NBRP Medaka

Medaka Strain
in Publications

	References
	Lectures of a conference

yanagi^j6-29C

Strain information
Strain ID	MT443
Strain Name	yanagi^j6-29C
Strain Type	Mutants
Symbol	yan^j6-29C
Characteristics	Abnormal lateral line; abnormal PGC distribution
Journal	4 Hits. PMID: 28087632 [ RRC reference ] Seleit A, Krämer I, Ambrosio E, Dross N, Engel U, Centanin L. Sequential organogenesis sets two parallel sensory lines in medaka. Development 2017/02/15.144(4).687-697. PMID: 24279354 [ RRC reference ] Liedtke D, Erhard I, Abe K, Furutani-Seiki M, Kondoh H, Schartl M. Xmrk-induced melanoma progression is affected by Sdf1 signals through Cxcr7. Pigment Cell Melanoma Res 2014/03/01.27(2).221-33. PMID: 24385628 [ RRC reference ] Okuyama T, Yokoi S, Abe H, Isoe Y, Suehiro Y, Imada H, Tanaka M, Kawasaki T, Yuba S, Taniguchi Y, Kamei Y, Okubo K, Shimada A, Naruse K, Takeda H, Oka Y, Kubo T, Takeuchi H. A neural mechanism underlying mating preferences for familiar individuals in medaka fish. Science 2014/01/03.343(6166).91-4. PMID: 18602095 [ RRC reference ] Sasado T, Yasuoka A, Abe K, Mitani H, Furutani-Seiki M, Tanaka M, Kondoh H. Distinct contributions of CXCR4b and CXCR7/RDC1 receptor systems in regulation of PGC migration revealed by medaka mutants kazura and yanagi. Dev Biol 2008/08/15.320(2).328-39.
Special affairs　[Address]	■ The RECIPIENT shall refer the following publication in any PUBLICATIONS. (Name of the Publication: Sasado T, Yasuoka A, Abe K, Mitani H, Furutani-Seiki M, Tanaka M, Kondoh H. Distinct contributions of CXCR4b and CXCR7/RDC1 receptor systems in regulation of PGC migration revealed by medaka mutants kazura and yanagi. Dev Biol. 2008/08/15.320(2).328-39. Liedtke D, Erhard I, Abe K, Furutani-Seiki M, Kondoh H, Schartl M. Xmrk-induced melanoma progression is affected by Sdf1 signals through Cxcr7. Pigment Cell Melanoma Res. 2014/03.27(2).221-33.)
Category	Mutant of embryogeneses
Organization	National Institute for Basic Biology
Frozen sperm in NIBB	○
Deposited by	ERATO Kondoh Differentiation Signaling Project, Japan Science and Technology Agency
Order

ERATO Kondoh Project - 1

Submitter

Takao Sasado

Observed in

Attribute

Value

Phenotype
Manifestation

recessive

penetrance_complete
expressivity_complete

Note

Comment

PGCs formed tight bilateral clumps in wild-type embryos at st. 27. In yanagi (yanj6-29C) mutant embryos, however, PGCs did not coalesce but were loosely aligned in bilateral rows in the region more anterior than normal PGC clusters. The positioning of lateral line organs were also affected in this mutant embryos (Yasuoka et al.,MOD121:729-738). Homozygotes of yan were viable and fertile.

Image

Preparation
○live ●whole-mount ○LM-section ○EM-section ○not specified
Image View		Orientation
○side view (lateral) ●dorsal ○ventral ○frontal ○animal pole ○vegetal pole ○transverse ○sagittal ○parasagittal ○not specified		○anterior to left ●anterior to top ○anterior to right ○dorsal to top ○dorsal to right ○oblique ○not specified
Caption / Comment
Whole-mount in situ hybridization using the olvas probe at st. 27. In the wild-type embryo (top), PGCs are clustered at the ventrolateral regions of the trunk (indicated by black arrowheads) at the axial level where the posterior trunk detach from the yolk. In the mutant embryo (bottom), PGCs are dispersed along the bilateral lines (broken lines) anterior to the sites of normal PGC clustering. White arrowheads indicate the pigment cells.