MG1655
W3110
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Gene Report : murC
PEC Original Annotations
Essentiality
     Class essential
     References (PMID)  
Related gene (MG1655 PEC)
     Gene Search Search MG1655 PEC by gene name:  murC
Related strains
     Strains Search Search strains by gene name:  murC   Search strains by all related name:  murC b0091 ECK0092 JW0089

General information  (Go to Linear View:)
 Gene Name murC  
 Alternative name b0091,ECK0092,JW0089  
 Location, Length 100,765 - 102,240 (  +  ) ;   2.17 min ; 1476 (bp) ,   491 (aa) Go to Linear View
 Product UDP-N-acetylmuramate:L-alanine ligase  
 Note ECK0092:JW0089:b0091  
 Function  
 PID 21321972  
SWISS-PROT  ( Show details )
  botton Entry name(Acc.no) MURC_ECOLI ( P17952 ; O07099 )
    -  Protein name RecName: Full=UDP-N-acetylmuramate--L-alanine ligase; EC=6.3.2.8; AltName: Full=UDP-N-acetylmuramoyl-L-alanine synthetase;  
    -  Synonyms  
    -  Gene name Name=murC; OrderedLocusNames=b0091, JW0089;  

 Linear View
View Location
   90.0  –  115.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP  
    PDB
        PSI-BLAST  
    SWISS-PROT
         BLAST RecName: Full=UDP-N-acetylmuramate--L-alanine ligase; AltName: Full=UDP-N-acetylmuramoyl-L-alanine synthetase  
         PSI-BLAST RecName: Full=UDP-N-acetylmuramate--L-alanine ligase; AltName: Full=UDP-N-acetylmuramoyl-L-alanine synthetase
    nr
         BLAST UDP-N-acetylmuramate:L-alanine ligase [Escherichia coli str. K-12 substr. MG1655]  
Pfam 27.0   (database updated : 2013-03 )
    Pfam

Other Cross-Reference
    EcoCyc murC 

MMBR References
J Bacteriol. 1980;143(3):1281-8.
Determination of transcriptional units and gene products from the ftsA region of Escherichia coli.
Lutkenhaus JF, Wu HC. ( 6447690 )

Sequences
Amino acid
FASTA format
0001 MNTQQLAKLR SIVPEMRRVR HIHFVGIGGA GMGGIAEVLA NEGYQISGSD LAPNPVTQQL MNLGATIYFN 
0071 HRPENVRDAS VVVVSSAISA DNPEIVAAHE ARIPVIRRAE MLAELMRFRH GIAIAGTHGK TTTTAMVSSI 
0141 YAEAGLDPTF VNGGLVKAAG VHARLGHGRY LIAEADESDA SFLHLQPMVA IVTNIEADHM DTYQGDFENL 
0211 KQTFINFLHN LPFYGRAVMC VDDPVIRELL PRVGRQTTTY GFSEDADVRV EDYQQIGPQG HFTLLRQDKE 
0281 PMRVTLNAPG RHNALNAAAA VAVATEEGID DEAILRALES FQGTGRRFDF LGEFPLEPVN GKSGTAMLVD 
0351 DYGHHPTEVD ATIKAARAGW PDKNLVMLFQ PHRFTRTRDL YDDFANVLTQ VDTLLMLEVY PAGEAPIPGA 
0421 DSRSLCRTIR GRGKIDPILV PDPARVAEML APVLTGNDLI LVQGAGNIGK IARSLAEIKL KPQTPEEEQH 
0491 D

Nucleotide
FASTA format

View sequence out neighbor 100bp
-100                                             CCACCGAGCG AGTGGCAAAT GAAGTGAGCC 
-070 GGGTTGCCCG GGCGTAATTG TAGCGATGCC TTTTGCATCG TATGAATTTA AGAAGTTAAT GGCGTAAAGA 
0001 atgaatacac aacaattggc aaaactgcgt tccatcgtgc ccgaaatgcg tcgcgttcgg cacatacatt 
0071 ttgtcggcat tggtggtgcc ggtatgggcg gtattgccga agttctggcc aatgaaggtt atcagatcag 
0141 tggttccgat ttagcgccaa atccggtcac gcagcagtta atgaatctgg gtgcgacgat ttatttcaac 
0211 catcgcccgg aaaacgtacg tgatgccagc gtggtcgttg tttccagcgc gatttctgcc gataacccgg 
0281 aaattgtcgc cgctcatgaa gcgcgtattc cggtgatccg tcgtgccgaa atgctggctg agttaatgcg 
0351 ttttcgtcat ggcatcgcca ttgccggaac gcacggcaaa acgacaacca ccgcgatggt ttccagcatc 
0421 tacgcagaag cggggctcga cccaaccttc gttaacggcg ggctggtaaa agcggcgggg gttcatgcgc 
0491 gtttggggca tggtcggtac ctgattgccg aagcagatga gagtgatgca tcgttcctgc atctgcaacc 
0561 gatggtggcg attgtcacca atatcgaagc cgaccacatg gatacctacc agggcgactt tgagaattta 
0631 aaacagactt ttattaattt tctgcacaac ctgccgtttt acggtcgtgc ggtgatgtgt gttgatgatc 
0701 cggtgatccg cgaattgtta ccgcgagtgg ggcgtcagac cacgacttac ggcttcagcg aagatgccga 
0771 cgtgcgtgta gaagattatc agcagattgg cccgcagggg cactttacgc tgctgcgcca ggacaaagag 
0841 ccgatgcgcg tcaccctgaa tgcgccaggt cgtcataacg cgctgaacgc cgcagctgcg gttgcggttg 
0911 ctacggaaga gggcattgac gacgaggcta ttttgcgggc gcttgaaagc ttccagggga ctggtcgccg 
0981 ttttgatttc ctcggtgaat tcccgctgga gccagtgaat ggtaaaagcg gtacggcaat gctggtcgat 
1051 gactacggcc accacccgac ggaagtggac gccaccatta aagcggcgcg cgcaggctgg ccggataaaa 
1121 acctggtaat gctgtttcag ccgcaccgtt ttacccgtac gcgcgacctg tatgatgatt tcgccaatgt 
1191 gctgacgcag gttgataccc tgttgatgct ggaagtgtat ccggctggcg aagcgccaat tccgggagcg 
1261 gacagccgtt cgctgtgtcg cacaattcgt ggacgtggga aaattgatcc cattctggtg ccggatccgg 
1331 cgcgggtagc cgagatgctg gcaccggtat taaccggtaa cgacctgatt ctcgttcagg gggctggtaa 
1401 tattggaaaa attgcccgtt ctttagctga aatcaaactg aagccgcaaa ctccggagga agaacaacat 
1471 gactgaTAAA ATCGCGGTCC TGTTGGGTGG GACCTCCGCT GAGCGGGAAG TTTCTCTGAA TTCTGGCGCA 
1541 GCGGTGTTAG CCGGACTGCG TGAAGGCGGT ATTGAC