MG1655
W3110
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Gene Report : ftsI
PEC Original Annotations
Essentiality
     Class essential
     References (PMID)  
Related gene (MG1655 PEC)
     Gene Search Search MG1655 PEC by gene name:  ftsI
Related strains
     Strains Search Search strains by gene name:  ftsI   Search strains by all related name:  ftsI b0084 ECK0085 JW0082 pbpB sep

General information  (Go to Linear View:)
 Gene Name ftsI  
 Alternative name b0084,ECK0085,JW0082,pbpB,sep  
 Location, Length 91,413 - 93,179 (  +  ) ;   1.97 min ; 1767 (bp) ,   588 (aa) Go to Linear View
 Product transpeptidase involved in septal peptidoglycan synthesis  
 Note ECK0085:JW0082:b0084; penicillin-binding protein 3  
 Function  
 PID 21321965  
SWISS-PROT  ( Show details )
  botton Entry name(Acc.no) FTSI_ECOLI ( P0AD68 ; P04286 )
    -  Protein name RecName: Full=Peptidoglycan synthetase ftsI; EC=2.4.1.129; AltName: Full=Peptidoglycan glycosyltransferase 3; AltName: Full=Penicillin-binding protein 3; Short=PBP-3; Flags: Precursor;  
    -  Synonyms  
    -  Gene name Name=ftsI; Synonyms=pbpB; OrderedLocusNames=b0084, JW0082;  

 Linear View
View Location
   80.0  –  105.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP  
    PDB
        PSI-BLAST  
    SWISS-PROT
         BLAST RecName: Full=Peptidoglycan synthetase ftsI; AltName: Full=Peptidoglycan glycosyltransferase 3; AltName: Full=Penicillin-binding protein 3; Short=PBP-3; Flags: Precursor  
        PSI-BLAST
    nr
         BLAST septum formation; penicillin-binding protein 3; peptidoglycan synthetase [Escherichia coli O157:H7 EDL933]  
Pfam 27.0   (database updated : 2013-03 )
    Pfam

Other Cross-Reference
    EcoCyc ftsI 

MMBR References
Mol Gen Genet. 1983;191(1):1-9.
On the process of cellular division in Escherichia coli: nucleotide sequence of the gene for penicillin-binding protein 3.
Nakamura M, Maruyama IN, Soma M, Kato J, Suzuki H, Horota Y. ( 6350821 )

Sequences
Amino acid
FASTA format
0001 MKAAAKTQKP KRQEEHANFI SWRFALLCGC ILLALAFLLG RVAWLQVISP DMLVKEGDMR SLRVQQVSTS 
0071 RGMITDRSGR PLAVSVPVKA IWADPKEVHD AGGISVGDRW KALANALNIP LDQLSARINA NPKGRFIYLA 
0141 RQVNPDMADY IKKLKLPGIH LREESRRYYP SGEVTAHLIG FTNVDSQGIE GVEKSFDKWL TGQPGERIVR 
0211 KDRYGRVIED ISSTDSQAAH NLALSIDERL QALVYRELNN AVAFNKAESG SAVLVDVNTG EVLAMANSPS 
0281 YNPNNLSGTP KEAMRNRTIT DVFEPGSTVK PMVVMTALQR GVVRENSVLN TIPYRINGHE IKDVARYSEL 
0351 TLTGVLQKSS NVGVSKLALA MPSSALVDTY SRFGLGKATN LGLVGERSGL YPQKQRWSDI ERATFSFGYG 
0421 LMVTPLQLAR VYATIGSYGI YRPLSITKVD PPVPGERVFP ESIVRTVVHM MESVALPGGG GVKAAIKGYR 
0491 IAIKTGTAKK VGPDGRYINK YIAYTAGVAP ASQPRFALVV VINDPQAGKY YGGAVSAPVF GAIMGGVLRT 
0561 MNIEPDALTT GDKNEFVINQ GEGTGGRS

