MR(del2)

Strain information
Strain ID MT1050
Strain Name MR(del2)
Strain Type Mutants
Characteristics Using TALEN technology, a constitutive mineralocorticoid receptor (MR)-KO medaka was generated as a mutant with a frameshift at the amino acid #42. Hyper- and hypo-osmoregulation were normal in homozygous mutant medaka. However, homozygous mutants failed to track moving dots despite having an increase in acceleration of swimming.
Journal
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Category Mutants created by genome editing
Organization National Institute for Basic Biology
Frozen sperm in NIBB
Deposited by Okayama University
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Image

Abnormal responses to visual motion stimuli in MR-KO medaka
Distance to the stimulus dot from the head and trajectory of a representative fish during stimulus presentation.
Document (PDF) MT1050_Genotyping protocol


/medaka