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otafuku^jF82-2C
| Strain information | |
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| Strain ID | MT413 |
| Strain Name | otafuku^jF82-2C |
| Strain Type | Mutants |
| Symbol | ota^jF82-2C |
| Characteristics | Abnormal forebrain morphogenesis; abnormal PGC distribution |
Journal
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| Special affairs [Address] | ■The RECIPIENT shall include the name(s) of following researcher(s) as co-authors in the first PUBLICATION. (Name(s) of researcher(s): Makoto Furutani-Seiki and Hisato Kondoh) |
| Category | Mutant of embryogeneses |
| Organization | National Institute for Basic Biology |
| Frozen sperm in NIBB | ○ |
| Deposited by | ERATO Kondoh Differentiation Signaling Project, Japan Science and Technology Agency |
| Order |
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| ERATO Kondoh Project - 1 | |||||||||||||||||||||||||||
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| Submitter | Takao Sasado | Observed in | |||||||||||||||||||||||||
| Attribute | Value | ||||||||||||||||||||||||||
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Phenotype
Manifestation |
recessive
penetrance_complete expressivity_complete |
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| Note | |||||||||||||||||||||||||||
| Comment | PGCs formed tight bilateral clumps in wild-type embryos at st. 27. In otafuku (otajf82-2C) mutant embryos, however, PGCs did not coalesce but were loosely aligned in bilateral rows in the region more anterior than normal PGC clusters. The homozygous smg mutation caused lethality and other morphogenetic defects such as large heads, multiple otic vesicles, and inferior trunk structures. | ||||||||||||||||||||||||||
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