Nucleotide
FASTA format

View sequence out neighbor 100bp
-100                                             TAGCCGGGTG GAAAGGATCG CCACGGAAAA 
-070 GCTGCAAATG CAGCATGTTG ATCCGTCACA AGAAAATATC GTAGTGCAAA AATAAGGATA AACGCGACGC 
0001 atgaaagcag cggcgaaaac gcagaaacca aaacgtcagg aagaacatgc caactttatc agttggcgtt 
0071 ttgcgttgtt atgcggctgt attctcctgg cgctggcttt tctgctcgga cgcgtagcgt ggttacaagt 
0141 tatctccccg gatatgctgg tgaaagaggg cgacatgcgt tctcttcgcg ttcagcaagt ttccacctcc 
0211 cgcggcatga ttactgaccg ttctggtcgc ccgttagcgg tgagcgtgcc ggtaaaagcg atttgggctg 
0281 acccgaaaga agtgcatgac gctggcggta tcagcgtcgg tgaccgctgg aaggcgctgg ctaacgcgct 
0351 caatattccg ctggatcagc tttcagcccg cattaacgcc aacccgaaag ggcgctttat ttatctggcg 
0421 cgtcaggtga accctgacat ggcggactac atcaaaaaac tgaaactgcc ggggattcat ctgcgtgaag 
0491 agtctcgccg ttactatccg tccggcgaag tgactgctca cctcatcggc tttactaacg tcgatagtca 
0561 agggattgag ggcgttgaga agagtttcga taaatggctt accgggcagc cgggtgagcg cattgtgcgt 
0631 aaagaccgct atggtcgcgt aattgaagat atttcttcta ctgacagcca ggcagcgcac aacctggcgc 
0701 tgagtattga tgaacgcctg caggcgctgg tttatcgcga actgaacaac gcggtggcct ttaacaaggc 
0771 tgaatctggt agcgccgtgc tggtggatgt caacaccggt gaagtgctgg cgatggctaa cagcccgtca 
0841 tacaacccta acaatctgag cggcacgccg aaagaggcga tgcgtaaccg taccatcacc gacgtgtttg 
0911 aaccgggctc aacggttaaa ccgatggtgg taatgaccgc gttgcaacgt ggcgtggtgc gggaaaactc 
0981 ggtactcaat accattcctt atcgaattaa cggccacgaa atcaaagacg tggcacgcta cagcgaatta 
1051 accctgaccg gggtattaca gaagtcgagt aacgtcggtg tttccaagct ggcgttagcg atgccgtcct 
1121 cagcgttagt agatacttac tcacgttttg gactgggaaa agcgaccaat ttggggttgg tcggagaacg 
1191 cagtggctta tatcctcaaa aacaacggtg gtctgacata gagagggcca ccttctcttt cggctacggg 
1261 ctaatggtaa caccattaca gttagcgcga gtctacgcaa ctatcggcag ctacggcatt tatcgcccac 
1331 tgtcgattac caaagttgac cccccggttc ccggtgaacg tgtcttcccg gaatccattg tccgcactgt 
1401 ggtgcatatg atggaaagcg tggcgctacc aggcggcggc ggcgtgaagg cggcgattaa aggctatcgt 
1471 atcgccatta aaaccggtac cgcgaaaaag gtcgggccgg acggtcgcta catcaataaa tatattgctt 
1541 ataccgcagg cgttgcgcct gcgagtcagc cgcgcttcgc gctggttgtt gttatcaacg atccgcaggc 
1611 gggtaaatac tacggcggcg ccgtttccgc gccggtcttt ggtgccatca tgggcggcgt attgcgtacc 
1681 atgaacatcg agccggatgc gctgacaacg ggcgataaaa atgaatttgt gattaatcaa ggcgagggga 
1751 caggtggcag atcgtaaTTT GCGCGACCTT CTTGCTCCGT GGGTGCCAGA CGCACCTTCG CGAGCACTGC 
1821 GAGAGATGAC ACTCGACAGC CGTGTGGCTG CGGCGGGCGA TCTCTTT