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| NIG-RNAi Strains Detail |
| Request : Click the "Order" button to request for this stock |
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| Stock Detail (Last Update: November 2007_FlyBase version FB2007_11) |
| Stock ID |
11144R-3 |
| Symbol |
mGluRA |
Full Name |
metabotropic glutamate receptor |
| CG No |
CG11144 |
Old CG No |
CG11144 |
| Synonyms |
CAA67993.1_Dr, DmGluAR, DmGluRA, DmGlu-A, DmGluR[[A]], DmGluR, dmGluRA, CG11144, mGluR, DmGlu-RA, mGluRA, Glu-RA |
| Accession No (Link to NCBI) |
NM_079900.2 |
| Inserted Chr. |
lll |
| Insertional Mutation |
semi-lethal |
| Phenotype induced by Act5C-GAL4 at 28 degrees |
viable |
| Map Viewer |
|
Reference
[Please submit your publication]
|
Onur TS, Laitman A, Zhao H, Keyho R, Kim H, Wang J, Mair M, Wang H, Li L, Perez A, de Haro M, Wan YW, Allen G, Lu B, Al-Ramahi I, Liu Z, Botas J.<br> Downregulation of glial genes involved in synaptic function mitigates Huntington's disease pathogenesis.<br> Elife (2021) 10
[
PubMed ID = 33871358
]
[
RRC reference
]
|
| Comment |
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| Sequence (Last Update: July 10, 2007_NCBI RefSeq Release 24) |
| Primer Seq. 5' |
aaggcctacatggccggaccgCGTGATGGTTTTATCCTGGAG |
| Primer Seq. 3' |
aatctagaggtaccAGGCCGGTGATACTTGAGGAA |
| Predicted Fragment Size |
500 |
| IR fragment full Seq |
0001 CGTGATGGTT TTATCCTGGA GTCGAGTAGT AGACTTAAAA AGTCCTAGTA ACACACATAC
0061 TCAGGATTCA GTGTCTGTTT CTCTGCCTGG CGACATTATA CTTGGTGGGC TATTTCCGGT
0121 CCATGAAAAA GGTGAAGGTG CCCCTTGCGG ACCAAAAGTA TATAATAGGG GAGTTCAACG
0181 CCTGGAAGCA ATGCTGTATG CTATAGATCG TGTAAACAAT GACCCCAACA TACTTCCTGG
0241 AATTACGATA GGAGTCCATA TACTTGACAC CTGTTCAAGA GACACATATG CCCTCAATCA
0301 GTCGCTTCAA TTTGTCAGAG CATCCCTAAA CAATTTAGAC ACATCAGGAT ATGAGTGTGC
0361 AGATGGGTCA AGCCCGCAAC TAAGAAAAAA TGCTTCGTCA GGCCCAGTTT TTGGAGTTAT
0421 TGGCGGGTCC TACAGTTCAG TGTCCTTGCA AGTGGCCAAT TTGCTGCGTC TGTTTCATAT
0481 TCCTCAAGTA TCACCGGCCT |
| in silico PCR Fragment |
0001 CGTGATGGTT TTATCCTGGA GTCGAGTAGT AGACTTAAAA AGTCCTAGTA ACACACATAC
0061 TCAGGATTCA GTGTCTGTTT CTCTGCCTGG CGACATTATA CTTGGTGGGC TATTTCCGGT
0121 CCATGAAAAA GGTGAAGGTG CCCCTTGCGG ACCAAAAGTA TATAATAGGG GAGTTCAACG
0181 CCTGGAAGCA ATGCTGTATG CTATAGATCG TGTAAACAAT GACCCCAACA TACTTCCTGG
0241 AATTACGATA GGAGTCCATA TACTTGACAC CTGTTCAAGA GACACATATG CCCTCAATCA
0301 GTCGCTTCAA TTTGTCAGAG CATCCCTAAA CAATTTAGAC ACATCAGGAT ATGAGTGTGC
0361 AGATGGGTCA AGCCCGCAAC TAAGAAAAAA TGCTTCGTCA GGCCCAGTTT TTGGAGTTAT
