As a result of TILLING library screening, single base substitution in exon 13 of msh2 gene was identified. This mutation generate a stop codon at 729th leucine (L729X), which result in truncation of the C-terminus of Msh2 protein. There are no appearent characteristics.
■ The RECIPIENT shall refer the following publication in any PUBLICATIONS. (Name of the Publication : Otozai S, Ishikawa-Fujiwara T, Oda S, Kamei Y, Ryo H, Sato A, Nomura T, Mitani H, Tsujimura T, Inohara H, Todo T. p53-Dependent suppression of genome instability in germ cells. Mutat Res. 2014 Feb;760:24-32. doi: 10.1016/j.mrfmmm.2013.12.004.) ■ The RECIPIENT shall give proper credit to the DEVELOPER in any publications reporting results of research using any derivatives developed from the BIOLOGICAL MATERIALS (hereinafter referred to as “the DERIVATIVES”), and shall procure other institutionsto which the DERIVATIVES are provided (including when provided through the NBRP) to do the same.
