MG1655
W3110
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Gene Report : murF
PEC Original Annotations
Essentiality
     Class essential
     References (PMID)  
Related gene (MG1655 PEC)
     Gene Search Search MG1655 PEC by gene name:  murF
Related strains
     Strains Search Search strains by gene name:  murF   Search strains by all related name:  murF b0086 ECK0087 JW0084 mra

General information  (Go to Linear View:)
 Gene Name murF  
 Alternative name b0086,ECK0087,JW0084,mra  
 Location, Length 94,650 - 96,008 (  +  ) ;   2.04 min ; 1359 (bp) ,   452 (aa) Go to Linear View
 Product UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D- alanine ligase  
 Note ECK0087:JW0084:b0086  
 Function  
 PID 85674322  
SWISS-PROT  ( Show details )
  botton Entry name(Acc.no) MURF_ECOLI ( P11880 ; O07100; P77636 )
    -  Protein name RecName: Full=UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; EC=6.3.2.10; AltName: Full=UDP-MurNAc-pentapeptide synthetase; AltName: Full=D-alanyl-D-alanine-adding enzyme;  
    -  Synonyms  
    -  Gene name Name=murF; Synonyms=mra; OrderedLocusNames=b0086, JW0084;  

 Linear View
View Location
   85.0  –  110.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP  
    PDB
        PSI-BLAST  
    SWISS-PROT
        BLAST  
        PSI-BLAST
    nr
         BLAST UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase [Escherichia coli str. K-12 substr. MG1655]  
Pfam 27.0   (database updated : 2013-03 )
    Pfam

Other Cross-Reference
    EcoCyc murF 

MMBR References
Nucleic Acids Res. 1989;17(13):5379
Nucleotide sequence of the murF gene encoding the UDP-MurNAc-pentapeptide synthetase of Escherichia coli.
Parquet C, Flouret B, Mengin-Lecreulx D, van Heijenoort J. ( 2668880 )

Sequences
Amino acid
FASTA format
0001 MISVTLSQLT DILNGELQGA DITLDAVTTD TRKLTPGCLF VALKGERFDA HDFADQAKAG GAGALLVSRP 
0071 LDIDLPQLIV KDTRLAFGEL AAWVRQQVPA RVVALTGSSG KTSVKEMTAA ILSQCGNTLY TAGNLNNDIG 
0141 VPMTLLRLTP EYDYAVIELG ANHQGEIAWT VSLTRPEAAL VNNLAAAHLE GFGSLAGVAK AKGEIFSGLP 
0211 ENGIAIMNAD NNDWLNWQSV IGSRKVWRFS PNAANSDFTA TNIHVTSHGT EFTLQTPTGS VDVLLPLPGR 
0281 HNIANALAAA ALSMSVGATL DAIKAGLANL KAVPGRLFPI QLAENQLLLD DSYNANVGSM TAAVQVLAEM 
0351 PGYRVLVVGD MAELGAESEA CHVQVGEAAK AAGIDRVLSV GKQSHAISTA SGVGEHFADK TALITRLKLL 
0421 IAEQQVITIL VKGSRSAAME EVVRALQENG TC

Nucleotide
FASTA format

View sequence out neighbor 100bp
-100                                             TGGTCGCGGG CAAAGGCCAT GAAGATTACC 
-070 AGATTGTTGG CAATCAGCGT CTGGACTACT CCGATCGCGT CACGGTGGCG CGTCTGCTGG GGGTGATTGC 
0001 atgattagcg taacccttag ccaacttacc gacattctca acggtgaact gcaaggtgca gatatcaccc 
0071 ttgatgctgt aaccactgat acccgaaaac tgacgccggg ctgcctgttt gttgccctga aaggcgaacg 
0141 ttttgatgcc cacgattttg ccgaccaggc gaaagctggc ggcgcaggcg cactactggt tagccgtccg 
0211 ctggacatcg acctgccgca gttaatcgtc aaggatacgc gtctggcgtt tggtgaactg gctgcatggg 
0281 ttcgccagca agttccggcg cgcgtggttg ctctgacggg gtcctccggc aaaacctccg ttaaagagat 
0351 gacggcggcg attttaagcc agtgcggcaa cacgctttat acggcaggca atctcaacaa cgacatcggt 
0421 gtaccgatga cgctgttgcg cttaacgccg gaatacgatt acgcagttat tgaacttggc gcgaaccatc 
0491 agggcgaaat agcctggact gtgagtctga ctcgcccgga agctgcgctg gtcaacaacc tggcagcggc 
0561 gcatctggaa ggttttggct cgcttgcggg tgtcgcgaaa gcgaaaggtg aaatctttag cggcctgccg 
0631 gaaaacggta tcgccattat gaacgccgac aacaacgact ggctgaactg gcagagcgta attggctcac 
0701 gcaaagtgtg gcgtttctca cccaatgccg ccaacagcga tttcaccgcc accaatatcc atgtgacctc 
0771 gcacggtacg gaatttaccc tacaaacccc aaccggtagc gtcgatgttc tgctgccgtt gccggggcgt 
0841 cacaatattg cgaatgcgct ggcagccgct gcgctctcca tgtccgtggg cgcaacgctt gatgctatca 
0911 aagcggggct ggcaaatctg aaagctgttc caggccgtct gttccccatc caactggcag aaaaccagtt 
0981 gctgctcgac gactcctaca acgccaatgt cggttcaatg actgcagcag tccaggtact ggctgaaatg 
1051 ccgggctacc gcgtgctggt ggtgggcgat atggcggaac tgggcgctga aagcgaagcc tgccatgtac 
1121 aggtgggcga ggcggcaaaa gctgctggta ttgaccgcgt gttaagcgtg ggtaaacaaa gccatgctat 
1191 cagcaccgcc agcggcgttg gcgaacattt tgctgataaa actgcgttaa ttacgcgtct taaattactg 
1261 attgctgagc aacaggtaat tacgatttta gttaagggtt cacgtagtgc cgccatggaa gaggtagtac 
1331 gcgctttaca ggagaatggg acatgttagT TTGGCTGGCC GAACATTTGG TCAAATATTA TTCCGGCTTT 
1401 AACGTCTTTT CCTATCTGAC GTTTCGCGCC ATCGTCAGCC TGCTGACCGC GCTGTTCAT