0421 TGGCGGGTCC TACAGTTCAG TGTCCTTGCA AGTGGCCAAT TTGCTGCGTC TGTTTCATAT
0481 TCCTCAAGTA TCACCGGCCT |
| Assemble Data |
<PRE>
11144R-3.IR_full 1 CGTGATGGTTTTATCCTGGAGTCGAGTAGTAGACTTAAAAAGTCCTAGTAACACACATAC 60
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
11144R-3.in silico 1 CGTGATGGTTTTATCCTGGAGTCGAGTAGTAGACTTAAAAAGTCCTAGTAACACACATAC 60
11144R-3.IR_full 61 TCAGGATTCAGTGTCTGTTTCTCTGCCTGGCGACATTATACTTGGTGGGCTATTTCCGGT 120
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
11144R-3.in silico 61 TCAGGATTCAGTGTCTGTTTCTCTGCCTGGCGACATTATACTTGGTGGGCTATTTCCGGT 120
11144R-3.IR_full 121 CCATGAAAAAGGTGAAGGTGCCCCTTGCGGACCAAAAGTATATAATAGGGGAGTTCAACG 180
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
11144R-3.in silico 121 CCATGAAAAAGGTGAAGGTGCCCCTTGCGGACCAAAAGTATATAATAGGGGAGTTCAACG 180
11144R-3.IR_full 181 CCTGGAAGCAATGCTGTATGCTATAGATCGTGTAAACAATGACCCCAACATACTTCCTGG 240
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
11144R-3.in silico 181 CCTGGAAGCAATGCTGTATGCTATAGATCGTGTAAACAATGACCCCAACATACTTCCTGG 240
11144R-3.IR_full 241 AATTACGATAGGAGTCCATATACTTGACACCTGTTCAAGAGACACATATGCCCTCAATCA 300
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
11144R-3.in silico 241 AATTACGATAGGAGTCCATATACTTGACACCTGTTCAAGAGACACATATGCCCTCAATCA 300
11144R-3.IR_full 301 GTCGCTTCAATTTGTCAGAGCATCCCTAAACAATTTAGACACATCAGGATATGAGTGTGC 360
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
11144R-3.in silico 301 GTCGCTTCAATTTGTCAGAGCATCCCTAAACAATTTAGACACATCAGGATATGAGTGTGC 360
11144R-3.IR_full 361 AGATGGGTCAAGCCCGCAACTAAGAAAAAATGCTTCGTCAGGCCCAGTTTTTGGAGTTAT 420
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
11144R-3.in silico 361 AGATGGGTCAAGCCCGCAACTAAGAAAAAATGCTTCGTCAGGCCCAGTTTTTGGAGTTAT 420
11144R-3.IR_full 421 TGGCGGGTCCTACAGTTCAGTGTCCTTGCAAGTGGCCAATTTGCTGCGTCTGTTTCATAT 480
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
11144R-3.in silico 421 TGGCGGGTCCTACAGTTCAGTGTCCTTGCAAGTGGCCAATTTGCTGCGTCTGTTTCATAT 480
11144R-3.IR_full 481 TCCTCAAGTATCACCGGCCT 500
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11144R-3.in silico 481 TCCTCAAGTATCACCGGCCT 500
</PRE>
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| Off-target information (Last Update: November 4, 2007_NCBI RefSeq Release 26) |
Off-target search result
cv : coefficient of variation
(0 mm hits / total siRNA count)
mm : mismatch
|
| cv |
0mm |
1mm |
2mm |
3mm |
target transcript |
off target name |
| 100 |
482 |
0 |
0 |
0 |
NM_079900.2 |
CG11144-RA (Glu-RA), mRNA |
| 0 |
0 |
5 |
2 |
