (Stage 23). Dorsal views. |
| Document (PDF) | Genotyping protocol_MT1246 |
