NBRP Medaka

Medaka Strain
in Publications

	References
	Lectures of a conference

FLFII

Strain information
Strain ID	MT109
Strain Name	FLFII
Strain Type	Mutants
Characteristics	Dimorphism in body color. Female is white (b/b, X^r/X^r ) and leucophore free (lf/lf), and male is orange-red (b/b, X^r/Y^R) and wild type (lf/+) for the leucophore phenotype. Dimorphism also observed in PCR marker, SL1, with one band in females and two bands in males.
Notes	The RECIPIENT shall use the BIOLOGICAL MATERIALS only for the purpose of research. Please note that we will use OK-Cab (MT830) for artificially insemination with frozen sperm of this strain.
Journal	16 Hits. PMID: 33550114 [ RRC reference ] Ussery EJ, Nielsen KM, Simmons D, Pandelides Z, Mansfield C, Holdway D. An 'omics approach to investigate the growth effects of environmentally relevant concentrations of guanylurea exposure on Japanese medaka (Oryzias latipes). Aquat Toxicol 2021/01/29.232.105761. PMID: 35352155 [ RRC reference ] Liu L, Hobohm L, Bredendiek F, Froschauer A, Zierau O, Parr MK, Keiler AM. Medaka embryos as a model for metabolism of anabolic steroids. Arch Toxicol 2022/07/01.96(7).1963-1974. PMID: 23936463 [ RRC reference ] Shiraishi E, Hosseini H, Kang DK, Kitano T, Akiyama H. Nanosecond pulsed electric field suppresses development of eyes and germ cells through blocking synthesis of retinoic acid in Medaka (Oryzias latipes). PLoS One 2013/01/01.8(8).e70670. PMID: 20653000 [ RRC reference ] Hayashi Y, Kobira H, Yamaguchi T, Shiraishi E, Yazawa T, Hirai T, Kamei Y, Kitano T. High temperature causes masculinization of genetically female medaka by elevation of cortisol. Mol Reprod Dev 2010/08/01.77(8).679-86. PMID: 33133021 [ RRC reference ] Kawabe T, Kariya H, Hara S, Shirozu T, Shiraishi E, Mukai K, Yazawa T, Inoue S, Kitano T. Transcriptional Regulation of Müllerian Inhibiting Substance (MIS) and Establishment of a Gonadal Somatic Cell Line Using <i>mis-GFP</i> Transgenic Medaka (<i>Oryzias latipes</i>). Front Endocrinol (Lausanne) 2020/01/01.11.578885. PMID: 32072671 [ RRC reference ] Anderson JC, Beyger L, Guchardi J, Holdway DA. The Effects of 17α-Ethinylestradiol on the Heart Rate of Embryonic Japanese Medaka (Oryzias latipes). Environ Toxicol Chem 2020/04/01.39(4).904-912. PMID: 30835871 [ RRC reference ] Ussery E, Bridges KN, Pandelides Z, Kirkwood AE, Guchardi J, Holdway D. Developmental and Full-Life Cycle Exposures to Guanylurea and Guanylurea-Metformin Mixtures Results in Adverse Effects on Japanese Medaka (Oryzias latipes). Environ Toxicol Chem 2019/05/01.38(5).1023-1028. PMID: 26428616 [ RRC reference ] Pfennig F, Standke A, Gutzeit HO. The role of Amh signaling in teleost fish--Multiple functions not restricted to the gonads. Gen Comp Endocrinol 2015/11/01.223.87-107. PMID: 26148066 [ RRC reference ] Froschauer A, Kube L, Kegler A, Rieger C, Gutzeit HO. Tunable Protein Stabilization In Vivo Mediated by Shield-1 in Transgenic Medaka. PLoS One 2015/01/01.10(7).e0131252. PMID: 24877625 [ RRC reference ] Murozumi N, Nakashima R, Hirai T, Kamei Y, Ishikawa-Fujiwara T, Todo T, Kitano T. Loss of follicle-stimulating hormone receptor function causes masculinization and suppression of ovarian development in genetically female medaka. Endocrinology 2014/08/01.155(8).3136-45. PMID: 23139203 [ RRC reference ] Froschauer A, Khatun MM, Sprott D, Franz A, Rieger C, Pfennig F, Gutzeit HO. oct4-EGFP reporter gene expression marks the stem cells in embryonic development and in adult gonads of transgenic medaka. Mol Reprod Dev 2013/01/01.80(1).48-58. PMID: 21533666 [ RRC reference ] Froschauer A, Sprott D, Gerwien F, Henker Y, Rudolph F, Pfennig F, Gutzeit HO. Effective generation of transgenic reporter and gene trap lines of the medaka (Oryzias latipes) using the Ac/Ds transposon system. Transgenic Res 2012/02/01.21(1).149-62. PMID: 18312429 [ RRC reference ] Pfennig F, Kind B, Zieschang F, Busch M, Gutzeit HO. Tert expression and telomerase activity in gonads and somatic cells of the Japanese medaka (Oryzias latipes). Dev Growth Differ 2008/03/01.50(3).131-41. PMID: 15760335 [ RRC reference ] Lynn Lamoreux M, Kelsh RN, Wakamatsu Y, Ozato K. Pigment pattern formation in the medaka embryo. Pigment Cell Res 2005/04/01.18(2).64-73. PMID: 15559293 [ RRC reference ] Balch GC, Shami K, Wilson PJ, Wakamatsu Y, Metcalfe CD. Feminization of female leukophore-free strain of Japanese medaka (Oryzias latipes) exposed to 17beta-estradiol. Environ Toxicol Chem 2004/11/01.23(11).2763-8. PMID: [ RRC reference ] Wakamatsu, Y., Inoue, C., Hayashi, H., Mishima, N., Sakaizumi, M., and Ozato, K. Establishment of new medaka (Oryzias latipes) stocks carrying genotypic sex markers. Environ Sci 2003/01/01.10(5).291-302.
Special affairs　[Address]	■The RECIPIENT shall refer the following publication in any PUBLICATIONS and/or any presentations. (Name of the Publication: Wakamatsu, Y., Inoue, C., Hayashi, H., Mishima, N., Sakaizumi, M., and Ozato, K. Establishment of new medaka (Oryzias latipes) stocks carrying genotypic sex markers. Environ. Sci. 10(5), 291-302, 2003.）
Category	Spontaneous mutant strains
Organization	National Institute for Basic Biology
Frozen sperm in NIBB	○
Deposited by	Nagoya university
Order
Image	MT109_FLFII