plxnD1(del1)

Strain information
Strain ID MT1331
Strain Name plxnD1(del1)
Strain Type Mutants
Characteristics A 1 bp was deleted in exon 1 of plexin D1 (plxnD1) gene by the TALEN genome editing system. This mutation is expected to introduce frame-shift mutation and anticipated to produce dysfunction in the plxnD1 protein. The homozygous mutants show an abnormal pattering of intersegmental vessel.
Journal
Special affairs [Address] ■ The RECIPIENT should make a prior contact with Keiji Inohaya (kinohaya@bio.titech.ac.jp), and arrange for collaborative research or offer conditions with a written form of consent. Then, the RECIPIENT shall make a request for this strain to NBRP Medaka at NIBB.
Category Mutants created by genome editing
Organization National Institute for Basic Biology
Frozen sperm in NIBB
Deposited by Tokyo Institute of Technology
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Image

MT1331_plxnD1(del1)
The plexinD1 mutant shows abnormal patterning of intersegmental vessels. Just hatched fli1-EGFP-positive larvae. Lateral views.
Document (PDF) Genotyping protocol_MT1331 plxnD1(del1)


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