4 |
NM_139422.2 |
CG1017-RA (CG1017), mRNA |
| 0 |
0 |
5 |
2 |
3 |
NM_079692.2 |
CG4204-RA (Elongin-B), mRNA |
| 0 |
0 |
2 |
2 |
3 |
NM_078977.2 |
CG10897-RA, transcript variant A (tou), mRNA |
| 0 |
0 |
1 |
7 |
4 |
NM_132660.2 |
CG1716-RA (CG1716), mRNA |
| 0 |
0 |
1 |
3 |
3 |
NM_079894.3 |
CG11049-RA, transcript variant A (sv), mRNA |
| 0 |
0 |
1 |
3 |
3 |
NM_001014700.1 |
CG11049-RE, transcript variant E (sv), mRNA |
| 0 |
0 |
1 |
3 |
3 |
NM_001014701.1 |
CG11049-RD, transcript variant D (sv), mRNA |
| 0 |
0 |
1 |
3 |
3 |
NM_001014697.1 |
CG11049-RH, transcript variant H (sv), mRNA |
| 0 |
0 |
1 |
3 |
3 |
NM_166822.3 |
CG11049-RC, transcript variant C (sv), mRNA |
| 0 |
0 |
1 |
3 |
3 |
NM_001014699.1 |
CG11049-RF, transcript variant F (sv), mRNA |
| 0 |
0 |
1 |
3 |
3 |
NM_001014698.1 |
CG11049-RG, transcript variant G (sv), mRNA |
| 0 |
0 |
1 |
3 |
2 |
NM_078585.3 |
CG2028-RB, transcript variant B (CkIalpha), mRNA |
| 0 |
0 |
1 |
3 |
2 |
NM_167332.1 |
CG2028-RC, transcript variant C (CkIalpha), mRNA |
| 0 |
0 |
1 |
3 |
2 |
NM_167331.1 |
CG2028-RA, transcript variant A (CkIalpha), mRNA |
| 0 |
0 |
0 |
8 |
18 |
NM_164530.1 |
CG3347-RA (CG3347), mRNA |
| 0 |
0 |
0 |
4 |
5 |
NM_137773.1 |
CG13493-RA (comr), mRNA |
| 0 |
0 |
0 |
4 |
3 |
NM_001042854.1 |
CG12473-RB, transcript variant B (stnB), mRNA |
| 0 |
0 |
0 |
4 |
3 |
NM_001042853.1 |
CG12473-RA, transcript variant A (stnB), mRNA |
| 0 |
0 |
0 |
4 |
3 |
NM_001042852.1 |
CG12500-RB, transcript variant B (stnA), mRNA |
| 0 |
0 |
0 |
4 |
3 |
NM_001042851.1 |
CG12500-RA, transcript variant A (stnA), mRNA |
| 0 |
0 |
0 |
4 |
2 |
NM_137625.1 |
CG16868-RA (CG16868), mRNA |
| 0 |
0 |
0 |
3 |
4 |
NM_078542.4 |
CG15371-RA (Gr8a), mRNA |
| 0 |
0 |
0 |
3 |
4 |
NM_137537.2 |
CG15099-RA (CG15099), mRNA |
| 0 |
0 |
0 |
3 |
4 |
NM_140175.2 |
CG6297-RB, transcript variant B (JIL-1), mRNA |
| 0 |
0 |
0 |
3 |
4 |
NM_142135.1 |
CG14857-RA (CG14857), mRNA |
| 0 |
0 |
0 |
3 |
3 |
NM_168439.1 |
CG6297-RA, transcript variant A (JIL-1), mRNA |
| 0 |
0 |
0 |
3 |
2 |
NM_135536.2 |
CG4995-RA, transcript variant A (CG4995), mRNA |
| 0 |
0 |
0 |
3 |
2 |
NM_135559.2 |
CG5337-RA (CG5337), mRNA |
| 0 |
0 |
0 |
3 |
2 |
NM_164914.1 |
CG4995-RB, transcript variant B (CG4995), mRNA |
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Pathways (updated: 2024/04/26)
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| KEGG Pathway |
dme04080
:
Neuroactive ligand-receptor interaction
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