MG1655
W3110
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Gene Report : nanA
PEC Original Annotations
Essentiality
     Class non-essential
     References (PMID)  
Related gene (MG1655 PEC)
     Gene Search Search MG1655 PEC by gene name:  nanA
Related strains
     Strains Search Search strains by gene name:  nanA   Search strains by all related name:  nanA b3225 ECK3214 JW3194 npl

General information  (Go to Linear View:)
 Gene Name nanA  
 Alternative name b3225,ECK3214,JW3194,npl  
 Location, Length 3,372,538 - 3,373,431 (  -  ) ;   72.58 min ; 894 (bp) ,   297 (aa) Go to Linear View
 Product N-acetylneuraminate lyase  
 Note ECK3214:JW3194:b3225  
 Function  
 PID 85676018  
SWISS-PROT  ( Show details )
  botton Entry name(Acc.no) NANA_ECOLI ( P0A6L4 ; P06995; Q2M8Y8 )
    -  Protein name RecName: Full=N-acetylneuraminate lyase; EC=4.1.3.3; AltName: Full=N-acetylneuraminic acid aldolase; AltName: Full=N-acetylneuraminate pyruvate-lyase; AltName: Full=Sialic acid lyase; AltName: Full=Sialate lyase; AltName: Full=Sialic acid aldolase; AltName: Full=NALase;  
    -  Synonyms  
    -  Gene name Name=nanA; Synonyms=npl; OrderedLocusNames=b3225, JW3194;  

 Linear View
View Location
   3360.0  –  3385.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP  
    PDB
         PSI-BLAST  
    SWISS-PROT
         BLAST RecName: Full=N-acetylneuraminate lyase 1; AltName: Full=N-acetylneuraminic acid aldolase 1; AltName: Full=N-acetylneuraminate pyruvate-lyase 1; AltName: Full=Sialic acid lyase 1; AltName: Full=Sialate lyase 1; AltName: Full=Sialic acid aldolase 1  
        PSI-BLAST
    nr
         BLAST N-acetylneuraminate lyase [Escherichia coli O157:H7 EDL933]  
Pfam 27.0   (database updated : 2013-03 )
    Pfam

Other Cross-Reference
    EcoCyc nanA 

MMBR References
J Bacteriol. 1985;164(2):845-53.
Identification of an inducible catabolic system for sialic acids (nan) in Escherichia coli.
Vimr ER, Troy FA. ( 3902799 )

Sequences
Amino acid
FASTA format 
0001 MATNLRGVMA ALLTPFDQQQ ALDKASLRRL VQFNIQQGID GLYVGGSTGE AFVQSLSERE QVLEIVAEEA 
0071 KGKIKLIAHV GCVSTAESQQ LAASAKRYGF DAVSAVTPFY YPFSFEEHCD HYRAIIDSAD GLPMVVYNIP 
0141 ALSGVKLTLD QINTLVTLPG VGALKQTSGD LYQMEQIRRE HPDLVLYNGY DEIFASGLLA GADGGIGSTY 
0211 NIMGWRYQGI VKALKEGDIQ TAQKLQTECN KVIDLLIKTG VFRGLKTVLH YMDVVSVPLC RKPFGPVDEK 
0281 YLPELKALAQ QLMQERG
Nucleotide
FASTA format

View sequence out neighbor 100bp 
-100                                             cgcattataa gctttctgta tggggtgttg 
-070 cttaattgat ctggtataac aggtataaag gtatatcgtt tatcagacaa gcatcacttc agaggtattt 
0001 atggcaacga atttacgtgg cgtaatggct gcactcctga ctccttttga ccaacaacaa gcactggata 
0071 aagcgagtct gcgtcgcctg gttcagttca atattcagca gggcatcgac ggtttatacg tgggtggttc 
0141 gaccggcgag gcctttgtac aaagcctttc cgagcgtgaa caggtactgg aaatcgtcgc cgaagaggcg 
0211 aaaggtaaga ttaaactcat cgcccacgtc ggttgcgtca gcaccgccga aagccaacaa cttgcggcat 
0281 cggctaaacg ttatggcttc gatgccgtct ccgccgtcac gccgttctac tatcctttca gctttgaaga 
0351 acactgcgat cactatcggg caattattga ttcggcggat ggtttgccga tggtggtgta caacattcca 
0421 gccctgagtg gggtaaaact gaccctggat cagatcaaca cacttgttac attgcctggc gtaggtgcgc 
0491 tgaaacagac ctctggcgat ctctatcaga tggagcagat ccgtcgtgaa catcctgatc ttgtgctcta 
0561 taacggttac gacgaaatct tcgcctctgg tctgctggcg ggcgctgatg gtggtatcgg cagtacctac 
0631 aacatcatgg gctggcgcta tcaggggatc gttaaggcgc tgaaagaagg cgatatccag accgcgcaga 
0701 aactgcaaac tgaatgcaat aaagtcattg atttactgat caaaacgggc gtattccgcg gcctgaaaac 
0771 tgtcctccat tatatggatg tcgtttctgt gccgctgtgc cgcaaaccgt ttggaccggt agatgaaaaa 
0841 tatctgccag aactgaaggc gctggcccag cagttgatgc aagagcgcgg gtgagttgtt tcccctcgct 
0911 cgcccctacc gggtgagggg aaataaacgc atctgtaccc tacaattttc ataccaaagc gtgtgggcat 
0981 cgcccaccgc ggga